Showing entry for Ras-related protein Rab-35



                       
General Target Information
BXGT IdBXGT024296
Protein NameRas-related protein Rab-35
Uniport IdQ15286
GeneRAB35
Gene Id11021
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019882 antigen processing and presentation
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:0032456 endocytic recycling
Biological Process GO:0016197 endosomal transport
Biological Process GO:0000281 mitotic cytokinesis
Biological Process GO:0031175 neuron projection development
Biological Process GO:0048227 plasma membrane to endosome transport
Biological Process GO:0008104 protein localization
Biological Process GO:0036010 protein localization to endosome
Biological Process GO:0015031 protein transport
Biological Process GO:0032482 Rab protein signal transduction
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
cellular component GO:0098993 anchored component of synaptic vesicle membrane
cellular component GO:0031253 cell projection membrane
cellular component GO:0045334 clathrin-coated endocytic vesicle
cellular component GO:0005905 clathrin-coated pit
cellular component GO:0030665 clathrin-coated vesicle membrane
cellular component GO:0005829 cytosol
cellular component GO:0010008 endosome membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0045171 intercellular bridge
cellular component GO:0042470 melanosome
cellular component GO:0005886 plasma membrane
cellular component GO:0055038 recycling endosome membrane
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-8854214 TBC/RABGAPs
R-HSA-8873719 RAB geranylgeranylation
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein