Showing entry for DNA-directed DNA/RNA polymerase mu


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021146
Protein NameDNA-directed DNA/RNA polymerase mu
Uniport IdQ9NP87
GenePOLM
Gene Id27434
DomainDNA_pol_B_palm; DNA_pol_B_thumb; DNA_pol_lambd_f; HHH_8
Pfam PF14792   PF14791   PF10391   PF14716  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.4 Replication and repair hsa03450 Non-homologous end-joining
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030183 B cell differentiation
Biological Process GO:0006310 DNA recombination
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0016446 somatic hypermutation of immunoglobulin genes
molecular function GO:0003677 DNA binding
molecular function GO:0003887 DNA-directed DNA polymerase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-5693532 DNA Double-Strand Break Repair
R-HSA-5693571 Nonhomologous End-Joining (NHEJ)
R-HSA-73894 DNA Repair
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005699 BXGD000325 Blast Phase Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0007097 BXGD000424 Carcinoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0345964 BXGD007755 Adenoma of lung Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0855146 BXGD011077 B Lymphoblastic Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1608408 BXGD013434 Malignant transformation
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002441 Hydroxyacetic acid 76.05
BXGC0002483 Oxalic acid 90.03
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0003705 Chloride 35.45
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein