Showing entry for C-type lectin domain family 4 member A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021777
Protein NameC-type lectin domain family 4 member A
Uniport IdQ9UMR7
GeneCLEC4A
Gene Id50856
DomainLectin_C
Pfam PF00059  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
Biological Process GO:0036037 CD8-positive, alpha-beta T cell activation
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0045087 innate immune response
Biological Process GO:0001818 negative regulation of cytokine production
Biological Process GO:0032720 negative regulation of tumor necrosis factor production
Biological Process GO:0002470 plasmacytoid dendritic cell antigen processing and presentation
Biological Process GO:0002223 stimulatory C-type lectin receptor signaling pathway
Biological Process GO:0016032 viral process
molecular function GO:0005509 calcium ion binding
molecular function GO:0030246 carbohydrate binding
molecular function GO:0005537 mannose binding
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-5621480 Dectin-2 family
R-HSA-5621481 C-type lectin receptors (CLRs)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0008373 BXGD000536 Cholesteatoma Skin and Connective Tissue Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0020517 BXGD001415 Hypersensitivity Immune System Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0151449 BXGD003419 Primary Sjögren's syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0275518 BXGD006375 Acute infectious disease Pathological Conditions, Signs and Symptoms; Infections
C1527304 BXGD013266 Allergic Reaction Immune System Diseases
C2363741 BXGD017100 HIV-1 infection
C4280669 BXGD022382 Velopharyngeal dysfunction
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein