acompound

Showing entry for Dimethyl sulfone

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0003761
Compound Name	Dimethyl sulfone
Structure
Formula	C2H6O2S
InchiKey	HHVIBTZHLRERCL-UHFFFAOYSA-N
SMILES	CS(C)(=O)=O
Inchi	InChI=1S/C2H6O2S/c1-5(2,3)4/h1-2H3
IUPAC	methanesulfonylmethane
Molecular Weight	94.13
Pubchem Id	6213
Chembl Id	CHEMBL25028

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT009662	Choline O-acetyltransferase	reviewed		Chat	28000000	-	-	-
reviewed	BXGT009662	Choline O-acetyltransferase	reviewed		Chat	260000000	-	-	-
reviewed	BXGT019743	Protein cereblon	reviewed	Enzyme	CRBN	-	181000000	-	-
reviewed	BXGT019743	Protein cereblon	reviewed	Enzyme	CRBN	137490000	-	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q13951	BXGT013407	Core-binding factor subunit beta	reviewed	-	CBFB	Potency	-	25118	nM
Q01196	BXGT012575	Runt-related transcription factor 1	reviewed	Transcription factor	RUNX1	Potency	-	25118	nM
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	115	%
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	19952	nM
Q96SW2	BXGT019743	Protein cereblon	reviewed	Enzyme	CRBN	Ki	'='	137490000	nM
A4TVL0	BXGT001255	Cereblon isoform 4	unreviewed	-	MGR_0879	IC50	'='	10000000	nM
A4TVL0	BXGT001255	Cereblon isoform 4	unreviewed	-	MGR_0879	IC50	'='	737000000	nM
P32738	BXGT009662	Choline O-acetyltransferase	reviewed	-	Chat	Ki	'='	260000000	nM
A4TVL0	BXGT001255	Cereblon isoform 4	unreviewed	-	MGR_0879	Ki	'='	664460000	nM
P32738	BXGT009662	Choline O-acetyltransferase	reviewed	-	Chat	Ki	'='	28000000	nM
A4TVL0	BXGT001255	Cereblon isoform 4	unreviewed	-	MGR_0879	Ki	'='	5690000	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	39810	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	102	%
Q96SW2	BXGT019743	Protein cereblon	reviewed	Enzyme	CRBN	IC50	'='	181000000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00097	Sweet bay	Laurus nobilis	Herbs and Spices
BXGF00150	Guava	Psidium guajava	Fruits
BXGF00872	Equisetum hyemale	Equisetum hyemale	Medicinal Plant
BXGF01185	Aloe vera	Aloe vera	Medicinal Plant
BXGF01900	Aloe ferox	Aloe ferox	Medicinal Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF04631	Aloe spicata	Aloe spicata	Medicinal Plant
BXGF04691	Oroxylum indicum	Oroxylum indicum	Medicinal Plant
BXGF04812	Meconopsis punicea	Meconopsis punicea	Medicinal Plant
BXGF04817	Euonymus alatus	Euonymus alatus	Medicinal Plant
BXGF04873	Papaver bracteatum	Papaver bracteatum	Medicinal Plant
BXGF04926	Aloe africana	Aloe africana	Medicinal Plant
BXGF04963	Equisetum hiemale	Equisetum hiemale	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}