Showing entry for Methylosome protein 50


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023026
Protein NameMethylosome protein 50
Uniport IdQ9BQA1
GeneWDR77
Gene Id79084
DomainWD40
Pfam PF00400  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development
Biological Process GO:0007315 pole plasm assembly
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
Biological Process GO:0000387 spliceosomal snRNP assembly
molecular function GO:0008327 methyl-CpG binding
molecular function GO:0030374 nuclear receptor transcription coactivator activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005794 Golgi apparatus
cellular component GO:0034709 methylosome
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0045495 pole plasm
Reactome
Pathway Id Pathway Name
R-HSA-191859 snRNP Assembly
R-HSA-194441 Metabolism of non-coding RNA
R-HSA-3214858 RMTs methylate histone arginines
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-4839726 Chromatin organization
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0023601 BXGD001687 Leydig Cell Tumor Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0036631 BXGD002626 Seminoma Neoplasms
C0039590 BXGD002822 Testicular Neoplasms Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C0043346 BXGD003043 Xeroderma Pigmentosum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0483368 BXGD009016 Human anaplasmosis due to Anaplasma phagocytophilum Infections; Animal Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1334274 BXGD012695 Invasive Carcinoma Neoplasms
C1654637 BXGD013484 androgen independent prostate cancer
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1955934 BXGD016614 Trichothiodystrophy Syndromes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C2937421 BXGD018162 Prostatic Hyperplasia Male Urogenital Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein