adisease

Showing entry for Cardiomyopathies

General Disease Information
BXGD Id	BXGD011368
Disease Name	Cardiomyopathies
Disease CUI Id	C0878544
MeSH Codes	C14
Disease Class Name	Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001626
Human Phenotype Ontology Term	Abnormality of the cardiovascular system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00142	BXGT003883	Thymidine kinase 2, mitochondrial	7084	reviewed	Kinase
O00187	BXGT003890	Mannan-binding lectin serine protease 2	10747	reviewed	Enzyme
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00408	BXGT003916	cGMP-dependent 3',5'-cyclic phosphodiesterase	5138	reviewed
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O14558	BXGT004070	Heat shock protein beta-6	126393	reviewed
O14672	BXGT004081	Disintegrin and metalloproteinase domain-containing protein 10	102	reviewed
O14786	BXGT004099	Neuropilin-1	8829	reviewed
O14832	BXGT004104	Phytanoyl-CoA dioxygenase, peroxisomal	5264	reviewed
O14907	BXGT004109	Tax1-binding protein 3	30851	reviewed
O14964	BXGT004116	Hepatocyte growth factor-regulated tyrosine kinase substrate	9146	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
O15440	BXGT004170	Multidrug resistance-associated protein 5	10057	reviewed	Transporter
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15488	BXGT004173	Glycogenin-2	8908	reviewed	Enzyme
O15553	BXGT004181	Pyrin	4210	reviewed
O43451	BXGT004594	Maltase-glucoamylase, intestinal	8972	reviewed	Enzyme
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O43766	BXGT004622	Lipoyl synthase, mitochondrial	11019	reviewed
O43772	BXGT004623	Mitochondrial carnitine/acylcarnitine carrier protein	788	reviewed	Transporter
O60271	BXGT004866	C-Jun-amino-terminal kinase-interacting protein 4	9043	reviewed	Enzyme modulator
O60563	BXGT004883	Cyclin-T1	904	reviewed	Enzyme modulator
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60706	BXGT004896	ATP-binding cassette sub-family C member 9	10060	reviewed	Transporter
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O60930	BXGT004910	Ribonuclease H1	246243	reviewed
O75112	BXGT005099	LIM domain-binding protein 3	11155	reviewed	Cellular structure
O75251	BXGT005107	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	374291	reviewed
O75306	BXGT005108	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	4720	reviewed	Enzyme
O75380	BXGT005120	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	4726	reviewed	Enzyme
O75390	BXGT005123	Citrate synthase, mitochondrial	1431	reviewed	Enzyme
O75828	BXGT005154	Carbonyl reductase [NADPH] 3	874	reviewed
O75880	BXGT005158	Protein SCO1 homolog, mitochondrial	6341	reviewed	Enzyme
O75923	BXGT005166	Dysferlin	8291	reviewed	Transporter
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
O76082	BXGT005175	Solute carrier family 22 member 5	6584	reviewed	Transporter
O94759	BXGT005327	Transient receptor potential cation channel subfamily M member 2	7226	reviewed	Ion channel
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O95235	BXGT005360	Kinesin-like protein KIF20A	10112	reviewed	Cellular structure
O95622	BXGT005386	Adenylate cyclase type 5	111	reviewed
O95718	BXGT005392	Steroid hormone receptor ERR2	2103	reviewed	Nuclear receptor
P00156	BXGT005469	Cytochrome b	4519	reviewed
P00338	BXGT005504	L-lactate dehydrogenase A chain	3939	reviewed	Enzyme
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00558	BXGT005579	Phosphoglycerate kinase 1	5230	reviewed	Kinase
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00846	BXGT005674	ATP synthase subunit a	4508	reviewed	Transporter
P00918	BXGT005690	Carbonic anhydrase 2	760	reviewed
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01031	BXGT005720	Complement C5	727	reviewed	Enzyme modulator
P01042	BXGT005722	Kininogen-1	3827	reviewed	Enzyme modulator
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02743	BXGT005937	Serum amyloid P-component	325	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04083	BXGT006147	Annexin A1	301	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05141	BXGT006325	ADP/ATP translocase 2	292	reviewed	Transporter
P05154	BXGT006327	Plasma serine protease inhibitor	5104	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05165	BXGT006334	Propionyl-CoA carboxylase alpha chain, mitochondrial	5095	reviewed	Enzyme
P05166	BXGT006335	Propionyl-CoA carboxylase beta chain, mitochondrial	5096	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05413	BXGT006355	Fatty acid-binding protein, heart	2170	reviewed
P05556	BXGT006368	Integrin beta-1	3688	reviewed	Receptor
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06576	BXGT006454	ATP synthase subunit beta, mitochondrial	506	reviewed	Transporter
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06703	BXGT006477	Protein S100-A6	6277	reviewed	Calcium-binding protein
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P06870	BXGT006518	Kallikrein-1	3816	reviewed	Enzyme
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P07438	BXGT006625	Metallothionein-1B	4490	reviewed
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08236	BXGT006752	Beta-glucuronidase	2990	reviewed
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P08588	BXGT006795	Beta-1 adrenergic receptor	153	reviewed	G-protein coupled receptor
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P09493	BXGT006900	Tropomyosin alpha-1 chain	7168	reviewed	Cellular structure
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P10253	BXGT007550	Lysosomal alpha-glucosidase	2548	reviewed	Enzyme
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11021	BXGT007644	Endoplasmic reticulum chaperone BiP	3309	reviewed
P11142	BXGT007658	Heat shock cognate 71 kDa protein	3312	reviewed
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	5292	reviewed	Kinase
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11474	BXGT007710	Steroid hormone receptor ERR1	2101	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P12081	BXGT007772	Histidine--tRNA ligase, cytoplasmic	3035	reviewed	Enzyme
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13866	BXGT007963	Sodium/glucose cotransporter 1	6523	reviewed	Transporter
P13945	BXGT007972	Beta-3 adrenergic receptor	155	reviewed	G-protein coupled receptor
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14410	BXGT008009	Sucrase-isomaltase, intestinal	6476	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14923	BXGT008069	Junction plakoglobin	3728	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15121	BXGT008083	Aldo-keto reductase family 1 member B1	231	reviewed	Enzyme
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15498	BXGT008133	Proto-oncogene vav	7409	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15848	BXGT008162	Arylsulfatase B	411	reviewed
P15924	BXGT008171	Desmoplakin	1832	reviewed	Cellular structure
P16066	BXGT008185	Atrial natriuretic peptide receptor 1	4881	reviewed	Kinase
P16109	BXGT008194	P-selectin	6403	reviewed
P16152	BXGT008201	Carbonyl reductase [NADPH] 1	873	reviewed
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P17050	BXGT008277	Alpha-N-acetylgalactosaminidase	4668	reviewed
P17174	BXGT008289	Aspartate aminotransferase, cytoplasmic	2805	reviewed
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18206	BXGT008389	Vinculin	7414	reviewed
P18564	BXGT008414	Integrin beta-6	3694	reviewed	Receptor
P18847	BXGT008431	Cyclic AMP-dependent transcription factor ATF-3	467	reviewed	Transcription factor
P19404	BXGT008477	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	4729	reviewed
P19429	BXGT008479	Troponin I, cardiac muscle	7137	reviewed	Cellular structure
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P19784	BXGT008513	Casein kinase II subunit alpha'	1459	reviewed	Kinase
P20132	BXGT008546	L-serine dehydratase/L-threonine deaminase	10993	reviewed	Enzyme
P20340	BXGT008566	Ras-related protein Rab-6A	5870	reviewed
P20702	BXGT008592	Integrin alpha-X	3687	reviewed
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21730	BXGT008687	C5a anaphylatoxin chemotactic receptor 1	728	reviewed	G-protein coupled receptor
P22033	BXGT008721	Methylmalonyl-CoA mutase, mitochondrial	4594	reviewed	Enzyme
P22083	BXGT008727	Alpha-(1,3)-fucosyltransferase 4	2526	reviewed	Enzyme
P22352	BXGT008758	Glutathione peroxidase 3	2878	reviewed	Enzyme
P22455	BXGT008772	Fibroblast growth factor receptor 4	2264	reviewed	Kinase
P22557	BXGT008783	5-aminolevulinate synthase, erythroid-specific, mitochondrial	212	reviewed	Enzyme
P22626	BXGT008787	Heterogeneous nuclear ribonucleoproteins A2/B1	3181	reviewed
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23526	BXGT008878	Adenosylhomocysteinase	191	reviewed	Enzyme
P23528	BXGT008879	Cofilin-1	1072	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P23946	BXGT008932	Chymase	1215	reviewed	Enzyme
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P24928	BXGT009001	DNA-directed RNA polymerase II subunit RPB1	5430	reviewed	Enzyme
P24941	BXGT009002	Cyclin-dependent kinase 2	1017	reviewed	Kinase
P25098	BXGT009015	Beta-adrenergic receptor kinase 1	156	reviewed	Kinase
P25100	BXGT009017	Alpha-1D adrenergic receptor	146	reviewed	G-protein coupled receptor
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P25103	BXGT009020	Substance-P receptor	6869	reviewed	G-protein coupled receptor
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28562	BXGT009270	Dual specificity protein phosphatase 1	1843	reviewed
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P29597	BXGT009367	Non-receptor tyrosine-protein kinase TYK2	7297	reviewed	Kinase
P30084	BXGT009398	Enoyl-CoA hydratase, mitochondrial	1892	reviewed	Enzyme
P30405	BXGT009423	Peptidyl-prolyl cis-trans isomerase F, mitochondrial	10105	reviewed
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P30559	BXGT009442	Oxytocin receptor	5021	reviewed	G-protein coupled receptor
P30626	BXGT009450	Sorcin	6717	reviewed
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	208	reviewed	Kinase
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P32418	BXGT009635	Sodium/calcium exchanger 1	6546	reviewed	Transporter
P33121	BXGT009692	Long-chain-fatty-acid--CoA ligase 1	2180	reviewed	Enzyme
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P33981	BXGT009744	Dual specificity protein kinase TTK	7272	reviewed	Kinase
P34947	BXGT009774	G protein-coupled receptor kinase 5	2869	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35573	BXGT009850	Glycogen debranching enzyme	178	reviewed	Enzyme
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36507	BXGT009923	Dual specificity mitogen-activated protein kinase kinase 2	5605	reviewed	Kinase
P36871	BXGT009936	Phosphoglucomutase-1	5236	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37288	BXGT009977	Vasopressin V1a receptor	552	reviewed	G-protein coupled receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42684	BXGT010331	Tyrosine-protein kinase ABL2	27	reviewed	Kinase
P42858	BXGT010341	Huntingtin	3064	reviewed
P43490	BXGT010395	Nicotinamide phosphoribosyltransferase	10135	reviewed	Signaling
P45379	BXGT010459	Troponin T, cardiac muscle	7139	reviewed	Cellular structure
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46939	BXGT010555	Utrophin	7402	reviewed
P46976	BXGT010558	Glycogenin-1	2992	reviewed	Enzyme
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	7498	reviewed	Enzyme
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49588	BXGT010713	Alanine--tRNA ligase, cytoplasmic	16	reviewed	Nucleic acid binding
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P49748	BXGT010733	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	37	reviewed	Enzyme
P49765	BXGT010738	Vascular endothelial growth factor B	7423	reviewed	Signaling
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P49840	BXGT010749	Glycogen synthase kinase-3 alpha	2931	reviewed	Kinase
P49888	BXGT010756	Estrogen sulfotransferase	6783	reviewed
P49959	BXGT010766	Double-strand break repair protein MRE11	4361	reviewed
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P50750	BXGT010818	Cyclin-dependent kinase 9	1025	reviewed	Kinase
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P51572	BXGT010859	B-cell receptor-associated protein 31	10134	reviewed	Transporter
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51688	BXGT010883	N-sulphoglucosamine sulphohydrolase	6448	reviewed	Enzyme
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P52564	BXGT010932	Dual specificity mitogen-activated protein kinase kinase 6	5608	reviewed	Kinase
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P54922	BXGT011093	[Protein ADP-ribosylarginine] hydrolase	141	reviewed	Enzyme
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P55157	BXGT011108	Microsomal triglyceride transfer protein large subunit	4547	reviewed	Transporter
P55789	BXGT011126	FAD-linked sulfhydryl oxidase ALR	2671	reviewed	Enzyme
P58004	BXGT011222	Sestrin-2	83667	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61160	BXGT011365	Actin-related protein 2	10097	reviewed	Cellular structure
P61587	BXGT011376	Rho-related GTP-binding protein RhoE	390	reviewed	Enzyme modulator
P61604	BXGT011380	10 kDa heat shock protein, mitochondrial	3336	reviewed	Chaperone
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P62736	BXGT011452	Actin, aortic smooth muscle	59	reviewed	Cellular structure
P62805	BXGT011457	Histone H4	8370	reviewed
P62820	BXGT011461	Ras-related protein Rab-1A	5861	reviewed
P62937	BXGT011471	Peptidyl-prolyl cis-trans isomerase A	5478	reviewed
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63316	BXGT011517	Troponin C, slow skeletal and cardiac muscles	7134	reviewed	Calcium-binding protein
P68106	BXGT011576	Peptidyl-prolyl cis-trans isomerase FKBP1B	2281	reviewed	Enzyme
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
P68363	BXGT011594	Tubulin alpha-1B chain	10376	reviewed	Cellular structure
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P78325	BXGT011832	Disintegrin and metalloproteinase domain-containing protein 8	101	reviewed	Enzyme
P78380	BXGT011841	Oxidized low-density lipoprotein receptor 1	4973	reviewed
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P81172	BXGT011935	Hepcidin	57817	reviewed
Q00059	BXGT012512	Transcription factor A, mitochondrial	7019	reviewed
Q00796	BXGT012549	Sorbitol dehydrogenase	6652	reviewed	Enzyme
Q02156	BXGT012639	Protein kinase C epsilon type	5581	reviewed	Kinase
Q02224	BXGT012643	Centromere-associated protein E	1062	reviewed	Cellular structure
Q02487	BXGT012656	Desmocollin-2	1824	reviewed	Cell adhesion
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q03933	BXGT012740	Heat shock factor protein 2	3298	reviewed	Transcription factor
Q04446	BXGT012764	1,4-alpha-glucan-branching enzyme	2632	reviewed	Enzyme
Q04917	BXGT012791	14-3-3 protein eta	7533	reviewed	Chaperone
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q07021	BXGT012915	Complement component 1 Q subcomponent-binding protein, mitochondrial	708	reviewed
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q07157	BXGT012920	Tight junction protein ZO-1	7082	reviewed	Cell-cell junction
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q07889	BXGT012946	Son of sevenless homolog 1	6654	reviewed	Enzyme modulator
Q07954	BXGT012950	Prolow-density lipoprotein receptor-related protein 1	4035	reviewed
Q09013	BXGT013023	Myotonin-protein kinase	1760	reviewed	Kinase
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	3757	reviewed	Ion channel
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13085	BXGT013309	Acetyl-CoA carboxylase 1	31	reviewed
Q13105	BXGT013311	Zinc finger and BTB domain-containing protein 17	7709	reviewed
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q13164	BXGT013322	Mitogen-activated protein kinase 7	5598	reviewed	Kinase
Q13418	BXGT013351	Integrin-linked protein kinase	3611	reviewed	Kinase
Q13423	BXGT013352	NAD(P) transhydrogenase, mitochondrial	23530	reviewed	Enzyme
Q13464	BXGT013357	Rho-associated protein kinase 1	6093	reviewed	Kinase
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q13976	BXGT013409	cGMP-dependent protein kinase 1	5592	reviewed	Kinase
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14126	BXGT013446	Desmoglein-2	1829	reviewed	Cell adhesion
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q14315	BXGT013460	Filamin-C	2318	reviewed
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q15020	BXGT013522	Squamous cell carcinoma antigen recognized by T-cells 3	9733	reviewed	Nucleic acid binding
Q15046	BXGT013527	Lysine--tRNA ligase	3735	reviewed	Enzyme
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15119	BXGT013541	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	5164	reviewed	Kinase
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q15208	BXGT013550	Serine/threonine-protein kinase 38	11329	reviewed	Kinase
Q15652	BXGT013587	Probable JmjC domain-containing histone demethylation protein 2C	221037	reviewed
Q15759	BXGT013595	Mitogen-activated protein kinase 11	5600	reviewed	Kinase
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16595	BXGT013643	Frataxin, mitochondrial	2395	reviewed	Enzyme
Q16654	BXGT013650	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	5166	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16718	BXGT013661	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	4698	reviewed	Enzyme
Q2M385	BXGT014131	Macrophage-expressed gene 1 protein	219972	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q32MK0	BXGT014323	Myosin light chain kinase 3	91807	reviewed	Kinase
Q59H18	BXGT015278	Serine/threonine-protein kinase TNNI3K	51086	reviewed
Q5JTZ9	BXGT015458	Alanine--tRNA ligase, mitochondrial	57505	reviewed	Nucleic acid binding
Q6ZVN8	BXGT016641	Hemojuvelin	148738	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q7Z406	BXGT017251	Myosin-14	79784	reviewed
Q8IVS2	BXGT018349	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial	27349	reviewed
Q8TD43	BXGT018806	Transient receptor potential cation channel subfamily M member 4	54795	reviewed	Ion channel
Q8WTS1	BXGT018985	1-acylglycerol-3-phosphate O-acyltransferase ABHD5	51099	reviewed
Q8WY64	BXGT019017	E3 ubiquitin-protein ligase MYLIP	29116	reviewed
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q92736	BXGT019367	Ryanodine receptor 2	6262	reviewed	Ion channel
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q92831	BXGT019380	Histone acetyltransferase KAT2B	8850	reviewed
Q92963	BXGT019401	GTP-binding protein Rit1	6016	reviewed	Enzyme modulator
Q969Q1	BXGT019610	E3 ubiquitin-protein ligase TRIM63	84676	reviewed
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96EN8	BXGT019649	Molybdenum cofactor sulfurase	55034	reviewed
Q96HC4	BXGT019671	PDZ and LIM domain protein 5	10611	reviewed	Cellular structure
Q96J02	BXGT019679	E3 ubiquitin-protein ligase Itchy homolog	83737	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96Q11	BXGT019713	CCA tRNA nucleotidyltransferase 1, mitochondrial	51095	reviewed
Q96RS0	BXGT019735	Trimethylguanosine synthase	96764	reviewed
Q96RT1	BXGT019736	Erbin	55914	reviewed
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	4217	reviewed	Kinase
Q99959	BXGT019977	Plakophilin-2	5318	reviewed	Cellular structure
Q9BPX6	BXGT020104	Calcium uptake protein 1, mitochondrial	10367	reviewed	Calcium-binding protein
Q9BXA7	BXGT020164	Testis-specific serine/threonine-protein kinase 1	83942	reviewed	Kinase
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9H1R3	BXGT020446	Myosin light chain kinase 2, skeletal/cardiac muscle	85366	reviewed	Kinase
Q9H251	BXGT020449	Cadherin-23	64072	reviewed
Q9H4M9	BXGT020477	EH domain-containing protein 1	10938	reviewed	Enzyme modulator
Q9H6Z9	BXGT020488	Egl nine homolog 3	112399	reviewed
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9HAS3	BXGT020507	Solute carrier family 28 member 3	64078	reviewed	Transporter
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NPD8	BXGT021152	Ubiquitin-conjugating enzyme E2 T	29089	reviewed
Q9NPI8	BXGT021161	Fanconi anemia group F protein	2188	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRH2	BXGT021188	SNF-related serine/threonine-protein kinase	54861	reviewed	Kinase
Q9NRM7	BXGT021190	Serine/threonine-protein kinase LATS2	26524	reviewed	Kinase
Q9NTG7	BXGT021211	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	23410	reviewed	Epigenetic regulator
Q9NWB1	BXGT021231	RNA binding protein fox-1 homolog 1	54715	reviewed	Nucleic acid binding
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9P0U3	BXGT021292	Sentrin-specific protease 1	29843	reviewed	Enzyme
Q9UBN7	BXGT021658	Histone deacetylase 6	10013	reviewed	Epigenetic regulator
Q9UGI6	BXGT021681	Small conductance calcium-activated potassium channel protein 3	3782	reviewed	Ion channel
Q9UGJ0	BXGT021683	5'-AMP-activated protein kinase subunit gamma-2	51422	reviewed	Enzyme modulator
Q9UIK4	BXGT021720	Death-associated protein kinase 2	23604	reviewed	Kinase
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9UQL6	BXGT021813	Histone deacetylase 5	10014	reviewed	Epigenetic regulator
Q9Y223	BXGT022207	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	10020	reviewed	Enzyme
Q9Y233	BXGT022210	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10846	reviewed
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y3D6	BXGT022257	Mitochondrial fission 1 protein	51024	reviewed
Q9Y3D8	BXGT022258	Adenylate kinase isoenzyme 6	102157402	reviewed
Q9Y478	BXGT022271	5'-AMP-activated protein kinase subunit beta-1	5564	reviewed	Kinase
Q9Y4E8	BXGT022276	Ubiquitin carboxyl-terminal hydrolase 15	9958	reviewed	Enzyme
Q9Y4K0	BXGT022280	Lysyl oxidase homolog 2	4017	reviewed
Q9Y572	BXGT022289	Receptor-interacting serine/threonine-protein kinase 3	11035	reviewed	Kinase
Q9Y5S1	BXGT022300	Transient receptor potential cation channel subfamily V member 2	51393	reviewed	Ion channel
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	10599	reviewed	Transporter
Q8WXS5	BXGT022657	Voltage-dependent calcium channel gamma-8 subunit	59283	reviewed	Ion channel
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P16615	BXGT023653	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	488	reviewed	Transporter
Q9NZM1	BXGT023948	Myoferlin	26509	reviewed	Transporter
O95399	BXGT024237	Urotensin-2	10911	reviewed
Q9UKP6	BXGT024239	Urotensin-2 receptor	2837	reviewed	G-protein coupled receptor
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
O43583	BXGT024866	Density-regulated protein	8562	reviewed	Enzyme
O14958	BXGT025138	Calsequestrin-2	845	reviewed
Q05086	BXGT025648	Ubiquitin-protein ligase E3A	7337	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
Q9Y2I7	BXGT026142	1-phosphatidylinositol 3-phosphate 5-kinase	200576	reviewed	Kinase
V9HWB9	BXGT026149	L-lactate dehydrogenase	3939	unreviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}