Showing entry for ADP-sugar pyrophosphatase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021745
Protein NameADP-sugar pyrophosphatase
Uniport IdQ9UKK9
GeneNUDT5
Gene Id11164
DomainNUDIX
Pfam PF00293  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990966 ATP generation from poly-ADP-D-ribose
Biological Process GO:0006338 chromatin remodeling
Biological Process GO:0019303 D-ribose catabolic process
Biological Process GO:0034656 nucleobase-containing small molecule catabolic process
Biological Process GO:0006753 nucleoside phosphate metabolic process
Biological Process GO:0009117 nucleotide metabolic process
Biological Process GO:0009191 ribonucleoside diphosphate catabolic process
Biological Process GO:0019693 ribose phosphate metabolic process
molecular function GO:0044715 8-oxo-dGDP phosphatase activity
molecular function GO:0047631 ADP-ribose diphosphatase activity
molecular function GO:0019144 ADP-sugar diphosphatase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0016779 nucleotidyltransferase activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0030515 snoRNA binding
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-2393930 Phosphate bond hydrolysis by NUDT proteins
R-HSA-74259 Purine catabolism
R-HSA-8956319 Nucleobase catabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2945759 BXGD018189 aggressive cancer
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0024261 Adenosine Phosphate 347.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein