acompound

Showing entry for 1,2,3,4-Tetrahydro-2-methyl-b-carboline

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0000653
Compound Name	1,2,3,4-Tetrahydro-2-methyl-b-carboline
Structure
Formula	C12H14N2
InchiKey	JOFKCNJIUXPJAC-UHFFFAOYSA-N
SMILES	CN1CCC2=C(C1)NC1=C2C=CC=C1
Inchi	InChI=1S/C12H14N2/c1-14-7-6-10-9-4-2-3-5-11(9)13-12(10)8-14/h2-5,13H,6-8H2,1H3
IUPAC	2-methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indole
Molecular Weight	186.25
Pubchem Id	121896
Chembl Id	CHEMBL69618

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT011180	Amine oxidase [flavin-containing] B	reviewed		MAOB	400000	-	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P23977	BXGT008936	Sodium-dependent dopamine transporter	reviewed	-	Slc6a3	DA release	'='	19	%
P56560	BXGT011180	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	Rate of oxidation	'='	0	nM min-1 ml-1
P04062	BXGT006140	Lysosomal acid glucosylceramidase	reviewed	-	GBA	Potency	-	39810	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	39810	nM
P56560	BXGT011180	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	Ki	'='	400000	nM
P23977	BXGT008936	Sodium-dependent dopamine transporter	reviewed	-	Slc6a3	DA release	'='	1	%
P27338	BXGT009172	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	Relative activity	'='	2	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	Relative activity	'='	2	-
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	100000	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	819	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00823	Fruits		Fruits
BXGF04341	Sanguisorba officinalis	Sanguisorba officinalis	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}