Showing entry for Oxysterol-binding protein-related protein 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020198
Protein NameOxysterol-binding protein-related protein 8
Uniport IdQ9BZF1
GeneOSBPL8
Gene Id114882
DomainOxysterol_BP; PH
Pfam PF01237   PF00169  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032148 activation of protein kinase B activity
Biological Process GO:0045444 fat cell differentiation
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0010891 negative regulation of sequestering of triglyceride
Biological Process GO:0036150 phosphatidylserine acyl-chain remodeling
Biological Process GO:0015914 phospholipid transport
Biological Process GO:0046326 positive regulation of glucose import
Biological Process GO:0046628 positive regulation of insulin receptor signaling pathway
Biological Process GO:0051897 positive regulation of protein kinase B signaling
Biological Process GO:0090204 protein localization to nuclear pore
molecular function GO:0015485 cholesterol binding
molecular function GO:0008289 lipid binding
molecular function GO:0070273 phosphatidylinositol-4-phosphate binding
molecular function GO:0001786 phosphatidylserine binding
molecular function GO:0140343 phosphatidylserine transfer activity
molecular function GO:0005548 phospholipid transporter activity
molecular function GO:0032934 sterol binding
molecular function GO:0015248 sterol transporter activity
cellular component GO:0032541 cortical endoplasmic reticulum
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0031965 nuclear membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1482801 Acyl chain remodelling of PS
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483257 Phospholipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0043094 BXGD003026 Weight Gain Pathological Conditions, Signs and Symptoms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C4525225 BXGD023128 Hamster Cholangiocarcinoma
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006368 Formic acid 46.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein