Showing entry for Cerebral cortical atrophy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023361
Disease NameCerebral cortical atrophy
Disease CUI IdC4551583
MeSH Codes   
Disease Class Name
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00189 BXGT003891 AP-4 complex subunit mu-1 9179 reviewed Extracellular structure
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 10733 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14764 BXGT004094 Gamma-aminobutyric acid receptor subunit delta 2563 reviewed Ion channel
O14936 BXGT004114 Peripheral plasma membrane protein CASK 8573 reviewed Kinase
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O43914 BXGT004635 TYRO protein tyrosine kinase-binding protein 7305 reviewed
O75899 BXGT005161 Gamma-aminobutyric acid type B receptor subunit 2 9568 reviewed G-protein coupled receptor
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
O94903 BXGT005339 Pyridoxal phosphate homeostasis protein 11212 reviewed
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02679 BXGT005918 Fibrinogen gamma chain 2266 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P03905 BXGT006113 NADH-ubiquinone oxidoreductase chain 4 4538 reviewed Enzyme
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P03923 BXGT006115 NADH-ubiquinone oxidoreductase chain 6 4541 reviewed
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P06241 BXGT006429 Tyrosine-protein kinase Fyn 2534 reviewed Kinase
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15941 BXGT008176 Mucin-1 4582 reviewed
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P26640 BXGT009123 Valine--tRNA ligase 7407 reviewed
P30044 BXGT009395 Peroxiredoxin-5, mitochondrial 25824 reviewed
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 5605 reviewed Kinase
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P42858 BXGT010341 Huntingtin 3064 reviewed
P45381 BXGT010460 Aspartoacylase 443 reviewed
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P48058 BXGT010614 Glutamate receptor 4 2893 reviewed Ion channel
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase 501 reviewed Enzyme
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49810 BXGT010747 Presenilin-2 5664 reviewed Enzyme
P51572 BXGT010859 B-cell receptor-associated protein 31 10134 reviewed Transporter
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54886 BXGT011092 Delta-1-pyrroline-5-carboxylate synthase 5832 reviewed Enzyme
P58400 BXGT011235 Neurexin-1-beta 9378 reviewed
P60953 BXGT011342 Cell division control protein 42 homolog 998 reviewed Enzyme modulator
P61224 BXGT011370 Ras-related protein Rap-1b 5908 reviewed Enzyme modulator
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
Q00604 BXGT012538 Norrin 4693 reviewed
Q01831 BXGT012621 DNA repair protein complementing XP-C cells 7508 reviewed Nucleic acid binding
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q03468 BXGT012716 DNA excision repair protein ERCC-6 2074 reviewed
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q06830 BXGT012894 Peroxiredoxin-1 5052 reviewed Enzyme
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13303 BXGT013336 Voltage-gated potassium channel subunit beta-2 8514 reviewed Ion channel
Q13402 BXGT013348 Unconventional myosin-VIIa 4647 reviewed Cellular structure
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1859 reviewed Kinase
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q495M9 BXGT014765 Usher syndrome type-1G protein 124590 reviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q6PI48 BXGT016471 Aspartate--tRNA ligase, mitochondrial 55157 reviewed Enzyme
Q86SZ2 BXGT017602 Trafficking protein particle complex subunit 6B 122553 reviewed
Q96BZ9 BXGT019629 TBC1 domain family member 20 128637 reviewed
Q96C36 BXGT019631 Pyrroline-5-carboxylate reductase 2 29920 reviewed
Q96EQ8 BXGT019652 E3 ubiquitin-protein ligase RNF125 54941 reviewed
Q96GD0 BXGT019665 Pyridoxal phosphate phosphatase 57026 reviewed Enzyme
Q96QK1 BXGT019720 Vacuolar protein sorting-associated protein 35 55737 reviewed Transporter
Q96QU1 BXGT019721 Protocadherin-15 65217 reviewed
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 3028 reviewed Enzyme
Q99798 BXGT019962 Aconitate hydratase, mitochondrial 50 reviewed Enzyme
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9H251 BXGT020449 Cadherin-23 64072 reviewed
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase 57704 reviewed
Q9NP72 BXGT021144 Ras-related protein Rab-18 22931 reviewed
Q9NSE4 BXGT021207 Isoleucine--tRNA ligase, mitochondrial 55699 reviewed Enzyme
Q9UBK8 BXGT021655 Methionine synthase reductase 4552 reviewed
Q9UGJ1 BXGT021684 Gamma-tubulin complex component 4 27229 reviewed Cellular structure
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9Y263 BXGT022220 Phospholipase A-2-activating protein 9373 reviewed Enzyme modulator
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y2I2 BXGT022236 Netrin-G1 22854 reviewed Enzyme modulator
Q9Y4U1 BXGT022285 Methylmalonic aciduria and homocystinuria type C protein 25974 reviewed
Q9Y619 BXGT022316 Mitochondrial ornithine transporter 1 10166 reviewed Transporter
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
Q9Y6N9 BXGT022337 Harmonin 10083 reviewed Cellular structure
Q15878 BXGT022659 Voltage-dependent R-type calcium channel subunit alpha-1E 777 reviewed Ion channel
Q9Y5W7 BXGT022783 Sorting nexin-14 57231 reviewed Enzyme modulator
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
Q59FF6 BXGT023693 Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant 2074 unreviewed
Q9H9S5 BXGT024623 Fukutin-related protein 79147 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
P28715 BXGT025675 DNA repair protein complementing XP-G cells 2073 reviewed
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease