Showing entry for 2,6-Dimethoxy-1,4-benzoquinone


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0000514
Compound Name2,6-Dimethoxy-1,4-benzoquinone
Structure
FormulaC8H8O4
InchiKeyOLBNOBQOQZRLMP-UHFFFAOYSA-N
SMILESCOC1=CC(=O)C=C(OC)C1=O
InchiInChI=1S/C8H8O4/c1-11-6-3-5(9)4-7(12-2)8(6)10/h3-4H,1-2H3
IUPAC2,6-dimethoxycyclohexa-2,5-diene-1,4-dione
Molecular Weight168.15
Pubchem Id68262
Chembl IdCHEMBL448515
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB KIA
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q70KY3 BXGT016676 Laccase-1 reviewed LAC1 - - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL448515
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P97697 BXGT012214 Inositol monophosphatase 1 reviewed - Impa1 Potency '=' 31622 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 115 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 819 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 29092 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 25118 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 8912 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 17782 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 14125 nM
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 31622 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 35481 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 35481 nM
O97447 BXGT005436 Putative fructose-1,6-bisphosphate aldolase unreviewed - ald Potency '=' 7062 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 651 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 22387 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 7943 nM
O75604 BXGT005139 Ubiquitin carboxyl-terminal hydrolase 2 reviewed Enzyme USP2 Potency '=' 7943 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 25118 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 25118 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 17782 nM
P0DPI0 BXGT007528 Botulinum neurotoxin type A reviewed - botA Inhibition - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 2310 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 31622 nM
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 5623 nM
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 15848 nM
P43220 BXGT010367 Glucagon-like peptide 1 receptor reviewed G-protein coupled receptor GLP1R Potency - 28183 nM
Q03431 BXGT012714 Parathyroid hormone/parathyroid hormone-related peptide receptor reviewed G-protein coupled receptor PTH1R Potency - 44668 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 28183 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 28183 nM
Q57TT1 BXGT015153 Uncharacterized protein unreviewed - Tb927.8.6820 Potency - 2511 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 10000 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Potency '=' 28183 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 2818 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 5011 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 4466 nM
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase reviewed Enzyme WRN Potency - 44668 nM
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 18356 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 5173 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 22387 nM
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short reviewed - GNAS Potency - 31622 nM
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed Kinase PLK1 Potency - 5972 nM
Q2TB90 BXGT014214 Putative hexokinase HKDC1 reviewed Kinase HKDC1 IC50 '=' 3540 nM
Q2TB90 BXGT014214 Putative hexokinase HKDC1 reviewed Kinase HKDC1 IC50 '=' 2490 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 101 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 580 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00187 Common wheat Triticum aestivum Cereals and cereal products
BXGF00198 Adzuki bean Vigna angularis Pulses
BXGF00301 Cherimoya Annona cherimola Fruits
BXGF00824 Green vegetables Vegetables
BXGF00936 Tanacetum nubigenum Tanacetum nubigenum Others
BXGF00993 Dracaena concinna Dracaena concinna Others
BXGF01060 Baccharis grandicapitulata Baccharis grandicapitulata Others
BXGF01079 Renealmia alpinia Renealmia alpinia Human Edible Plant
BXGF01091 Rubus alceifolius Rubus alceifolius Human Edible Plant
BXGF01207 Morella pensylvanica Morella pensylvanica Others
BXGF01227 Cyperus capitatus Cyperus capitatus Others
BXGF01276 Delphinium giraldii Delphinium giraldii Medicinal Plant
BXGF01337 Stellaria media Stellaria media Medicinal Plant
BXGF01384 Litsea nitida Litsea nitida Others
BXGF01493 Curcuma aeruginosa Curcuma aeruginosa Medicinal Plant
BXGF01559 Achillea wilhelmsii Achillea wilhelmsii Others
BXGF01603 Piper brachystachyum Piper brachystachyum Medicinal Plant
BXGF01637 Gynura segetum Gynura segetum Medicinal Plant
BXGF01667 Tripterygium wilfordii Tripterygium wilfordii Medicinal Plant
BXGF01688 Tephroseris kirilowii Tephroseris kirilowii Medicinal Plant
BXGF01818 Ophiorrhiza kuroiwae Ophiorrhiza kuroiwae Others
BXGF01934 Delphinium tricorne Delphinium tricorne Others
BXGF01967 Senecio congestus Senecio congestus Medicinal Plant
BXGF02014 Jatropha gossypiifolia Jatropha gossypiifolia Medicinal Plant
BXGF02023 Tamarix dioica Tamarix dioica Medicinal Plant
BXGF02077 Boronia alata Boronia alata Others
BXGF02102 Lobelia langeana Lobelia langeana Others
BXGF02124 Papaver pseudocanescens Papaver pseudocanescens Others
BXGF02154 Sassafras officinalis Sassafras officinalis Others
BXGF02225 Backhousia angustifolia Backhousia angustifolia Others
BXGF02226 Helleborus viridis Helleborus viridis Medicinal Plant
BXGF02242 Sideritis dasygnaphala Sideritis dasygnaphala Others
BXGF02248 Juniperus ashei Juniperus ashei Medicinal Plant
BXGF02271 Xanthium canadense Xanthium canadense Medicinal Plant
BXGF02324 Iris sibirica Iris sibirica Medicinal Plant
BXGF02382 Gutierrezia dracunculoides Gutierrezia dracunculoides Others
BXGF02391 Haemanthus albiflos Haemanthus albiflos Medicinal Plant
BXGF02413 Sibiraea angustata Sibiraea angustata Others
BXGF02423 Psidium acutangulum Psidium acutangulum Human Edible Plant
BXGF02440 Beesia calthifolia Beesia calthifolia Others
BXGF02444 Valeriana officinalis Valeriana officinalis Medicinal Plant
BXGF02453 Cunninghamia lanceolata var. konishii Cunninghamia lanceolata var. konishii Others
BXGF02467 Peltophorum dubium Peltophorum dubium Others
BXGF02482 Isodon amethystoides Isodon amethystoides Medicinal Plant
BXGF02483 Bursera kerberi Bursera kerberi Others
BXGF02501 Hordeum bulbosum Hordeum bulbosum Medicinal Plant
BXGF02514 Helenium integrifolium Helenium integrifolium Others
BXGF02532 Dioscorea villosa Dioscorea villosa Medicinal Plant
BXGF02543 Rhododendron mucronulatum Rhododendron mucronulatum Medicinal Plant
BXGF02570 Euonymus fortunei Euonymus fortunei Medicinal Plant
BXGF02580 Agathis lanceolata Agathis lanceolata Human Edible Plant
BXGF02584 Magnolia henryi Magnolia henryi Others
BXGF02613 Phlomis crinita Phlomis crinita Medicinal Plant
BXGF02628 Micromelum falcatum Micromelum falcatum Human Edible Plant
BXGF02660 Eria siamensis Eria siamensis Others
BXGF02665 Crotalaria stolzii Crotalaria stolzii Others
BXGF02682 Selinum libanotis Selinum libanotis Others
BXGF02700 Prunus pseudocerasus Prunus pseudocerasus Medicinal Plant
BXGF02714 Vernonia aurea Vernonia aurea Others
BXGF02718 Melampodium leucanthum Melampodium leucanthum Others
BXGF02734 Clerodendrum trichotomum Clerodendrum trichotomum Medicinal Plant
BXGF02750 Juniperus scopulorum Juniperus scopulorum Medicinal Plant
BXGF02785 Clinacanthus nutans Clinacanthus nutans Medicinal Plant
BXGF02799 Betula papyrifera Betula papyrifera Medicinal Plant
BXGF02827 Alstonia angustiloba Alstonia angustiloba Others
BXGF02840 Lasianthaea podocephala Lasianthaea podocephala Others
BXGF02855 Eucalyptus albens Eucalyptus albens Others
BXGF02873 Ephedra altissima Ephedra altissima Medicinal Plant
BXGF02894 Bignonia unguiscati Bignonia unguiscati Others
BXGF02904 Coronilla hyrcana Coronilla hyrcana Others
BXGF02908 Pellacalyx axillaris Pellacalyx axillaris Others
BXGF02921 Erica cinerea Erica cinerea Medicinal Plant
BXGF02943 Maytenus emarginata Maytenus emarginata Others
BXGF02950 Boschniakia rossica Boschniakia rossica Medicinal Plant
BXGF03817 Coffea liberica var. dewevrei Coffea liberica var. dewevrei Medicinal Plant
BXGF04011 Botrychium ternatum Botrychium ternatum Medicinal Plant
BXGF04902 Lupinus cosentinii Lupinus cosentinii Others
BXGF05127 Robinia pseudoacacia Robinia pseudoacacia Medicinal Plant
BXGF05194 Acacia salicina Acacia salicina Medicinal Plant
BXGF05196 Neolitsea pulchella Neolitsea pulchella Medicinal Plant
BXGF05232 Isolona pilosa Isolona pilosa Others
BXGF05318 Hedysarum gmelini Hedysarum gmelini Others
BXGF05465 Euploca racemosa Euploca racemosa Others
BXGF05677 Cinnamomum philippinense Cinnamomum philippinense Human Edible Plant
BXGF05710 Blighia welwitschii Blighia welwitschii Human Edible Plant
BXGF05822 Salvia miniata Salvia miniata Others
BXGF06162 Aeschynanthus parvifolius Aeschynanthus parvifolius Others
BXGF06240 Kalanchoe blossfeldiana Kalanchoe blossfeldiana Others
BXGF06268 Zanthoxylum nitidum Zanthoxylum nitidum Medicinal Plant
BXGF06269 Fraxinus szaboana Fraxinus szaboana Medicinal Plant
BXGF06271 Artemisia pectinata Artemisia pectinata Others
BXGF06307 Zephyranthes flava Zephyranthes flava Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease