Showing entry for cGMP-specific 3',5'-cyclic phosphodiesterase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022689
Protein NamecGMP-specific 3',5'-cyclic phosphodiesterase
Uniport IdQ8CG03
GenePde5a
Gene Id242202
DomainGAF; PDEase_I
Pfam PF01590   PF00233  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046069 cGMP catabolic process
Biological Process GO:0046068 cGMP metabolic process
Biological Process GO:0055118 negative regulation of cardiac muscle contraction
Biological Process GO:0042130 negative regulation of T cell proliferation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0010613 positive regulation of cardiac muscle hypertrophy
Biological Process GO:0002678 positive regulation of chronic inflammatory response
Biological Process GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
Biological Process GO:0043406 positive regulation of MAP kinase activity
Biological Process GO:0060282 positive regulation of oocyte development
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0010749 regulation of nitric oxide mediated signal transduction
Biological Process GO:0002026 regulation of the force of heart contraction
Biological Process GO:0055119 relaxation of cardiac muscle
Biological Process GO:0007614 short-term memory
Biological Process GO:0007165 signal transduction
molecular function GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity
molecular function GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
molecular function GO:0030553 cGMP binding
molecular function GO:0004112 cyclic-nucleotide phosphodiesterase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0036634 Cgmp 345.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein