Showing entry for Phosphorylase b kinase regulatory subunit beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019462
Protein NamePhosphorylase b kinase regulatory subunit beta
Uniport IdQ93100
GenePHKB
Gene Id5257
DomainGlyco_hydro_15
Pfam PF00723  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04922 Glucagon signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006091 generation of precursor metabolites and energy
Biological Process GO:0005980 glycogen catabolic process
Biological Process GO:0005977 glycogen metabolic process
Biological Process GO:0006468 protein phosphorylation
molecular function GO:0005516 calmodulin binding
molecular function GO:0003824 catalytic activity
cellular component GO:0005829 cytosol
cellular component GO:0005964 phosphorylase kinase complex
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1430728 Metabolism
R-HSA-70221 Glycogen breakdown (glycogenolysis)
R-HSA-70221 Glycogen breakdown (glycogenolysis)
R-HSA-71387 Metabolism of carbohydrates
R-HSA-71387 Metabolism of carbohydrates
R-HSA-8982491 Glycogen metabolism
R-HSA-8982491 Glycogen metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0017919 BXGD001150 Glycogen Storage Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0268147 BXGD005837 Glycogen storage disease, type IX Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0349588 BXGD007933 Short stature
C0543514 BXGD009282 Glycogen Storage Disease IXB Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1291390 BXGD012212 Deficiency of phosphorylase kinase
C1856285 BXGD015592 Increased hepatic glycogen content
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1968729 BXGD016730 Increased muscle glycogen content
C2919142 BXGD017867 Short Stature, CTCAE
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0024554 D-luciferin 280
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein