Showing entry for 2-Biphenylol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0004719
Compound Name2-Biphenylol
Structure
FormulaC12H10O
InchiKeyLLEMOWNGBBNAJR-UHFFFAOYSA-N
SMILESOC1=CC=CC=C1C1=CC=CC=C1
InchiInChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H
IUPAC2-phenylphenol
Molecular Weight170.21
Pubchem Id7017
Chembl IdCHEMBL108829
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB CH9
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
O06647 BXGT003987 2-hydroxybiphenyl-3-monooxygenase unreviewed hbpA - - - - -
Binding DB 50308551
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT012941 Bcl-2-like protein 1 reviewed Signaling BCL2L1 - - 2700000 -
CHEMBL CHEMBL108829
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 398107 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 31622 nM
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 316227 nM
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity '=' 0 pm/min/mg
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 14 pm/min/mg
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity '=' 4 pm/min/mg
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 70794 nM
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 305 pm/min/mg
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 31622 nM
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 501187 nM
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 reviewed - UGT1A7 Activity '=' 12 pm/min/mg
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 8912 nM
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 39810 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 446683 nM
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency - 281838 nM
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency - 251188 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 1122018 nM
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 50118 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 251188 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Potency - 794328 nM
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 reviewed - UGT1A4 Activity '=' 5 pm/min/mg
O75795 BXGT005152 UDP-glucuronosyltransferase 2B17 reviewed - UGT2B17 Activity '=' 7 pm/min/mg
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 1258925 nM
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit reviewed Transcription factor NFKB1 Potency - 251188 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 35481 nM
Q07817 BXGT012941 Bcl-2-like protein 1 reviewed Signaling BCL2L1 Kd '=' 2700000 nM
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha reviewed Nuclear receptor PPARA Potency - 251188 nM
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 31622 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 501187 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 35481 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 17782 nM
P54855 BXGT011088 UDP-glucuronosyltransferase 2B15 reviewed - UGT2B15 Activity '=' 0 pm/min/mg
P49902 BXGT010758 Cytosolic purine 5'-nucleotidase reviewed Enzyme NT5C2 Inhibition '=' 19 %
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 290 pm/min/mg
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 30637 nM
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency - 446683 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 42163 nM
P00489 BXGT005553 Glycogen phosphorylase, muscle form reviewed - PYGM Activity - - -
P0DTE4 BXGT022286 UDP-glucuronosyltransferase 2A1 reviewed - UGT2A1 Activity '=' 130 pm/min/mg
O75795 BXGT005152 UDP-glucuronosyltransferase 2B17 reviewed - UGT2B17 Activity '=' 5 pm/min/mg
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 281838 nM
P35503 BXGT009840 UDP-glucuronosyltransferase 1-3 reviewed - UGT1A3 Activity '=' 94 pm/min/mg
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 1122018 nM
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 25118 nM
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 501187 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 398107 nM
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 891250 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00054 Lemon Citrus limon Fruits
BXGF00194 Lingonberry Vaccinium vitis-idaea Fruits
BXGF01065 Artemisia capillaris Artemisia capillaris Medicinal Plant
BXGF03479 Bombax ceiba Bombax ceiba Medicinal Plant
BXGF04087 Erysimum odoratum Erysimum odoratum Others
BXGF04092 Heterotheca inuloides Heterotheca inuloides Medicinal Plant
BXGF04098 Delphinium andersoni Delphinium andersoni Others
BXGF04126 Vismia jefensis Vismia jefensis Others
BXGF04142 Angelica tarokoensis Angelica tarokoensis Others
BXGF04147 Swertia delavayi Swertia delavayi Others
BXGF04165 Epimedium davidii Epimedium davidii Medicinal Plant
BXGF04168 Globba malaccensis Globba malaccensis Medicinal Plant
BXGF04175 Diphasia angolensis Diphasia angolensis Others
BXGF04182 Knightia excelsa Knightia excelsa Medicinal Plant
BXGF04199 Isodon japonicus Isodon japonicus Medicinal Plant
BXGF04207 Solanum acaule Solanum acaule Others
BXGF04216 Frullania tamarisci Frullania tamarisci Others
BXGF04221 Alangium premnifolium Alangium premnifolium Others
BXGF04233 Saussurea carthamoides Saussurea carthamoides Others
BXGF04250 Galenia africana Galenia africana Medicinal Plant
BXGF04264 Micromeria pineolens Micromeria pineolens Others
BXGF04269 Gnidia lamprantha Gnidia lamprantha Medicinal Plant
BXGF04276 Ilex amara Ilex amara Others
BXGF04295 Leonurus glaucescens Leonurus glaucescens Medicinal Plant
BXGF04342 Salacia madagascariensis Salacia madagascariensis Human Edible Plant
BXGF04343 Maba buxifolia Maba buxifolia Medicinal Plant
BXGF04777 Quercus sessiliflora Quercus sessiliflora Others
BXGF05480 Lepidium draba Lepidium draba Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease