adisease

Showing entry for aggressive cancer

General Disease Information
BXGD Id	BXGD018189
Disease Name	aggressive cancer
Disease CUI Id	C2945759
MeSH Codes
Disease Class Name
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00560	BXGT003937	Syntenin-1	6386	reviewed	Transporter
O43175	BXGT004575	D-3-phosphoglycerate dehydrogenase	26227	reviewed	Enzyme
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08151	BXGT006731	Zinc finger protein GLI1	2735	reviewed
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P11926	BXGT007760	Ornithine decarboxylase	4953	reviewed	Enzyme
P14618	BXGT008027	Pyruvate kinase PKM	5315	reviewed	Kinase
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15311	BXGT008106	Ezrin	7430	reviewed	Cellular structure
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P29317	BXGT009331	Ephrin type-A receptor 2	1969	reviewed	Kinase
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	7433	reviewed	G-protein coupled receptor
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P55786	BXGT011125	Puromycin-sensitive aminopeptidase	9520	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	5745	reviewed	G-protein coupled receptor
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q13043	BXGT013307	Serine/threonine-protein kinase 4	6789	reviewed	Kinase
Q13464	BXGT013357	Rho-associated protein kinase 1	6093	reviewed	Kinase
Q13526	BXGT013369	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5300	reviewed
Q13887	BXGT013401	Krueppel-like factor 5	688	reviewed	Nucleic acid binding
Q6PL18	BXGT016479	ATPase family AAA domain-containing protein 2	29028	reviewed	Epigenetic regulator
Q96LA8	BXGT019691	Protein arginine N-methyltransferase 6	55170	reviewed	Epigenetic regulator
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q9NYA1	BXGT021254	Sphingosine kinase 1	8877	reviewed	Kinase
Q9NZI8	BXGT021273	Insulin-like growth factor 2 mRNA-binding protein 1	10642	reviewed	Enzyme
Q9UKK9	BXGT021745	ADP-sugar pyrophosphatase	11164	reviewed	Enzyme
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
P35240	BXGT022927	Merlin	4771	reviewed
Q8NEU8	BXGT022976	DCC-interacting protein 13-beta	55198	reviewed
Q99748	BXGT023217	Neurturin	4902	reviewed	Signaling

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}