Showing entry for Cationic amino acid transporter 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019016
Protein NameCationic amino acid transporter 3
Uniport IdQ8WY07
GeneSLC7A3
Gene Id84889
Domain_permease_2; _permease_C
Pfam PF13520   PF13906  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006865 amino acid transport
Biological Process GO:0097638 L-arginine import across plasma membrane
Biological Process GO:0097639 L-lysine import across plasma membrane
Biological Process GO:0097640 L-ornithine import across plasma membrane
Biological Process GO:1903352 L-ornithine transmembrane transport
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0015171 amino acid transmembrane transporter activity
molecular function GO:0015181 arginine transmembrane transporter activity
molecular function GO:0061459 L-arginine transmembrane transporter activity
molecular function GO:0015189 L-lysine transmembrane transporter activity
molecular function GO:0000064 L-ornithine transmembrane transporter activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-352230 Amino acid transport across the plasma membrane
R-HSA-382551 Transport of small molecules
R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
R-HSA-425407 SLC-mediated transmembrane transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0344529 BXGD007687 Cornea plana Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C2242776 BXGD017001 Plexiform leiomyoma
C3828416 BXGD019740 Radiation Damage Wounds and Injuries
C3840214 BXGD019795 High-functioning autism Mental Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000218 L-Lysine 146.19
BXGC0001630 Arginine 174.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein