Showing entry for FACT complex subunit SPT16



                       
General Target Information
BXGT IdBXGT022291
Protein NameFACT complex subunit SPT16
Uniport IdQ9Y5B9
GeneSUPT16H
Gene Id11198
DomainFACT-Spt16_Nlob; Peptidase_M24; Rtt106; SPT16
Pfam PF14826   PF00557   PF08512   PF08644  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006281 DNA repair
Biological Process GO:0006260 DNA replication
Biological Process GO:0034724 DNA replication-independent nucleosome organization
Biological Process GO:0006337 nucleosome disassembly
Biological Process GO:0032786 positive regulation of DNA-templated transcription, elongation
Biological Process GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
Biological Process GO:1901796 regulation of signal transduction by p53 class mediator
Biological Process GO:0006366 transcription by RNA polymerase II
Biological Process GO:0006368 transcription elongation from RNA polymerase II promoter
Biological Process GO:0016032 viral process
molecular function GO:0042393 histone binding
molecular function GO:0031491 nucleosome binding
molecular function GO:0003723 RNA binding
cellular component GO:0035101 FACT complex
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-112382 Formation of RNA Pol II elongation complex
R-HSA-162587 HIV Life Cycle
R-HSA-162599 Late Phase of HIV Life Cycle
R-HSA-162906 HIV Infection
R-HSA-1643685 Disease
R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat
R-HSA-167169 HIV Transcription Elongation
R-HSA-167172 Transcription of the HIV genome
R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat
R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation
R-HSA-167243 Tat-mediated HIV elongation arrest and recovery
R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript
R-HSA-167287 HIV elongation arrest and recovery
R-HSA-167290 Pausing and recovery of HIV elongation
R-HSA-212436 Generic Transcription Pathway
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-5663205 Infectious disease
R-HSA-674695 RNA Polymerase II Pre-transcription Events
R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-75955 RNA Polymerase II Transcription Elongation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0004936 BXGD000295 Mental disorders Mental Disorders
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0557874 BXGD009444 Global developmental delay
C0596887 BXGD009648 mathematical ability
C1367536 BXGD012884 Nasopharyngeal Angiofibroma Neoplasms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1842581 BXGD014525 Abnormal corpus callosum morphology Pathological Conditions, Signs and Symptoms
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0006368 Formic acid 46.03
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein