Showing entry for Phenylalanine--tRNA ligase alpha subunit


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022224
Protein NamePhenylalanine--tRNA ligase alpha subunit
Uniport IdQ9Y285
GeneFARSA
Gene Id2193
DomainPheRS_DBD1; PheRS_DBD2; PheRS_DBD3; tRNA-synt_2d
Pfam PF18552   PF18554   PF18553   PF01409  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa00970 Aminoacyl-tRNA biosynthesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006432 phenylalanyl-tRNA aminoacylation
Biological Process GO:0051290 protein heterotetramerization
Biological Process GO:0006418 tRNA aminoacylation for protein translation
molecular function GO:0005524 ATP binding
molecular function GO:0004826 phenylalanine-tRNA ligase activity
molecular function GO:0003723 RNA binding
molecular function GO:0000049 tRNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0009328 phenylalanine-tRNA ligase complex
Reactome
Pathway Id Pathway Name
R-HSA-379716 Cytosolic tRNA aminoacylation
R-HSA-379724 tRNA Aminoacylation
R-HSA-392499 Metabolism of proteins
R-HSA-72766 Translation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0014772 BXGD000948 Red Blood Cell Count measurement
C0017654 BXGD001136 Glomerular Filtration Rate
C0020445 BXGD001386 Hypercholesterolemia, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0343401 BXGD007623 MRSA - Methicillin resistant Staphylococcus aureus infection Infections
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003214 L-(-)-Phenylalanine 165.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein