Showing entry for EH domain-containing protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020477
Protein NameEH domain-containing protein 1
Uniport IdQ9H4M9
GeneEHD1
Gene Id10938
DomainDUF5600; Dynamin_N; EF-hand_4; EHD_N
Pfam PF18150   PF00350   PF12763   PF16880  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007596 blood coagulation
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:0042632 cholesterol homeostasis
Biological Process GO:0060271 cilium assembly
Biological Process GO:0032456 endocytic recycling
Biological Process GO:0006897 endocytosis
Biological Process GO:0016197 endosomal transport
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0034383 low-density lipoprotein particle clearance
Biological Process GO:0031175 neuron projection development
Biological Process GO:0010886 positive regulation of cholesterol storage
Biological Process GO:2001137 positive regulation of endocytic recycling
Biological Process GO:1901741 positive regulation of myoblast fusion
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:0061512 protein localization to cilium
Biological Process GO:0072659 protein localization to plasma membrane
molecular function GO:0005524 ATP binding
molecular function GO:0045296 cadherin binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0005525 GTP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0017137 Rab GTPase binding
cellular component GO:0020018 ciliary pocket membrane
cellular component GO:0005769 early endosome
cellular component GO:0031901 early endosome membrane
cellular component GO:0030139 endocytic vesicle
cellular component GO:0010008 endosome membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005811 lipid droplet
cellular component GO:0016020 membrane
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0031095 platelet dense tubular network membrane
cellular component GO:0055038 recycling endosome membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-983231 Factors involved in megakaryocyte development and platelet production
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0024530 BXGD001783 Malaria Infections
C0025202 BXGD001832 melanoma Neoplasms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0085614 BXGD003205 First degree atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1536999 BXGD013348 cancer angiogenesis
C2936862 BXGD018148 Bardet-Biedl syndrome 1 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein