Showing entry for CCR4-NOT transcription complex subunit 9


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019357
Protein NameCCR4-NOT transcription complex subunit 9
Uniport IdQ92600
GeneCNOT9
Gene Id9125
DomainRcd1
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa03018 RNA degradation
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Biological Process GO:0031047 gene silencing by RNA
Biological Process GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
Biological Process GO:0017148 negative regulation of translation
Biological Process GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
Biological Process GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
Biological Process GO:2000327 positive regulation of nuclear receptor transcription coactivator activity
Biological Process GO:0033138 positive regulation of peptidyl-serine phosphorylation
Biological Process GO:0007548 sex differentiation
molecular function GO:0005154 epidermal growth factor receptor binding
molecular function GO:0019900 kinase binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0030014 CCR4-NOT complex
cellular component GO:0030015 CCR4-NOT core complex
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0000932 P-body
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-212436 Generic Transcription Pathway
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-429914 Deadenylation-dependent mRNA decay
R-HSA-429947 Deadenylation of mRNA
R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis
R-HSA-5619507 Activation of HOX genes during differentiation
R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes
R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007112 BXGD000429 Adenocarcinoma of prostate Neoplasms; Male Urogenital Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0279680 BXGD006680 Transitional cell carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0001623 L-Tryptophan 204.23
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein