adisease

Showing entry for Allergic Reaction

General Disease Information
BXGD Id	BXGD013266
Disease Name	Allergic Reaction
Disease CUI Id	C1527304
MeSH Codes	C20
Disease Class Name	Immune System Diseases
Semantic Type	Pathologic Function
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00462	BXGT003925	Beta-mannosidase	4126	reviewed	Enzyme
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75362	BXGT005114	Zinc finger protein 217	7764	reviewed
O95256	BXGT005364	Interleukin-18 receptor accessory protein	8807	reviewed	Receptor
P01042	BXGT005722	Kininogen-1	3827	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01903	BXGT005814	HLA class II histocompatibility antigen, DR alpha chain	3122	reviewed	Immune response
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02775	BXGT005960	Platelet basic protein	5473	reviewed	Signaling
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P16109	BXGT008194	P-selectin	6403	reviewed
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P21580	BXGT008666	Tumor necrosis factor alpha-induced protein 3	7128	reviewed	Enzyme
P21860	BXGT008698	Receptor tyrosine-protein kinase erbB-3	2065	reviewed	Kinase
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P26012	BXGT009083	Integrin beta-8	3696	reviewed	Receptor
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42226	BXGT010288	Signal transducer and activator of transcription 6	6778	reviewed	Nucleic acid binding
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P46940	BXGT010556	Ras GTPase-activating-like protein IQGAP1	8826	reviewed	Enzyme modulator
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P51686	BXGT010881	C-C chemokine receptor type 9	10803	reviewed	G-protein coupled receptor
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P52564	BXGT010932	Dual specificity mitogen-activated protein kinase kinase 6	5608	reviewed	Kinase
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60900	BXGT011338	Proteasome subunit alpha type-6	5687	reviewed
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
P80075	BXGT011876	C-C motif chemokine 8	6355	reviewed	Signaling
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q01344	BXGT012585	Interleukin-5 receptor subunit alpha	3568	reviewed	Signaling
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13838	BXGT013397	Spliceosome RNA helicase DDX39B	7919	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14392	BXGT013465	Transforming growth factor beta activator LRRC32	2615	reviewed	Receptor
Q14573	BXGT013486	Inositol 1,4,5-trisphosphate receptor type 3	3710	reviewed	Ion channel
Q15080	BXGT013535	Neutrophil cytosol factor 4	4689	reviewed
Q15262	BXGT013555	Receptor-type tyrosine-protein phosphatase kappa	5796	reviewed	Enzyme
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q16348	BXGT013627	Solute carrier family 15 member 2	6565	reviewed	Transporter
Q16773	BXGT013667	Kynurenine--oxoglutarate transaminase 1	883	reviewed	Enzyme
Q30154	BXGT014296	HLA class II histocompatibility antigen, DR beta 5 chain	3127	reviewed	Immune response
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8TAX9	BXGT018788	Gasdermin-B	55876	reviewed
Q8WUI4	BXGT018992	Histone deacetylase 7	51564	reviewed	Epigenetic regulator
Q92835	BXGT019382	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1	3635	reviewed
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UMR7	BXGT021777	C-type lectin domain family 4 member A	50856	reviewed	Receptor
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9Y4B6	BXGT022272	DDB1- and CUL4-associated factor 1	9730	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}