Showing entry for Melatonin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0002916
Compound NameMelatonin
Structure
FormulaC13H16N2O2
InchiKeyDRLFMBDRBRZALE-UHFFFAOYSA-N
SMILESCOC1=CC=C2NC=C(CCNC(C)=O)C2=C1
InchiInChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
IUPACN-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
Molecular Weight232.28
Pubchem Id896
Chembl IdCHEMBL45
Targets of Information Source
DrugBank DB01065
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A approved; nutraceutical; vet_approved agonist
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B approved; nutraceutical; vet_approved agonist
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 approved; nutraceutical; vet_approved antagonist
Q92753 BXGT019369 Nuclear receptor ROR-beta reviewed Nuclear receptor RORB approved; nutraceutical; vet_approved agonist
P0DP23 BXGT007520 Calmodulin-1 reviewed - CALM1 approved; nutraceutical; vet_approved -
P05164 BXGT006333 Myeloperoxidase reviewed Enzyme MPO approved; nutraceutical; vet_approved inhibitor
P11678 BXGT007736 Eosinophil peroxidase reviewed Enzyme EPX approved; nutraceutical; vet_approved inhibitor
P27797 BXGT009206 Calreticulin reviewed Calcium-binding protein CALR approved; nutraceutical; vet_approved -
P46597 BXGT010528 Acetylserotonin O-methyltransferase reviewed - ASMT approved; nutraceutical; vet_approved -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 approved; nutraceutical; vet_approved -
PDB ML1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - - - 1400 -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - - - - -
E9JSA3 BXGT003177 Phenolic oxidative coupling protein unreviewed hyp1 - - - - -
Q9LLQ2 BXGT021079 Class 10 plant pathogenesis-related protein 2B reviewed PR10.2B - - - - -
Q6P988 BXGT016462 Palmitoleoyl-protein carboxylesterase NOTUM reviewed NOTUM - - - - -
Binding DB 9019
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT008908 Acetylcholinesterase reviewed ACHE - >100 - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 11300 - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 1.48 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 1.11 - - -
reviewed BXGT009819 5-hydroxytryptamine receptor 5A reviewed Htr5a 1000 - - -
reviewed BXGT009820 5-hydroxytryptamine receptor 5B reviewed Htr5b 1000 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.23 - - -
reviewed BXGT010608 Melatonin receptor type 1A reviewed MTNR1A 0.24 - - -
reviewed BXGT009621 5-hydroxytryptamine receptor 7 reviewed Htr7 1000 - - -
reviewed BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A >10000 - - -
reviewed BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B >10000 - - -
reviewed BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C >10000 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.88 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.18 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.38 - - -
reviewed BXGT003958 Melatonin receptor type 1A (Fragment) reviewed MTNR1A 0.25 - - -
reviewed BXGT003958 Melatonin receptor type 1A (Fragment) reviewed MTNR1A 0.24 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.08 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.19 - - -
reviewed BXGT010829 Melatonin receptor type 1B (Fragment) reviewed - 1.21 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.56 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.66 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.48 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.33 - - -
reviewed BXGT010684 Melatonin receptor type 1C reviewed mtnr1c 1.87 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.29 - - -
reviewed BXGT010829 Melatonin receptor type 1B (Fragment) reviewed - 1.2 - - -
reviewed BXGT010684 Melatonin receptor type 1C reviewed mtnr1c 1.86 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.25 - - -
reviewed BXGT008059 5-hydroxytryptamine receptor 2A reviewed Htr2a >10000 - - -
reviewed BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B 5754.4 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.12 - - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 57 - - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 28 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.0823 - - -
reviewed BXGT010829 Melatonin receptor type 1B (Fragment) reviewed - 0.7 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.53 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.2 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.12 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.31 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B - - - 0.47
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - - - 1.92
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.195 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B - 0.3 - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - 0.6 - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - - - 2.24
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.14 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B - - - 0.49
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.41 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.3 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.4 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.53 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.32 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.41 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.0915 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.7 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.3 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.39 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.35 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.091 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - - - 0.098
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.15 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B - - - 0.069
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - 0.2 - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B - 0.53 - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.525 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.741 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.25 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.34 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.23 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.52 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - 1.1 - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.13 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.29 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.429 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.296 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B - - - 0.42
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - - - 1.5
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 65 - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.24 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.21 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.22 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - - - 0.026
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B - - - 0.82
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - - 9.2 -
reviewed BXGT010829 Melatonin receptor type 1B (Fragment) reviewed - 0.57 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - 0.017 - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - - - 2.2
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.37 - - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 6600 - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A - 1 - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 64.57 - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.617 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.331 - - -
reviewed BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A 0.263 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.339 - - -
reviewed BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B 0.5 - - -
CHEMBL CHEMBL45
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Imax - - -
P29475 BXGT009353 Nitric oxide synthase, brain reviewed - NOS1 Inhibition - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B EC50 '=' 0 nM
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Ki '=' 0 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 0 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Ki '=' 0 nM
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Activity '=' 19 pmol/min
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 10000 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 22387 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio Ki '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio Ki '=' 1 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 56234 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Relative affinity '=' 1 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Selectivity '=' 2 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Selectivity '=' 2 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 13 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 13 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Emax '=' 110 %
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A pRA1 '=' 0 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Emax '=' 100 %
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B EC50 '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IA '=' 1 -
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Ki '=' 0 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 0 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B EC50 '=' 0 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 12589 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 12589 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 6600 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A ECmax '=' 101 %
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P54132 BXGT011032 Bloom syndrome protein reviewed - BLM Potency '=' 1 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Ki '=' 0 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 0 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 0 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 133000 nM
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Ki '=' 0 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 0 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Relative potency '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Relative potency '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A EC50 '=' 1 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Kb '=' - -
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 28183 nM
Q9N1N9 BXGT021115 Carboxylic ester hydrolase unreviewed - BCHE IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Activity '=' 23 pmol/min
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 Ki '=' 56 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 1 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B pRA2 '=' 0 -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P49285 BXGT010690 Melatonin receptor type 1A reviewed - pRA '=' 0 -
P51050 BXGT010829 Melatonin receptor type 1B reviewed - pRA '=' 0 -
P49288 BXGT010692 Melatonin receptor type 1C reviewed - pRA '=' 0 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 2 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 2 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Intrinsic activity '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Activity - - -
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 71 %
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
P49219 BXGT010684 Melatonin receptor type 1C reviewed - mtnr1c EC50 '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Relative intrinsic activity '=' 1 -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 19952 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Emax '=' 104 %
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
O42275 BXGT004559 Acetylcholinesterase reviewed - ache IC50 - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Intrinsic activity '=' 1 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Kd '=' 9 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Kd '=' 9 -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 T1/2 '=' 0 hr
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 1 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 1 nM
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IAr '=' 1 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A EC50 '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B ECmax '=' 102 %
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A G-protein activation '=' 325 -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
P49219 BXGT010684 Melatonin receptor type 1C reviewed - mtnr1c EC50 '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Kb - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 '=' 10000 nM
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Activity '=' 100 %
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Activity '=' 100 %
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Activity '=' 100 %
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 39810 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Kd '=' 9 l M-1
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Kd '=' 9 l M-1
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Ki '=' 0 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 0 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IAr '=' 1 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Intrinsic activity '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio pKi '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio pKi '=' 1 -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 11300 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio '=' 0 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio '=' 0 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio '=' 0 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio '=' 0 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 3 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 3 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Index '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Index '=' 1 -
Q9R1U7 BXGT021423 Solute carrier family 22 member 8 reviewed - Slc22a8 Activity - - -
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 2119 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A EC50 '=' 2 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B EC50 '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B cAMP activity index '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A cAMP activity index '=' 1 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Activity - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Activity - - -
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Ki '=' 0 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 0 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio pKi '=' 0 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio pKi '=' 0 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Kb '=' - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 Imax '=' 75 %
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Emax '=' 100 %
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Inhibition '=' 100 %
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ka '=' 8 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ka '=' 8 -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Potency '=' 10000 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A EC50 '=' 0 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 794 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio '=' 1 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 15 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 15 nM
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 IC50 - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio '=' 0 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio '=' 0 -
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC Potency - 42163 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio '=' 0 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Ki '=' 0 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 0 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 2 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 2 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Relative affinity '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio '=' 3 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio '=' 3 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Imax - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 Ki '=' 27 nM
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Ki '=' 1 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 1 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Ki '=' 1 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A GTP-gammaS index '=' 1 -
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 37685 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A EC50 '=' 2 nM
Q9N1N9 BXGT021115 Carboxylic ester hydrolase unreviewed - BCHE IC50 '>' 100 nM
P49285 BXGT010690 Melatonin receptor type 1A reviewed - Relative affinity '=' 1 -
P51050 BXGT010829 Melatonin receptor type 1B reviewed - Relative affinity '=' 1 -
P49288 BXGT010692 Melatonin receptor type 1C reviewed - Relative affinity '=' 1 -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ratio '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ratio '=' 1 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A pRA '=' 0 -
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 39810 nM
Q9R1U7 BXGT021423 Solute carrier family 22 member 8 reviewed - Slc22a8 Activity '=' 30 %
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC Potency - 74978 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 0 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 64 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' 15 %
Q99549 BXGT019932 M-phase phosphoprotein 8 reviewed Epigenetic regulator MPHOSPH8 Potency - 177 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 64 nM
Q9Z0J4 BXGT022398 Nitric oxide synthase, brain reviewed - Nos1 Activity '=' 13 pmol/min
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P49285 BXGT010690 Melatonin receptor type 1A reviewed - EC50 '=' 22 nM
P51050 BXGT010829 Melatonin receptor type 1B reviewed - EC50 '=' 22 nM
P49288 BXGT010692 Melatonin receptor type 1C reviewed - EC50 '=' 22 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Inhibition '=' 100 %
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 14125 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 0 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 562 nM
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P06276 BXGT006430 Cholinesterase reviewed - BCHE IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B EC50 '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 0 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 Imax '=' 85 %
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 IC50 '=' 133000 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Kd '=' 0 nM
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
Q01453 BXGT012588 Peripheral myelin protein 22 reviewed Cellular structure PMP22 Potency '=' 84921 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 29081 nM
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A IC50 '=' 0 nM
P80244 BXGT011887 ATP-dependent Clp protease proteolytic subunit reviewed - clpP Potency - 28183 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki '=' 12000 nM
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B IC50 '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B pKi1-pKi2 '=' 0 -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A pKi1-pKi2 '=' 0 -
P81908 BXGT011959 Cholinesterase reviewed - BCHE IC50 - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition - - -
Q9Z0J4 BXGT022398 Nitric oxide synthase, brain reviewed - Nos1 Activity '=' 19 pmol/min
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Kb - - -
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 39810 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 28183 nM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 8492 nM
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 reviewed Transporter ABCC3 IC50 '=' 133000 nM
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B EC50 '=' 0 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' 1 %
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
P10145 BXGT007542 Interleukin-8 reviewed Signaling CXCL8 Potency - 74978 nM
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 22 %
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 '=' 5011 nM
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 2818 nM
P23795 BXGT008908 Acetylcholinesterase reviewed - ACHE IC50 '>' 100 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P27338 BXGT009172 Amine oxidase [flavin-containing] B reviewed - MAOB IC50 - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A EC50 '=' 1 nM
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Potency '=' 63 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 91 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 49 %
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A EC50 '=' 0 nM
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Ki '=' 0 nM
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A Kd '=' 0 nM
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
P97612 BXGT012211 Fatty-acid amide hydrolase 1 reviewed - Faah IC50 - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 24 %
O15439 BXGT004169 Multidrug resistance-associated protein 4 reviewed Transporter ABCC4 IC50 '=' 133000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 44 %
P04798 BXGT006265 Cytochrome P450 1A1 reviewed Enzyme CYP1A1 Ki '=' 59000 nM
Q16678 BXGT013656 Cytochrome P450 1B1 reviewed Enzyme CYP1B1 Ki '=' 14000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 19 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00006 Garden onion Allium cepa Vegetables
BXGF00022 Oat Avena sativa Cereals and cereal products
BXGF00088 Barley Hordeum vulgare Cereals and cereal products
BXGF00094 Common walnut Juglans regia Nuts
BXGF00105 Apple Malus pumila Fruits
BXGF00151 Pomegranate Punica granatum Fruits
BXGF00205 Corn Zea mays Cereals and cereal products
BXGF00206 Ginger Zingiber officinale Herbs and Spices
BXGF00289 Giant butterbur Petasites japonicus Vegetables
BXGF03671 Leonurus japonicus Leonurus japonicus Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease