Showing entry for Neuromedin-U receptor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020514
Protein NameNeuromedin-U receptor 1
Uniport IdQ9HB89
GeneNMUR1
Gene Id10316
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007202 activation of phospholipase C activity
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0006821 chloride transport
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0048016 inositol phosphate-mediated signaling
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0006939 smooth muscle contraction
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0042924 neuromedin U binding
molecular function GO:0001607 neuromedin U receptor activity
molecular function GO:0008188 neuropeptide receptor activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0018889 BXGD001243 Helminthiasis Infections
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0030248 2-(4-Hydroxyphenyl)Chromen-4-One 238.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein