Showing entry for 2-Hydroxy-6-pentadecylbenzoic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0000523
Compound Name2-Hydroxy-6-pentadecylbenzoic acid
Structure
FormulaC22H36O3
InchiKeyADFWQBGTDJIESE-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCCCCC1=CC=CC(O)=C1C(O)=O
InchiInChI=1S/C22H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h15,17-18,23H,2-14,16H2,1H3,(H,24,25)
IUPAC2-hydroxy-6-pentadecylbenzoic acid
Molecular Weight348.52
Pubchem Id167551
Chembl IdCHEMBL33778
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50240436
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT013038 Histone acetyltransferase p300 reviewed EP300 - 8500 - -
reviewed BXGT019380 Histone acetyltransferase KAT2B reviewed KAT2B - 5000 - -
reviewed BXGT019380 Histone acetyltransferase KAT2B reviewed KAT2B - 33900 - -
reviewed BXGT013038 Histone acetyltransferase p300 reviewed EP300 - 4150 - -
reviewed BXGT006736 Seed linoleate 13S-lipoxygenase-1 reviewed LOX1.1 - 85000 - -
reviewed BXGT006736 Seed linoleate 13S-lipoxygenase-1 reviewed LOX1.1 - 51900 - -
reviewed BXGT014587 Probable linoleate 9S-lipoxygenase 5 reviewed LOX1.5 - 43000 - -
reviewed BXGT021651 SUMO-activating enzyme subunit 1 reviewed Enzyme SAE1 - 2200 - -
CHEMBL CHEMBL33778
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 Vmax '=' 12 pmol/min
P08170 BXGT006736 Seed linoleate 13S-lipoxygenase-1 reviewed - LOX1.1 Inhibition '=' 50 %
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Inhibition '<' 50 %
P09917 BXGT006941 Arachidonate 5-lipoxygenase reviewed Enzyme ALOX5 Inhibition - - -
Q43191 BXGT014587 Probable linoleate 9S-lipoxygenase 5 reviewed - LOX1.5 IC50 '=' 43000 nM
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 K0.5 '=' 47 uM
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B IC50 '=' 33900 nM
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B IC50 '=' 5000 nM
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B Inhibition '=' 3 %
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 logIC50 '=' 2 -
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 Km '=' 2400 nM
Q9UBE0 BXGT021651 SUMO-activating enzyme subunit 1 reviewed Enzyme SAE1 IC50 '=' 2200 nM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 IC50 '=' 8500 nM
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 Km '=' 1000 nM
Q43191 BXGT014587 Probable linoleate 9S-lipoxygenase 5 reviewed - LOX1.5 Inhibition '=' 50 %
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 Vmax '=' 6 pmol/min
P08170 BXGT006736 Seed linoleate 13S-lipoxygenase-1 reviewed - LOX1.1 IC50 '=' 51900 nM
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B Inhibition '<' 10 %
Q43191 BXGT014587 Probable linoleate 9S-lipoxygenase 5 reviewed - LOX1.5 Inhibition '=' 30 %
P08170 BXGT006736 Seed linoleate 13S-lipoxygenase-1 reviewed - LOX1.1 IC50 '=' 85000 nM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 Inhibition '=' 97 %
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 Km '=' 1900 nM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 IC50 '=' 4150 nM
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 K0.5 '=' 514 uM
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 Inhibition '>' 50 %
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 Ki '=' 64000 nM
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 K0.5 '=' 54 uM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 %max '=' 60 %
Q92993 BXGT019403 Histone acetyltransferase KAT5 reviewed - KAT5 IC50 '=' 64000 nM
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 IC50 '=' 43000 nM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 INH '=' 8 uM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 Inhibition - - -
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 reviewed - KAT8 Vmax '=' 9 pmol/min
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00011 Cashew nut Anacardium occidentale Nuts
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00369 Sacred lotus Nelumbo nucifera Vegetables
BXGF00816 Fats and oils Fats and oils
BXGF01401 Aronia arbutifolia Aronia arbutifolia Medicinal Plant
BXGF01520 Viscaria viscosa Viscaria viscosa Others
BXGF01532 Clibadium mexiae Clibadium mexiae Others
BXGF02268 Ginkgo semen Ginkgo semen Others
BXGF02469 Discaria serratifolia Discaria serratifolia Others
BXGF05097 Pteris dactylina Pteris dactylina Medicinal Plant
BXGF06172 Pyrostegia venusta Pyrostegia venusta Others
BXGF06324 Justicia hayatai Justicia hayatai Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease