Showing entry for Sorting nexin-27


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019690
Protein NameSorting nexin-27
Uniport IdQ96L92
GeneSNX27
Gene Id81609
DomainPDZ_6; PX; RA
Pfam PF17820   PF00787   PF00788  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016197 endosomal transport
Biological Process GO:0008333 endosome to lysosome transport
Biological Process GO:0001770 establishment of natural killer cell polarity
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:1990126 retrograde transport, endosome to plasma membrane
Biological Process GO:0007165 signal transduction
molecular function GO:0032266 phosphatidylinositol-3-phosphate binding
molecular function GO:0035091 phosphatidylinositol binding
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0031901 early endosome membrane
cellular component GO:0005768 endosome
cellular component GO:0001772 immunological synapse
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020256 BXGD001370 Congenital Hydrocephalus Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0557874 BXGD009444 Global developmental delay
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1145670 BXGD011764 Respiratory Failure Respiratory Tract Diseases
C1855304 BXGD015484 MENTAL RETARDATION, AUTOSOMAL RECESSIVE 1 Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3489532 BXGD018934 Cone-Rod Dystrophy 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C3698357 BXGD019370 Refractory myoclonic epilepsy Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551549 BXGD023343 Early Infantile Epileptic Encephalopathy 6 Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006198 Citric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein