Showing entry for Exonuclease 3'-5' domain-containing protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024569
Protein NameExonuclease 3'-5' domain-containing protein 2
Uniport IdQ9NVH0
GeneEXD2
Gene Id55218
DomainDNA_pol_A_exo1
Pfam PF01612  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000729 DNA double-strand break processing
Biological Process GO:0006302 double-strand break repair
Biological Process GO:0000724 double-strand break repair via homologous recombination
Biological Process GO:0090305 nucleic acid phosphodiester bond hydrolysis
Biological Process GO:0031297 replication fork processing
molecular function GO:0008296 3'-5'-exodeoxyribonuclease activity
molecular function GO:0008408 3'-5' exonuclease activity
molecular function GO:0000175 3'-5'-exoribonuclease activity
molecular function GO:0008852 exodeoxyribonuclease I activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0030145 manganese ion binding
molecular function GO:0003676 nucleic acid binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity
cellular component GO:0005737 cytoplasm
cellular component GO:0016021 integral component of membrane
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0005634 nucleus
cellular component GO:0090734 site of DNA damage
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004277 BXGD000266 Tooth Attrition Stomatognathic Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0525045 BXGD009255 Mood Disorders Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C2363973 BXGD017121 Chronic thromboembolic pulmonary hypertension Respiratory Tract Diseases; Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein