Showing entry for Adenocarcinoma of prostate


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000429
Disease NameAdenocarcinoma of prostate
Disease CUI IdC0007112
MeSH Codes C04   C12  
Disease Class NameNeoplasms; Male Urogenital Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O14980 BXGT004119 Exportin-1 7514 reviewed Receptor
O15169 BXGT004134 Axin-1 8312 reviewed
O15296 BXGT004148 Arachidonate 15-lipoxygenase B 247 reviewed Enzyme
O43255 BXGT004579 E3 ubiquitin-protein ligase SIAH2 6478 reviewed
O43521 BXGT004598 Bcl-2-like protein 11 10018 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43791 BXGT004626 Speckle-type POZ protein 8405 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60341 BXGT004873 Lysine-specific histone demethylase 1A 23028 reviewed Epigenetic regulator
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 11309 reviewed Transporter
O95644 BXGT005389 Nuclear factor of activated T-cells, cytoplasmic 1 4772 reviewed Transcription factor
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00739 BXGT005633 Haptoglobin-related protein 3250 reviewed Enzyme
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04083 BXGT006147 Annexin A1 301 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06241 BXGT006429 Tyrosine-protein kinase Fyn 2534 reviewed Kinase
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P07093 BXGT006544 Glia-derived nexin 5270 reviewed Enzyme modulator
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10909 BXGT007630 Clusterin 1191 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12273 BXGT007787 Prolactin-inducible protein 5304 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16471 BXGT008233 Prolactin receptor 5618 reviewed Signaling
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19793 BXGT008515 Retinoic acid receptor RXR-alpha 6256 reviewed Nuclear receptor
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21583 BXGT008667 Kit ligand 4254 reviewed
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27635 BXGT009194 60S ribosomal protein L10 6134 reviewed Nucleic acid binding
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30153 BXGT009409 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 5518 reviewed Enzyme
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31350 BXGT009526 Ribonucleoside-diphosphate reductase subunit M2 6241 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P39687 BXGT010131 Acidic leucine-rich nuclear phosphoprotein 32 family member A 8125 reviewed Enzyme modulator
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41143 BXGT010223 Delta-type opioid receptor 4985 reviewed G-protein coupled receptor
P42262 BXGT010294 Glutamate receptor 2 2891 reviewed Ion channel
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P52758 BXGT010951 2-iminobutanoate/2-iminopropanoate deaminase 10247 reviewed
P53041 BXGT010968 Serine/threonine-protein phosphatase 5 5536 reviewed
P54855 BXGT011088 UDP-glucuronosyltransferase 2B15 7366 reviewed
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P61006 BXGT011345 Ras-related protein Rab-8A 4218 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P68104 BXGT011575 Elongation factor 1-alpha 1 1915 reviewed Enzyme
P78330 BXGT011833 Phosphoserine phosphatase 5723 reviewed Enzyme
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q03154 BXGT012698 Aminoacylase-1 95 reviewed
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q04724 BXGT012778 Transducin-like enhancer protein 1 7088 reviewed Transcription factor
Q04759 BXGT012781 Protein kinase C theta type 5588 reviewed Kinase
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q08257 BXGT012975 Quinone oxidoreductase 1429 reviewed
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13418 BXGT013351 Integrin-linked protein kinase 3611 reviewed Kinase
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q14542 BXGT013482 Equilibrative nucleoside transporter 2 3177 reviewed Transporter
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 5163 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16513 BXGT013632 Serine/threonine-protein kinase N2 5586 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q7Z4W1 BXGT017257 L-xylulose reductase 51181 reviewed
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8NBS9 BXGT018543 Thioredoxin domain-containing protein 5 81567 reviewed
Q8TCS8 BXGT018799 Polyribonucleotide nucleotidyltransferase 1, mitochondrial 87178 reviewed Enzyme
Q8WWM9 BXGT019001 Cytoglobin 114757 reviewed
Q92600 BXGT019357 CCR4-NOT transcription complex subunit 9 9125 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q9BXT4 BXGT020175 Tudor domain-containing protein 1 56165 reviewed Enzyme
Q9H1D0 BXGT020445 Transient receptor potential cation channel subfamily V member 6 55503 reviewed Ion channel
Q9NRF2 BXGT021185 SH2B adapter protein 1 25970 reviewed
Q9NYA1 BXGT021254 Sphingosine kinase 1 8877 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
Q9Y5Y6 BXGT022308 Suppressor of tumorigenicity 14 protein 6768 reviewed Enzyme
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P63167 BXGT024120 Dynein light chain 1, cytoplasmic 8655 reviewed Cellular structure
Q9UKP6 BXGT024239 Urotensin-2 receptor 2837 reviewed G-protein coupled receptor
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease