Showing entry for Gamma-tubulin complex component 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021684
Protein NameGamma-tubulin complex component 4
Uniport IdQ9UGJ1
GeneTUBGCP4
Gene Id27229
DomainGCP_C_terminal; GCP_N_terminal
Pfam PF04130   PF17681  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031122 cytoplasmic microtubule organization
Biological Process GO:0051321 meiotic cell cycle
Biological Process GO:0007020 microtubule nucleation
Biological Process GO:0051415 microtubule nucleation by interphase microtubule organizing center
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0051225 spindle assembly
molecular function GO:0043015 gamma-tubulin binding
molecular function GO:0005200 structural constituent of cytoskeleton
cellular component GO:0005813 centrosome
cellular component GO:0005829 cytosol
cellular component GO:0000923 equatorial microtubule organizing center
cellular component GO:0000930 gamma-tubulin complex
cellular component GO:0008274 gamma-tubulin ring complex
cellular component GO:0016020 membrane
cellular component GO:0005874 microtubule
cellular component GO:0015630 microtubule cytoskeleton
cellular component GO:0055037 recycling endosome
cellular component GO:0000922 spindle pole
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
R-HSA-380287 Centrosome maturation
R-HSA-380320 Recruitment of NuMA to mitotic centrosomes
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-68877 Mitotic Prometaphase
R-HSA-68886 M Phase
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026010 BXGD001886 Microphthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0026826 BXGD001935 Muscle Hypertonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0202236 BXGD004086 Triglycerides measurement
C0234632 BXGD004691 Reduced visual acuity Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0339383 BXGD007245 Choroidal and/or chorioretinal disorder Eye Diseases
C0349588 BXGD007933 Short stature
C0392885 BXGD008071 High density lipoprotein measurement
C0523677 BXGD009215 Glycine measurement
C0557874 BXGD009444 Global developmental delay
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1840077 BXGD014434 Anteverted nostril
C1844505 BXGD014633 Pointed chin
C1849367 BXGD015046 Nasal bridge wide
C1854418 BXGD015402 Biparietal narrowing
C1855285 BXGD015483 Protruding ear
C1857679 BXGD015735 Sloping forehead
C1862475 BXGD016132 Abnormality of retinal pigmentation
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C1998028 BXGD016865 Photoreceptor degeneration Eye Diseases
C2675111 BXGD017272 Abnormal eyelash morphology
C2919142 BXGD017867 Short Stature, CTCAE
C3279222 BXGD018751 Aplasia/Hypoplasia of the cerebellum
C3502492 BXGD019046 Microcephaly with Chorioretinopathy, Autosomal Recessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4024809 BXGD021425 Chorioretinal dysplasia
C4225362 BXGD022240 MICROCEPHALY AND CHORIORETINOPATHY, AUTOSOMAL RECESSIVE, 3
C4551583 BXGD023361 Cerebral cortical atrophy
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein