Showing entry for Centromere protein M


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022763
Protein NameCentromere protein M
Uniport IdQ9NSP4
GeneCENPM
Gene Id79019
DomainCENP-M
Pfam PF11111  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034080 CENP-A containing nucleosome assembly
cellular component GO:0000777 condensed chromosome kinetochore
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-141424 Amplification of signal from the kinetochores
R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-HSA-162582 Signal Transduction
R-HSA-1640170 Cell Cycle
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-2467813 Separation of Sister Chromatids
R-HSA-2500257 Resolution of Sister Chromatid Cohesion
R-HSA-2555396 Mitotic Metaphase and Anaphase
R-HSA-5663220 RHO GTPases Activate Formins
R-HSA-606279 Deposition of new CENPA-containing nucleosomes at the centromere
R-HSA-68877 Mitotic Prometaphase
R-HSA-68882 Mitotic Anaphase
R-HSA-68886 M Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69618 Mitotic Spindle Checkpoint
R-HSA-69620 Cell Cycle Checkpoints
R-HSA-73886 Chromosome Maintenance
R-HSA-774815 Nucleosome assembly
R-HSA-9648025 EML4 and NUDC in mitotic spindle formation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0023418 BXGD001642 leukemia Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein