protein

Showing entry for Nuclear receptor ROR-beta

General Target Information
BXGT Id	BXGT019369
Protein Name	Nuclear receptor ROR-beta
Uniport Id	Q92753
Gene	RORB
Gene Id
Domain	Hormone_recep; zf-C4
Pfam	PF00104 PF00105
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0035881	amacrine cell differentiation
Biological Process	GO:0071300	cellular response to retinoic acid
Biological Process	GO:0042462	eye photoreceptor cell development
Biological Process	GO:0045668	negative regulation of osteoblast differentiation
Biological Process	GO:0045892	negative regulation of transcription, DNA-templated
Biological Process	GO:0045893	positive regulation of transcription, DNA-templated
Biological Process	GO:0042752	regulation of circadian rhythm
Biological Process	GO:0006355	regulation of transcription, DNA-templated
Biological Process	GO:0060041	retina development in camera-type eye
Biological Process	GO:0046549	retinal cone cell development
Biological Process	GO:0046548	retinal rod cell development
Biological Process	GO:0048511	rhythmic process
Biological Process	GO:0006367	transcription initiation from RNA polymerase II promoter
Biological Process	GO:0007601	visual perception
molecular function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function	GO:0003700	DNA-binding transcription factor activity
molecular function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function	GO:0008502	melatonin receptor activity
molecular function	GO:0004879	nuclear receptor activity
molecular function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function	GO:1990837	sequence-specific double-stranded DNA binding
molecular function	GO:0008134	transcription factor binding
molecular function	GO:0008270	zinc ion binding
cellular component	GO:0000790	nuclear chromatin
cellular component	GO:0005654	nucleoplasm
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name
R-HSA-212436	Generic Transcription Pathway
R-HSA-383280	Nuclear Receptor transcription pathway
R-HSA-73857	RNA Polymerase II Transcription
R-HSA-74160	Gene expression (Transcription)

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002916	Melatonin		232.28
BXGC0005832	Acetophenone		120.15

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}