adisease

Showing entry for Abnormal behavior

General Disease Information
BXGD Id	BXGD004584
Disease Name	Abnormal behavior
Disease CUI Id	C0233514
MeSH Codes	F01
Disease Class Name	Behavior and Behavior Mechanisms
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A1Z1Q3	BXGT001069	ADP-ribose glycohydrolase MACROD2	140733	reviewed
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00303	BXGT003906	Eukaryotic translation initiation factor 3 subunit F	8665	reviewed	Enzyme
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00418	BXGT003918	Eukaryotic elongation factor 2 kinase	29904	reviewed	Kinase
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
O00571	BXGT003938	ATP-dependent RNA helicase DDX3X	1654	reviewed
O00755	BXGT003945	Protein Wnt-7a	7476	reviewed	Signaling
O14818	BXGT004103	Proteasome subunit alpha type-7	5688	reviewed
O15075	BXGT004124	Serine/threonine-protein kinase DCLK1	9201	reviewed	Kinase
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O15409	BXGT004166	Forkhead box protein P2	93986	reviewed
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15550	BXGT004179	Lysine-specific demethylase 6A	7403	reviewed	Epigenetic regulator
O43181	BXGT004576	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	4724	reviewed
O43272	BXGT004580	Proline dehydrogenase 1, mitochondrial	5625	reviewed	Enzyme
O43521	BXGT004598	Bcl-2-like protein 11	10018	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O43914	BXGT004635	TYRO protein tyrosine kinase-binding protein	7305	reviewed
O43915	BXGT004636	Vascular endothelial growth factor D	2277	reviewed	Signaling
O60242	BXGT004861	Adhesion G protein-coupled receptor B3	577	reviewed	G-protein coupled receptor
O60259	BXGT004863	Kallikrein-8	11202	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75129	BXGT005101	Astrotactin-2	23245	reviewed
O75164	BXGT005104	Lysine-specific demethylase 4A	9682	reviewed
O75581	BXGT005136	Low-density lipoprotein receptor-related protein 6	4040	reviewed
O75628	BXGT005140	GTP-binding protein REM 1	28954	reviewed
O75751	BXGT005150	Solute carrier family 22 member 3	6581	reviewed	Transporter
O76039	BXGT005171	Cyclin-dependent kinase-like 5	6792	reviewed	Kinase
O94811	BXGT005336	Tubulin polymerization-promoting protein	11076	reviewed	Cellular structure
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	2744	reviewed	Enzyme
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
O95264	BXGT005367	5-hydroxytryptamine receptor 3B	9177	reviewed	Ion channel
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
O95696	BXGT005390	Bromodomain-containing protein 1	23774	reviewed
O95970	BXGT005409	Leucine-rich glioma-inactivated protein 1	9211	reviewed
P00325	BXGT005498	Alcohol dehydrogenase 1B	125	reviewed	Enzyme
P00367	BXGT005517	Glutamate dehydrogenase 1, mitochondrial	2746	reviewed	Enzyme
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00966	BXGT005707	Argininosuccinate synthase	445	reviewed	Enzyme
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01023	BXGT005718	Alpha-2-macroglobulin	2	reviewed	Enzyme modulator
P01031	BXGT005720	Complement C5	727	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02774	BXGT005959	Vitamin D-binding protein	2638	reviewed	Transporter
P02792	BXGT005966	Ferritin light chain	2512	reviewed	Storage
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	3156	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04156	BXGT006156	Major prion protein	5621	reviewed
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04350	BXGT006193	Tubulin beta-4A chain	10382	reviewed	Cellular structure
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04745	BXGT006255	Alpha-amylase 1	278	reviewed
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05090	BXGT006311	Apolipoprotein D	347	reviewed
P05106	BXGT006315	Integrin beta-3	3690	reviewed	Receptor
P05161	BXGT006331	Ubiquitin-like protein ISG15	9636	reviewed	Nucleic acid binding
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P05937	BXGT006396	Calbindin	793	reviewed	Calcium-binding protein
P06276	BXGT006430	Cholinesterase	590	reviewed
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	1129	reviewed	G-protein coupled receptor
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	1132	reviewed	G-protein coupled receptor
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09769	BXGT006917	Tyrosine-protein kinase Fgr	2268	reviewed	Kinase
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10768	BXGT007611	S-formylglutathione hydrolase	2098	reviewed	Enzyme
P11137	BXGT007656	Microtubule-associated protein 2	4133	reviewed
P11169	BXGT007664	Solute carrier family 2, facilitated glucose transporter member 3	6515	reviewed	Transporter
P11387	BXGT007696	DNA topoisomerase 1	7150	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11498	BXGT007714	Pyruvate carboxylase, mitochondrial	5091	reviewed	Enzyme
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13497	BXGT007915	Bone morphogenetic protein 1	649	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14550	BXGT008019	Aldo-keto reductase family 1 member A1	10327	reviewed	Enzyme
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P14672	BXGT008037	Solute carrier family 2, facilitated glucose transporter member 4	6517	reviewed	Transporter
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P14920	BXGT008067	D-amino-acid oxidase	1610	reviewed
P15104	BXGT008081	Glutamine synthetase	2752	reviewed	Enzyme
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P18847	BXGT008431	Cyclic AMP-dependent transcription factor ATF-3	467	reviewed	Transcription factor
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20132	BXGT008546	L-serine dehydratase/L-threonine deaminase	10993	reviewed	Enzyme
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P20711	BXGT008594	Aromatic-L-amino-acid decarboxylase	1644	reviewed
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21333	BXGT008638	Filamin-A	2316	reviewed
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22304	BXGT008752	Iduronate 2-sulfatase	3423	reviewed
P22626	BXGT008787	Heterogeneous nuclear ribonucleoproteins A2/B1	3181	reviewed
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23416	BXGT008865	Glycine receptor subunit alpha-2	2742	reviewed	Ion channel
P23470	BXGT008872	Receptor-type tyrosine-protein phosphatase gamma	5793	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24666	BXGT008986	Low molecular weight phosphotyrosine protein phosphatase	52	reviewed
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P25325	BXGT009038	3-mercaptopyruvate sulfurtransferase	4357	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27338	BXGT009172	Amine oxidase [flavin-containing] B	4129	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	5141	reviewed
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	3351	reviewed	G-protein coupled receptor
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P28329	BXGT009251	Choline O-acetyltransferase	1103	reviewed	Enzyme
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28676	BXGT009284	Grancalcin	25801	reviewed
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P29218	BXGT009322	Inositol monophosphatase 1	3612	reviewed	Enzyme
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P30531	BXGT009432	Sodium- and chloride-dependent GABA transporter 1	6529	reviewed	Transporter
P30532	BXGT009433	Neuronal acetylcholine receptor subunit alpha-5	1138	reviewed	Ion channel
P30536	BXGT009435	Translocator protein	706	reviewed
P30559	BXGT009442	Oxytocin receptor	5021	reviewed	G-protein coupled receptor
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P31391	BXGT009535	Somatostatin receptor type 4	6754	reviewed	G-protein coupled receptor
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P32238	BXGT009611	Cholecystokinin receptor type A	886	reviewed	G-protein coupled receptor
P33981	BXGT009744	Dual specificity protein kinase TTK	7272	reviewed	Kinase
P34903	BXGT009769	Gamma-aminobutyric acid receptor subunit alpha-3	2556	reviewed	Ion channel
P34969	BXGT009777	5-hydroxytryptamine receptor 7	3363	reviewed	G-protein coupled receptor
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35408	BXGT009828	Prostaglandin E2 receptor EP4 subtype	5734	reviewed	G-protein coupled receptor
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35916	BXGT009881	Vascular endothelial growth factor receptor 3	2324	reviewed	Kinase
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36544	BXGT009926	Neuronal acetylcholine receptor subunit alpha-7	89832	reviewed
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P39086	BXGT010093	Glutamate receptor ionotropic, kainate 1	2897	reviewed	Ion channel
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P41146	BXGT010226	Nociceptin receptor	4987	reviewed	G-protein coupled receptor
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P42261	BXGT010293	Glutamate receptor 1	2890	reviewed	Ion channel
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42356	BXGT010305	Phosphatidylinositol 4-kinase alpha	5297	reviewed	Kinase
P42357	BXGT010306	Histidine ammonia-lyase	3034	reviewed
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42785	BXGT010338	Lysosomal Pro-X carboxypeptidase	5547	reviewed	Enzyme
P42858	BXGT010341	Huntingtin	3064	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43003	BXGT010347	Excitatory amino acid transporter 1	6507	reviewed	Transporter
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43005	BXGT010349	Excitatory amino acid transporter 3	6505	reviewed	Transporter
P43354	BXGT010381	Nuclear receptor subfamily 4 group A member 2	4929	reviewed	Nuclear receptor
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P46098	BXGT010507	5-hydroxytryptamine receptor 3A	3359	reviewed	Ion channel
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46597	BXGT010528	Acetylserotonin O-methyltransferase	438	reviewed
P46663	BXGT010531	B1 bradykinin receptor	623	reviewed	G-protein coupled receptor
P47869	BXGT010590	Gamma-aminobutyric acid receptor subunit alpha-2	2555	reviewed	Ion channel
P47898	BXGT010594	5-hydroxytryptamine receptor 5A	3361	reviewed	G-protein coupled receptor
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48066	BXGT010618	Sodium- and chloride-dependent GABA transporter 3	6538	reviewed	Transporter
P48067	BXGT010619	Sodium- and chloride-dependent glycine transporter 1	6536	reviewed	Transporter
P48426	BXGT010630	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	5305	reviewed	Kinase
P48506	BXGT010635	Glutamate--cysteine ligase catalytic subunit	2729	reviewed	Enzyme
P48730	BXGT010656	Casein kinase I isoform delta	1453	reviewed	Kinase
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P48775	BXGT010662	Tryptophan 2,3-dioxygenase	6999	reviewed	Enzyme
P49336	BXGT010697	Cyclin-dependent kinase 8	1024	reviewed	Kinase
P49419	BXGT010705	Alpha-aminoadipic semialdehyde dehydrogenase	501	reviewed	Enzyme
P49674	BXGT010725	Casein kinase I isoform epsilon	1454	reviewed
P49711	BXGT010728	Transcriptional repressor CTCF	10664	reviewed	Transcription factor
P49767	BXGT010739	Vascular endothelial growth factor C	7424	reviewed	Signaling
P49773	BXGT010741	Histidine triad nucleotide-binding protein 1	3094	reviewed	Enzyme
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P50406	BXGT010796	5-hydroxytryptamine receptor 6	3362	reviewed	G-protein coupled receptor
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P50579	BXGT010812	Methionine aminopeptidase 2	10988	reviewed
P51114	BXGT010832	Fragile X mental retardation syndrome-related protein 1	8087	reviewed	Nucleic acid binding
P51449	BXGT010846	Nuclear receptor ROR-gamma	6097	reviewed	Nuclear receptor
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P51649	BXGT010872	Succinate-semialdehyde dehydrogenase, mitochondrial	7915	reviewed	Enzyme
P51688	BXGT010883	N-sulphoglucosamine sulphohydrolase	6448	reviewed	Enzyme
P53985	BXGT011022	Monocarboxylate transporter 1	6566	reviewed	Transporter
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54219	BXGT011037	Chromaffin granule amine transporter	6570	reviewed	Transporter
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P54802	BXGT011081	Alpha-N-acetylglucosaminidase	4669	reviewed
P54829	BXGT011085	Tyrosine-protein phosphatase non-receptor type 5	84867	reviewed
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P55211	BXGT011111	Caspase-9	842	reviewed	Enzyme
P55212	BXGT011112	Caspase-6	839	reviewed	Enzyme
P55786	BXGT011125	Puromycin-sensitive aminopeptidase	9520	reviewed	Enzyme
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P58400	BXGT011235	Neurexin-1-beta	9378	reviewed
P60174	BXGT011294	Triosephosphate isomerase	7167	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P60903	BXGT011339	Protein S100-A10	6281	reviewed	Calcium-binding protein
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P62166	BXGT011412	Neuronal calcium sensor 1	23413	reviewed
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63098	BXGT011497	Calcineurin subunit B type 1	5534	reviewed
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P78352	BXGT011836	Disks large homolog 4	1742	reviewed	Receptor
P78563	BXGT011850	Double-stranded RNA-specific editase 1	104	reviewed	Enzyme
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q01469	BXGT012590	Fatty acid-binding protein 5	2171	reviewed
Q01668	BXGT012605	Voltage-dependent L-type calcium channel subunit alpha-1D	776	reviewed	Ion channel
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q02779	BXGT012670	Mitogen-activated protein kinase kinase kinase 10	4294	reviewed	Kinase
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q04446	BXGT012764	1,4-alpha-glucan-branching enzyme	2632	reviewed	Enzyme
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q05586	BXGT012826	Glutamate receptor ionotropic, NMDA 1	2902	reviewed	Ion channel
Q05940	BXGT012846	Synaptic vesicular amine transporter	6571	reviewed	Transporter
Q06033	BXGT012853	Inter-alpha-trypsin inhibitor heavy chain H3	3699	reviewed	Enzyme modulator
Q06710	BXGT012887	Paired box protein Pax-8	7849	reviewed
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q07343	BXGT012926	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	5142	reviewed
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07954	BXGT012950	Prolow-density lipoprotein receptor-related protein 1	4035	reviewed
Q08345	BXGT012982	Epithelial discoidin domain-containing receptor 1	780	reviewed	Kinase
Q12756	BXGT013261	Kinesin-like protein KIF1A	547	reviewed	Cellular structure
Q12879	BXGT013275	Glutamate receptor ionotropic, NMDA 2A	2903	reviewed	Ion channel
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	2898	reviewed	Ion channel
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13451	BXGT013356	Peptidyl-prolyl cis-trans isomerase FKBP5	2289	reviewed	Enzyme
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	1859	reviewed	Kinase
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q13938	BXGT013405	Calcyphosin	828	reviewed
Q13946	BXGT013406	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	5150	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q14203	BXGT013455	Dynactin subunit 1	1639	reviewed	Chaperone
Q14289	BXGT013459	Protein-tyrosine kinase 2-beta	2185	reviewed	Kinase
Q14416	BXGT013468	Metabotropic glutamate receptor 2	2912	reviewed	G-protein coupled receptor
Q14624	BXGT013491	Inter-alpha-trypsin inhibitor heavy chain H4	3700	reviewed	Enzyme modulator
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q14831	BXGT013506	Metabotropic glutamate receptor 7	2917	reviewed	G-protein coupled receptor
Q14832	BXGT013507	Metabotropic glutamate receptor 3	2913	reviewed	G-protein coupled receptor
Q14914	BXGT013513	Prostaglandin reductase 1	22949	reviewed	Enzyme
Q15047	BXGT013528	Histone-lysine N-methyltransferase SETDB1	9869	reviewed
Q15078	BXGT013534	Cyclin-dependent kinase 5 activator 1	8851	reviewed	Enzyme modulator
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15751	BXGT013593	Probable E3 ubiquitin-protein ligase HERC1	8925	reviewed	Enzyme modulator
Q15822	BXGT013602	Neuronal acetylcholine receptor subunit alpha-2	1135	reviewed	Ion channel
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16099	BXGT013620	Glutamate receptor ionotropic, kainate 4	2900	reviewed	Ion channel
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16555	BXGT013638	Dihydropyrimidinase-related protein 2	1808	reviewed	Enzyme
Q16566	BXGT013639	Calcium/calmodulin-dependent protein kinase type IV	814	reviewed	Kinase
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q2M385	BXGT014131	Macrophage-expressed gene 1 protein	219972	reviewed
Q53GQ0	BXGT015013	Very-long-chain 3-oxoacyl-CoA reductase	51144	reviewed
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q5T6L4	BXGT015848	Argininosuccinate synthase 1 isoform 1	445	unreviewed
Q5TCY1	BXGT015853	Tau-tubulin kinase 1	84630	reviewed	Kinase
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q6NYC1	BXGT016436	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	23210	reviewed	Receptor
Q6W5P4	BXGT016588	Neuropeptide S receptor	387129	reviewed
Q7LBC6	BXGT016998	Lysine-specific demethylase 3B	51780	reviewed	Epigenetic regulator
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8IWQ3	BXGT018355	Serine/threonine-protein kinase BRSK2	9024	reviewed	Kinase
Q8IZ41	BXGT018371	Ras and EF-hand domain-containing protein	158158	reviewed
Q8N0W4	BXGT018492	Neuroligin-4, X-linked	57502	reviewed
Q8NFD2	BXGT018559	Ankyrin repeat and protein kinase domain-containing protein 1	255239	reviewed	Kinase
Q8NI60	BXGT018572	Atypical kinase COQ8A, mitochondrial	56997	reviewed	Kinase
Q8TDS5	BXGT018813	Oxoeicosanoid receptor 1	165140	reviewed	G-protein coupled receptor
Q8TDV0	BXGT018815	Probable G-protein coupled receptor 151	134391	reviewed	G-protein coupled receptor
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q92796	BXGT019376	Disks large homolog 3	1741	reviewed
Q93009	BXGT019455	Ubiquitin carboxyl-terminal hydrolase 7	7874	reviewed	Enzyme
Q96C19	BXGT019630	EF-hand domain-containing protein D2	79180	reviewed	Calcium-binding protein
Q96CW9	BXGT019634	Netrin-G2	84628	reviewed	Enzyme modulator
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96FE5	BXGT019657	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	84894	reviewed	Receptor
Q96GD0	BXGT019665	Pyridoxal phosphate phosphatase	57026	reviewed	Enzyme
Q96LA8	BXGT019691	Protein arginine N-methyltransferase 6	55170	reviewed	Epigenetic regulator
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PU5	BXGT019711	E3 ubiquitin-protein ligase NEDD4-like	23327	reviewed	Enzyme
Q96RJ0	BXGT019728	Trace amine-associated receptor 1	134864	reviewed	G-protein coupled receptor
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99500	BXGT019927	Sphingosine 1-phosphate receptor 3	1903	reviewed	G-protein coupled receptor
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99581	BXGT019937	Protein FEV	54738	reviewed	Transcription factor
Q99653	BXGT019945	Calcineurin B homologous protein 1	11261	reviewed
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	3028	reviewed	Enzyme
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q99808	BXGT019964	Equilibrative nucleoside transporter 1	2030	reviewed	Transporter
Q9BQF6	BXGT020111	Sentrin-specific protease 7	57337	reviewed	Enzyme
Q9BR01	BXGT020115	Sulfotransferase 4A1	25830	reviewed
Q9BXJ9	BXGT020170	N-alpha-acetyltransferase 15, NatA auxiliary subunit	80155	reviewed	Enzyme
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9GZT4	BXGT020424	Serine racemase	63826	reviewed	Enzyme
Q9H2J7	BXGT020453	Sodium-dependent neutral amino acid transporter B(0)AT2	55117	reviewed	Transporter
Q9H2X9	BXGT020459	Solute carrier family 12 member 5	57468	reviewed	Transporter
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NPH2	BXGT021158	Inositol-3-phosphate synthase 1	51477	reviewed
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	6328	reviewed	Ion channel
Q9NZJ4	BXGT021274	Sacsin	26278	reviewed
Q9NZJ5	BXGT021275	Eukaryotic translation initiation factor 2-alpha kinase 3	9451	reviewed	Kinase
Q9NZN1	BXGT021279	Interleukin-1 receptor accessory protein-like 1	11141	reviewed	Receptor
Q9P0L2	BXGT021289	Serine/threonine-protein kinase MARK1	4139	reviewed	Kinase
Q9P2R7	BXGT021304	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	8803	reviewed	Enzyme
Q9P2W7	BXGT021306	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	27087	reviewed	Enzyme
Q9UHF0	BXGT021699	Tachykinin-3	6866	reviewed
Q9UI33	BXGT021712	Sodium channel protein type 11 subunit alpha	11280	reviewed	Ion channel
Q9UKV0	BXGT021750	Histone deacetylase 9	9734	reviewed	Epigenetic regulator
Q9UKV8	BXGT021752	Protein argonaute-2	27161	reviewed
Q9ULV1	BXGT021764	Frizzled-4	8322	reviewed	G-protein coupled receptor
Q9UN36	BXGT021780	Protein NDRG2	57447	reviewed	Enzyme
Q9UQB8	BXGT021809	Brain-specific angiogenesis inhibitor 1-associated protein 2	10458	reviewed	Receptor
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9UQL6	BXGT021813	Histone deacetylase 5	10014	reviewed	Epigenetic regulator
Q9Y233	BXGT022210	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10846	reviewed
Q9Y2D1	BXGT022230	Cyclic AMP-dependent transcription factor ATF-5	22809	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y2W7	BXGT022250	Calsenilin	30818	reviewed	Ion channel
Q9Y478	BXGT022271	5'-AMP-activated protein kinase subunit beta-1	5564	reviewed	Kinase
Q9Y5B9	BXGT022291	FACT complex subunit SPT16	11198	reviewed	Transcription factor
Q9Y5N1	BXGT022297	Histamine H3 receptor	11255	reviewed	G-protein coupled receptor
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q7Z3S7	BXGT022658	Voltage-dependent calcium channel subunit alpha-2/delta-4	93589	reviewed	Ion channel
Q9NYP7	BXGT022661	Elongation of very long chain fatty acids protein 5	60481	reviewed	Enzyme
Q92847	BXGT022673	Growth hormone secretagogue receptor type 1	2693	reviewed	G-protein coupled receptor
P35240	BXGT022927	Merlin	4771	reviewed
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
P17752	BXGT023118	Tryptophan 5-hydroxylase 1	7166	reviewed
P17535	BXGT023437	Transcription factor jun-D	3727	reviewed	Transcription factor
P53539	BXGT023438	Protein fosB	2354	reviewed	Transcription factor
P16615	BXGT023653	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	488	reviewed	Transporter
Q13007	BXGT023883	Interleukin-24	11009	reviewed
P21926	BXGT024578	CD9 antigen	928	reviewed
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator
P38646	BXGT024954	Stress-70 protein, mitochondrial	3313	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
P25090	BXGT025102	N-formyl peptide receptor 2	2358	reviewed	G-protein coupled receptor
P49366	BXGT025175	Deoxyhypusine synthase	1725	reviewed
P27918	BXGT025485	Properdin	5199	reviewed
Q96DA2	BXGT025522	Ras-related protein Rab-39B	116442	reviewed
Q05086	BXGT025648	Ubiquitin-protein ligase E3A	7337	reviewed
Q9BYC5	BXGT025656	Alpha-(1,6)-fucosyltransferase	2530	reviewed
Q7Z3B1	BXGT025707	Neuronal growth regulator 1	257194	reviewed
Q8TAB3	BXGT025819	Protocadherin-19	57526	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}