adisease

Showing entry for Seminoma

General Disease Information
BXGD Id	BXGD002626
Disease Name	Seminoma
Disease CUI Id	C0036631
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0000119 HP:0002664
Human Phenotype Ontology Term	Abnormality of the genitourinary system; Neoplasm
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14965	BXGT004117	Aurora kinase A	6790	reviewed	Kinase
O15066	BXGT004122	Kinesin-like protein KIF3B	9371	reviewed	Cellular structure
O43597	BXGT004602	Protein sprouty homolog 2	10253	reviewed	Signaling
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75387	BXGT005122	Large neutral amino acids transporter small subunit 3	8501	reviewed	Transporter
O75751	BXGT005150	Solute carrier family 22 member 3	6581	reviewed	Transporter
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04278	BXGT006182	Sex hormone-binding globulin	6462	reviewed
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05120	BXGT006319	Plasminogen activator inhibitor 2	5055	reviewed	Enzyme modulator
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06746	BXGT006496	DNA polymerase beta	5423	reviewed	Enzyme
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08100	BXGT006725	Rhodopsin	6010	reviewed	G-protein coupled receptor
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08620	BXGT006800	Fibroblast growth factor 4	2249	reviewed	Signaling
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P0CG48	BXGT007468	Polyubiquitin-C	7316	reviewed	Nucleic acid binding
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10696	BXGT007603	Alkaline phosphatase, germ cell type	251	reviewed	Enzyme
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10909	BXGT007630	Clusterin	1191	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P12830	BXGT007852	Cadherin-1	999	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P16070	BXGT008186	CD44 antigen	960	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P19440	BXGT008481	Glutathione hydrolase 1 proenzyme	2678	reviewed	Enzyme
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21583	BXGT008667	Kit ligand	4254	reviewed
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P24941	BXGT009002	Cyclin-dependent kinase 2	1017	reviewed	Kinase
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P28347	BXGT009257	Transcriptional enhancer factor TEF-1	7003	reviewed	Transcription factor
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P30279	BXGT009415	G1/S-specific cyclin-D2	894	reviewed	Enzyme modulator
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35613	BXGT009856	Basigin	682	reviewed
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36896	BXGT009940	Activin receptor type-1B	91	reviewed	Kinase
P38484	BXGT010042	Interferon gamma receptor 2	3460	reviewed	Receptor
P39748	BXGT010134	Flap endonuclease 1	2237	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P43080	BXGT010354	Guanylyl cyclase-activating protein 1	2978	reviewed
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P45973	BXGT010492	Chromobox protein homolog 5	23468	reviewed	Epigenetic regulator
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49116	BXGT010678	Nuclear receptor subfamily 2 group C member 2	7182	reviewed	Nuclear receptor
P49450	BXGT010710	Histone H3-like centromeric protein A	1058	reviewed
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	4751	reviewed	Kinase
P52209	BXGT010923	6-phosphogluconate dehydrogenase, decarboxylating	5226	reviewed	Enzyme
P53355	BXGT010985	Death-associated protein kinase 1	1612	reviewed	Kinase
P54652	BXGT011064	Heat shock-related 70 kDa protein 2	3306	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61024	BXGT011350	Cyclin-dependent kinases regulatory subunit 1	1163	reviewed	Enzyme modulator
P62979	BXGT011476	Ubiquitin-40S ribosomal protein S27a	6233	reviewed	Nucleic acid binding
P68104	BXGT011575	Elongation factor 1-alpha 1	1915	reviewed	Enzyme
P78358	BXGT011838	Cancer/testis antigen 1	246100	reviewed
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q00534	BXGT012533	Cyclin-dependent kinase 6	1021	reviewed	Kinase
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q12923	BXGT013281	Tyrosine-protein phosphatase non-receptor type 13	5783	reviewed
Q13285	BXGT013335	Steroidogenic factor 1	2516	reviewed	Nuclear receptor
Q13309	BXGT013338	S-phase kinase-associated protein 2	6502	reviewed
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13705	BXGT013393	Activin receptor type-2B	93	reviewed	Kinase
Q13733	BXGT013394	Sodium/potassium-transporting ATPase subunit alpha-4	480	reviewed	Transporter
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q15020	BXGT013522	Squamous cell carcinoma antigen recognized by T-cells 3	9733	reviewed	Nucleic acid binding
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q495A1	BXGT014764	T-cell immunoreceptor with Ig and ITIM domains	201633	reviewed
Q8NI22	BXGT018571	Multiple coagulation factor deficiency protein 2	90411	reviewed	Transporter
Q92499	BXGT019350	ATP-dependent RNA helicase DDX1	1653	reviewed
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q96GD4	BXGT019667	Aurora kinase B	9212	reviewed	Kinase
Q99527	BXGT019930	G-protein coupled estrogen receptor 1	2852	reviewed	G-protein coupled receptor
Q99828	BXGT019967	Calcium and integrin-binding protein 1	10519	reviewed
Q9BW19	BXGT020148	Kinesin-like protein KIFC1	3833	reviewed	Cellular structure
Q9NR28	BXGT021178	Diablo homolog, mitochondrial	56616	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UIQ6	BXGT021721	Leucyl-cystinyl aminopeptidase	4012	reviewed	Enzyme
Q9UJW3	BXGT021732	DNA (cytosine-5)-methyltransferase 3-like	29947	reviewed
Q9UKV0	BXGT021750	Histone deacetylase 9	9734	reviewed	Epigenetic regulator
Q9UPY3	BXGT021802	Endoribonuclease Dicer	23405	reviewed	Enzyme
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	10000	reviewed	Kinase
Q9Y263	BXGT022220	Phospholipase A-2-activating protein	9373	reviewed	Enzyme modulator
Q9Y657	BXGT022318	Spindlin-1	10927	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
Q9BQA1	BXGT023026	Methylosome protein 50	79084	reviewed
Q13185	BXGT024241	Chromobox protein homolog 3	11335	reviewed	Epigenetic regulator
P29590	BXGT024350	Protein PML	5371	reviewed
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
O14967	BXGT026127	Calmegin	1047	reviewed	Chaperone

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}