adisease

Showing entry for Weight Gain

General Disease Information
BXGD Id	BXGD003026
Disease Name	Weight Gain
Disease CUI Id	C0043094
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0001507
Human Phenotype Ontology Term	Growth abnormality
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00255	BXGT003903	Menin	4221	reviewed
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60427	BXGT004875	Acyl-CoA (8-3)-desaturase	3992	reviewed
O60895	BXGT004907	Receptor activity-modifying protein 2	10266	reviewed	Receptor
O94806	BXGT005335	Serine/threonine-protein kinase D3	23683	reviewed	Kinase
O95864	BXGT005403	Acyl-CoA 6-desaturase	9415	reviewed
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05156	BXGT006329	Complement factor I	3426	reviewed
P05230	BXGT006344	Fibroblast growth factor 1	2246	reviewed	Signaling
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P07355	BXGT006609	Annexin A2	302	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P08670	BXGT006810	Vimentin	7431	reviewed
P08758	BXGT006821	Annexin A5	308	reviewed
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10827	BXGT007623	Thyroid hormone receptor alpha	7067	reviewed	Nuclear receptor
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P17342	BXGT008302	Atrial natriuretic peptide receptor 3	4883	reviewed
P17612	BXGT008322	cAMP-dependent protein kinase catalytic subunit alpha	5566	reviewed	Kinase
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P24593	BXGT008979	Insulin-like growth factor-binding protein 5	3488	reviewed	Enzyme modulator
P27816	BXGT009209	Microtubule-associated protein 4	4134	reviewed
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P46940	BXGT010556	Ras GTPase-activating-like protein IQGAP1	8826	reviewed	Enzyme modulator
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P52895	BXGT010961	Aldo-keto reductase family 1 member C2	1646	reviewed	Enzyme
P54687	BXGT011067	Branched-chain-amino-acid aminotransferase, cytosolic	586	reviewed	Enzyme
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
P62241	BXGT011414	40S ribosomal protein S8	6202	reviewed	Nucleic acid binding
P62857	BXGT011466	40S ribosomal protein S28	6234	reviewed	Nucleic acid binding
P67936	BXGT011570	Tropomyosin alpha-4 chain	7171	reviewed	Cellular structure
Q01082	BXGT012567	Spectrin beta chain, non-erythrocytic 1	6711	reviewed
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	5530	reviewed
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q14449	BXGT013470	Growth factor receptor-bound protein 14	2888	reviewed	Receptor
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q8TDX7	BXGT018817	Serine/threonine-protein kinase Nek7	140609	reviewed	Kinase
Q9BZF1	BXGT020198	Oxysterol-binding protein-related protein 8	114882	reviewed
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9H0R4	BXGT020440	Haloacid dehalogenase-like hydrolase domain-containing protein 2	84064	reviewed	Enzyme
Q9HD40	BXGT020542	O-phosphoseryl-tRNA(Sec) selenium transferase	51091	reviewed
Q9HD67	BXGT020544	Unconventional myosin-X	4651	reviewed
Q9P246	BXGT021298	Stromal interaction molecule 2	57620	reviewed
Q9Y6M9	BXGT022336	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	4715	reviewed	Enzyme
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}