Showing entry for Glycogenin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010558
Protein NameGlycogenin-1
Uniport IdP46976
GeneGYG1
Gene Id2992
DomainGlyco_transf_8
Pfam PF01501  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00500 Starch and sucrose metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005978 glycogen biosynthetic process
Biological Process GO:0043312 neutrophil degranulation
molecular function GO:0008466 glycogenin glucosyltransferase activity
molecular function GO:0030145 manganese ion binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0102751 UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity
cellular component GO:0005829 cytosol
cellular component GO:0005576 extracellular region
cellular component GO:1904813 ficolin-1-rich granule lumen
cellular component GO:0043202 lysosomal lumen
cellular component GO:0016020 membrane
cellular component GO:0034774 secretory granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1430728 Metabolism
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-3229121 Glycogen storage diseases
R-HSA-3322077 Glycogen synthesis
R-HSA-3785653 Myoclonic epilepsy of Lafora
R-HSA-3814836 Glycogen storage disease type XV (GYG1)
R-HSA-3828062 Glycogen storage disease type 0 (muscle GYS1)
R-HSA-5357609 Glycogen storage disease type II (GAA)
R-HSA-5663084 Diseases of carbohydrate metabolism
R-HSA-5668914 Diseases of metabolism
R-HSA-6798695 Neutrophil degranulation
R-HSA-70221 Glycogen breakdown (glycogenolysis)
R-HSA-70221 Glycogen breakdown (glycogenolysis)
R-HSA-71387 Metabolism of carbohydrates
R-HSA-71387 Metabolism of carbohydrates
R-HSA-8982491 Glycogen metabolism
R-HSA-8982491 Glycogen metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017495 BXGD001111 Gerstmann-Straussler-Scheinker Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infections; Nervous System Diseases
C0017919 BXGD001150 Glycogen Storage Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0029438 BXGD002148 Massive Osteolyses Musculoskeletal Diseases
C0030252 BXGD002199 Palpitations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0030552 BXGD002238 Paresis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042510 BXGD002987 Ventricular Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042514 BXGD002989 Tachycardia, Ventricular Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042571 BXGD002991 Vertigo Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085615 BXGD003206 Right bundle branch block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0231807 BXGD004524 Dyspnea on exertion Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0311394 BXGD006884 Difficulty walking Pathological Conditions, Signs and Symptoms
C0340279 BXGD007314 Ventricular hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0342751 BXGD007542 Generalized glycogen storage disease of infants Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0344424 BXGD007669 Ventricular Arrhythmia by ECG Finding
C0344955 BXGD007710 Ventricular septal hypertrophy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0427063 BXGD008602 Shoulder girdle weakness
C0520886 BXGD009118 ST segment elevation (finding) Cardiovascular Diseases
C0520888 BXGD009120 Inverted T wave Cardiovascular Diseases
C0541794 BXGD009262 Skeletal muscle atrophy
C0741933 BXGD010046 cardiac symptom
C0751783 BXGD010592 Lafora Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1305855 BXGD012348 Body mass index
C1404521 BXGD013022 Limb-girdle myopathy
C1533847 BXGD013318 Disorder of skeletal muscle Musculoskeletal Diseases; Nervous System Diseases
C1698196 BXGD013513 Muscle Weakness Upper Limb Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1837108 BXGD014199 Decreased muscle mass
C1843637 BXGD014597 Neck flexor weakness
C1854494 BXGD015409 Slow progression
C1858127 BXGD015775 Limb-girdle muscle weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1861403 BXGD016045 Variable expressivity
C1866141 BXGD016379 Foot dorsiflexor weakness
C1883529 BXGD016597 Ventricular Arrhythmia, CTCAE 3.0
C3150754 BXGD018334 GLYCOGEN STORAGE DISEASE XV
C3160712 BXGD018467 Palpitations, CTCAE
C4015452 BXGD020206 POLYGLUCOSAN BODY MYOPATHY 2
C4021527 BXGD020654 Abdominal wall muscle weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C4021726 BXGD020735 EMG: myopathic abnormalities Musculoskeletal Diseases; Nervous System Diseases
C4022492 BXGD020907 Increased mitochondrial number
C4022979 BXGD021052 Decreased muscle glycogen content
C4227331 BXGD022290 Cardiomyocyte hypertrophy
C4553764 BXGD023550 Ventricular Arrhythmia, CTCAE 5.0
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0003416 Udp-glucose 566.3
BXGC0003705 Chloride 35.45
BXGC0003993 Uridine diphosphate 404.16
BXGC0005625 alpha-D-Glucopyranose 180.16
BXGC0035544 1,5-anhydroglucitol 164.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein