Showing entry for Nocturnin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021737
Protein NameNocturnin
Uniport IdQ9UK39
GeneNOCT
Gene Id25819
DomainExo_endo_phos
Pfam PF03372  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032922 circadian regulation of gene expression
Biological Process GO:0007623 circadian rhythm
Biological Process GO:0033962 cytoplasmic mRNA processing body assembly
Biological Process GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
Biological Process GO:0048255 mRNA stabilization
Biological Process GO:0006739 NADP metabolic process
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0045668 negative regulation of osteoblast differentiation
Biological Process GO:0045600 positive regulation of fat cell differentiation
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0045995 regulation of embryonic development
Biological Process GO:0009991 response to extracellular stimulus
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0006366 transcription by RNA polymerase II
molecular function GO:0000175 3'-5'-exoribonuclease activity
molecular function GO:0046872 metal ion binding
molecular function GO:0003729 mRNA binding
molecular function GO:0102757 NADPH phosphatase activity
molecular function GO:0019178 NADP phosphatase activity
molecular function GO:0004535 poly(A)-specific ribonuclease activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005739 mitochondrion
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0000932 P-body
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression
R-HSA-400253 Circadian Clock
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0020981 BXGD001474 Angioimmunoblastic Lymphadenopathy Immune System Diseases; Hemic and Lymphatic Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024307 BXGD001765 Lymphomatoid Granulomatosis Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0206141 BXGD004160 Idiopathic Hypereosinophilic Syndrome Hemic and Lymphatic Diseases
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306759 BXGD012374 Eosinophilic disorder Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein