Showing entry for Udp-glucose


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003416
Compound NameUdp-glucose
Structure
FormulaC15H24N2O17P2
InchiKeyHSCJRCZFDFQWRP-JZMIEXBBSA-N
SMILESOC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O
InchiInChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
IUPAC[({[(2S,3R,4S,5S)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})phosphinic acid
Molecular Weight566.3
Pubchem Id8629
Chembl IdCHEMBL375951
Targets of Information Source
DrugBank DB01861
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Q8KN66 BXGT018435 WbpP unreviewed - - experimental -
P46976 BXGT010558 Glycogenin-1 reviewed Enzyme GYG1 experimental -
P31677 BXGT009568 Trehalose-6-phosphate synthase reviewed - otsA experimental -
P09148 BXGT006861 Galactose-1-phosphate uridylyltransferase reviewed - galT experimental -
Q14376 BXGT013464 UDP-glucose 4-epimerase reviewed - GALE experimental -
P26393 BXGT009110 Glucose-1-phosphate thymidylyltransferase reviewed - rmlA experimental -
P09147 BXGT006860 UDP-glucose 4-epimerase reviewed - galE experimental -
P04547 BXGT006227 DNA beta-glucosyltransferase reviewed - bgt experimental -
Q7Z4J2 BXGT017256 Putative glycosyltransferase 6 domain-containing protein 1 reviewed - GLT6D1 experimental -
PDB UPG
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P09147 BXGT006860 UDP-glucose 4-epimerase reviewed galE - - - - -
Q14376 BXGT013464 UDP-glucose 4-epimerase reviewed GALE - - - - -
P14769 BXGT008050 N-acetyllactosaminide alpha-1,3-galactosyltransferase reviewed GGTA1 - - - - -
P09148 BXGT006861 Galactose-1-phosphate uridylyltransferase reviewed galT - - - - -
O48917 BXGT004649 UDP-sulfoquinovose synthase, chloroplastic reviewed SQD1 - - - - -
P26393 BXGT009110 Glucose-1-phosphate thymidylyltransferase reviewed rmlA - - - - -
P04547 BXGT006227 DNA beta-glucosyltransferase reviewed bgt - - - - -
P13280 BXGT007897 Glycogenin-1 reviewed GYG1 - - - - -
A0A6C6YZ99 BXGT022683 Glucose-1-phosphate thymidylyltransferase unreviewed SPAB_00935 - - - - -
P08037 BXGT006717 Beta-1,4-galactosyltransferase 1 reviewed B4GALT1 - - - - -
Q8KN66 BXGT018435 WbpP unreviewed - - - - -
P31677 BXGT009568 Trehalose-6-phosphate synthase reviewed otsA - - - - -
P04519 BXGT006223 DNA alpha-glucosyltransferase reviewed agt - - - - -
P04397 BXGT006205 Bifunctional protein GAL10 reviewed GAL10 - - - - -
Q5IFH7 BXGT015427 Glycosyltransferase unreviewed 11410948 - - - - -
P27115 BXGT009156 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase reviewed MGAT1 - - - - -
O25511 BXGT004255 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) reviewed pseB - - - - -
Q9M9P3 BXGT021107 UTP--glucose-1-phosphate uridylyltransferase 2 reviewed UGP2 - - - - -
Q4QDU3 BXGT014873 UTP--glucose-1-phosphate uridylyltransferase unreviewed UGP - - - - -
Q89399 BXGT017736 UDP-Glucose glycosyltransferase unreviewed A064R - - - - -
O60701 BXGT004894 UDP-glucose 6-dehydrogenase reviewed UGDH - - - - -
Q46342 BXGT014636 Cytotoxin L unreviewed - - - - -
Q5WWY0 BXGT015903 Uncharacterized protein unreviewed lpl1319 - - - 100 -
O58762 BXGT004812 Trehalose synthase reviewed treT - - - - -
Q73WU1 BXGT016789 Glucosyl-3-phosphoglycerate synthase reviewed MAP_2569c - - - - -
Q3JPI3 BXGT014458 UDP-glucose 4-epimerase unreviewed galE - - - - -
Q48485 BXGT014748 UDP-galactopyranose mutase reviewed rfbD - - - 750000 -
Q388T4 BXGT014353 UTP--glucose-1-phosphate uridylyltransferase unreviewed Tb10.389.0330 - - - - -
Q5WWY0 BXGT015903 Uncharacterized protein unreviewed lpl1319 - - - - -
O25363 BXGT004251 UTP--glucose-1-phosphate uridylyltransferase unreviewed HP_0646 - - - - -
D3G6S4 BXGT002881 UDP-sugar pyrophosphorylase unreviewed USP - - - - -
P46976 BXGT010558 Glycogenin-1 reviewed GYG1 Enzyme - - - -
Q189K5 BXGT013731 Toxin A unreviewed tcdA - - - - -
A1RUM9 BXGT001036 UDP-glucose 6-dehydrogenase unreviewed Pisl_1505 - - - - -
P33038 BXGT009691 UDP-N-acetylglucosamine 1-carboxyvinyltransferase reviewed murA - - - - -
O60701 BXGT004894 UDP-glucose 6-dehydrogenase reviewed UGDH - - - 33000 -
Q9AGY4 BXGT020064 Glucose-1-phosphate thymidylyltransferase unreviewed rmlA - - - - -
C8VAU8 BXGT002625 UDP-glucose 4-epimerase (Eurofung) unreviewed ANIA_04727 - - - - -
Q16851 BXGT013682 UTP--glucose-1-phosphate uridylyltransferase reviewed UGP2 - - - - -
Q3U4G3 BXGT014527 Xyloside xylosyltransferase 1 reviewed Xxylt1 - - - - -
Q8YQW3 BXGT019137 Alr3699 protein unreviewed alr3699 - - - - -
P9WMW9 BXGT012400 Glucosyl-3-phosphoglycerate synthase reviewed gpgS - - - - -
Q9WYX9 BXGT022008 UDP-glucose 4-epimerase, putative unreviewed TM_0509 - - - - -
P16442 BXGT008227 Histo-blood group ABO system transferase reviewed ABO Enzyme - - - -
Q06321 BXGT012872 Sterol 3-beta-glucosyltransferase reviewed ATG26 - - - - -
A0A2D0TCJ6 BXGT023075 UGGT unreviewed - - - - -
Q92410 BXGT019347 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] reviewed TPS1 - - - - -
A4JT02 BXGT001242 UTP--glucose-1-phosphate uridylyltransferase unreviewed Bcep1808_6508 - - - - -
A5U1Q6 BXGT001356 Uncharacterized protein unreviewed MRA_1217 - - - - -
Q9BRQ3 BXGT020117 Uridine diphosphate glucose pyrophosphatase reviewed NUDT22 - - - - -
G0SB58 BXGT003401 UDP-glucose-glycoprotein glucosyltransferase-like protein unreviewed CTHT_0048990 - - - - -
E8MF10 BXGT024565 UDP-glucose 4-epimerase reviewed lnpD - - - - -
X2KZJ9 BXGT024343 UTP--glucose-1-phosphate uridylyltransferase unreviewed galU - - - - -
A0A003 BXGT024705 MoeE5 unreviewed moeE5 - - - - -
K7NBW3 BXGT024756 Glycosyltransferase unreviewed UDPG1 - - - - -
A0A0A1HA03 BXGT024776 UDP-glycosyltransferase 708C1 reviewed UGT708C1 - - - - -
Binding DB 50209659
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT010240 P2Y purinoceptor 2 reviewed G-protein coupled receptor P2RY2 - - - 10000
reviewed BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 - - - 400000
reviewed BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 - - - 350
reviewed BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 - - - 261
reviewed BXGT013533 P2Y purinoceptor 6 reviewed G-protein coupled receptor P2RY6 - - - 1600
reviewed BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 - - - 400
reviewed BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 - - - 354
CHEMBL CHEMBL375951
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q15391 BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 EC50 '=' 354 nM
Q15077 BXGT013533 P2Y purinoceptor 6 reviewed G-protein coupled receptor P2RY6 EC50 '=' 1600 nM
Q15391 BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 EC50 '=' 261 nM
Q15391 BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 EC50 '=' 350 nM
P41231 BXGT010240 P2Y purinoceptor 2 reviewed G-protein coupled receptor P2RY2 Activity - - -
Q15391 BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 EC50 '=' 400000 nM
P41231 BXGT010240 P2Y purinoceptor 2 reviewed G-protein coupled receptor P2RY2 EC50 '=' 10000 nM
Q15391 BXGT013565 P2Y purinoceptor 14 reviewed G-protein coupled receptor P2RY14 EC50 '=' 400 nM
Q13304 BXGT013337 Uracil nucleotide/cysteinyl leukotriene receptor reviewed G-protein coupled receptor GPR17 Activity - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00085 Soy bean Glycine max Soy
BXGF02965 Arabidopsis thaliana Arabidopsis thaliana Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease