Showing entry for UDP-glucuronosyltransferase 1-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008753
Protein NameUDP-glucuronosyltransferase 1-1
Uniport IdP22309
GeneUGT1A1
Gene Id54658
DomainUDPGT
Pfam PF00201  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00040 Pentose and glucuronate interconversions
1. Metabolism 1.1 Carbohydrate metabolism hsa00053 Ascorbate and aldarate metabolism
1. Metabolism 1.3 Lipid metabolism hsa00140 Steroid hormone biosynthesis
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00830 Retinol metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00860 Porphyrin and chlorophyll metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
6. Human Diseases 6.1 Cancers: Overview hsa05204 Chemical carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006953 acute-phase response
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0006789 bilirubin conjugation
Biological Process GO:0070980 biphenyl catabolic process
Biological Process GO:0052695 cellular glucuronidation
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0071361 cellular response to ethanol
Biological Process GO:0071385 cellular response to glucocorticoid stimulus
Biological Process GO:0017144 drug metabolic process
Biological Process GO:0008210 estrogen metabolic process
Biological Process GO:0051552 flavone metabolic process
Biological Process GO:0052696 flavonoid glucuronidation
Biological Process GO:0042167 heme catabolic process
Biological Process GO:0046483 heterocycle metabolic process
Biological Process GO:0001889 liver development
Biological Process GO:2001030 negative regulation of cellular glucuronidation
Biological Process GO:0045922 negative regulation of fatty acid metabolic process
Biological Process GO:1904224 negative regulation of glucuronosyltransferase activity
Biological Process GO:0045939 negative regulation of steroid metabolic process
Biological Process GO:0042493 response to drug
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0007584 response to nutrient
Biological Process GO:0042594 response to starvation
Biological Process GO:0042573 retinoic acid metabolic process
Biological Process GO:0008202 steroid metabolic process
Biological Process GO:0052697 xenobiotic glucuronidation
molecular function GO:0019899 enzyme binding
molecular function GO:0004857 enzyme inhibitor activity
molecular function GO:0015020 glucuronosyltransferase activity
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0001972 retinoic acid binding
molecular function GO:0005496 steroid binding
cellular component GO:0070069 cytochrome complex
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0034663 endoplasmic reticulum chaperone complex
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-156580 Phase II - Conjugation of compounds
R-HSA-156588 Glucuronidation
R-HSA-1643685 Disease
R-HSA-211859 Biological oxidations
R-HSA-5579002 Defective UGT1A1 causes hyperbilirubinemia
R-HSA-5579029 Metabolic disorders of biological oxidation enzymes
R-HSA-5668914 Diseases of metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000737 BXGD000005 Abdominal Pain Pathological Conditions, Signs and Symptoms
C0001206 BXGD000033 Acromegaly Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0001430 BXGD000054 Adenoma Neoplasms
C0002312 BXGD000107 alpha-Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002986 BXGD000165 Fabry Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004093 BXGD000251 Asthenia Pathological Conditions, Signs and Symptoms
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007107 BXGD000428 Malignant neoplasm of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0007820 BXGD000491 Cerebrovascular Disorders Nervous System Diseases; Cardiovascular Diseases
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010324 BXGD000663 Crigler Najjar syndrome, type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010414 BXGD000669 Infection by Cryptococcus neoformans Infections
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011226 BXGD000704 Hepatitis D Infection Digestive System Diseases; Infections
C0011616 BXGD000739 Contact Dermatitis Skin and Connective Tissue Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013221 BXGD000804 Drug toxicity Chemically-Induced Disorders
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0016977 BXGD001086 Gall Bladder Diseases Digestive System Diseases
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017551 BXGD001116 Gilbert Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019045 BXGD001269 Hemoglobinopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020433 BXGD001379 Hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020514 BXGD001414 Hyperprolactinemia Nervous System Diseases; Endocrine System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021775 BXGD001512 Intermittent Claudication Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0022353 BXGD001539 Neonatal Jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0022610 BXGD001566 Kernicterus Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027497 BXGD001993 Nausea Pathological Conditions, Signs and Symptoms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028866 BXGD002094 Oculomotor Nerve Paralysis Eye Diseases; Nervous System Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037889 BXGD002709 Hereditary spherocytosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0038187 BXGD002737 Starvation Nutritional and Metabolic Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038362 BXGD002749 Stomatitis Stomatognathic Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039730 BXGD002826 Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041755 BXGD002933 Adverse reaction to drug Chemically-Induced Disorders
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0085096 BXGD003123 Peripheral Vascular Diseases Cardiovascular Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0152266 BXGD003578 Mixed Cellularity Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0152267 BXGD003579 Hodgkin lymphoma, lymphocyte depletion Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0153425 BXGD003641 Malignant tumor of small intestine Digestive System Diseases; Neoplasms
C0153594 BXGD003669 Malignant neoplasm of testis Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162351 BXGD003938 Contact hypersensitivity Skin and Connective Tissue Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0202236 BXGD004086 Triglycerides measurement
C0220597 BXGD004292 Adult Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220615 BXGD004298 Adult Acute Myeloblastic Leukemia Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220644 BXGD004306 Childhood Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0221023 BXGD004369 Cyclic neutropenia Hemic and Lymphatic Diseases
C0231243 BXGD004486 Early complication
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236734 BXGD004823 Caffeine related disorders
C0238196 BXGD004891 Small intestine carcinoma Digestive System Diseases; Neoplasms
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242216 BXGD005141 Biliary calculi Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262584 BXGD005256 Carcinoma, Small Cell Neoplasms
C0264716 BXGD005417 Chronic heart failure Cardiovascular Diseases
C0268138 BXGD005833 Xeroderma Pigmentosum, Complementation Group D Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0268306 BXGD005891 Unconjugated hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0268309 BXGD005893 Inherited disorder of bilirubin metabolism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0270202 BXGD006067 Hemolytic disease of fetus OR newborn due to ABO immunization Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Immune System Diseases; Hemic and Lymphatic Diseases
C0270210 BXGD006068 Lucey-Driscoll syndrome (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0271979 BXGD006283 Thalassemia Intermedia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0278488 BXGD006515 Carcinoma breast stage IV
C0278579 BXGD006537 Cervix carcinoma recurrent Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0278678 BXGD006556 Metastatic Renal Cell Cancer
C0278689 BXGD006563 Recurrent ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0278803 BXGD006593 Adenocarcinoma of small intestine Digestive System Diseases; Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0280962 BXGD006768 Bone Marrow Suppression Hemic and Lymphatic Diseases
C0282193 BXGD006798 Iron Overload Nutritional and Metabolic Diseases
C0311468 BXGD006885 Increased bilirubin level (finding) Pathological Conditions, Signs and Symptoms
C0334277 BXGD007017 Adenocarcinoma, metastatic Neoplasms
C0337443 BXGD007161 Sodium measurement
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0338329 BXGD007169 recurrent childhood brain stem glioma
C0341439 BXGD007408 Chronic liver disease Digestive System Diseases
C0342751 BXGD007542 Generalized glycogen storage disease of infants Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0344395 BXGD007668 Bilirubin measurement
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376154 BXGD007980 Skin callus Skin and Connective Tissue Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0406810 BXGD008374 Carney Complex Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Cardiovascular Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0472762 BXGD008917 Alpha trait thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0472767 BXGD008918 Beta thalassemia intermedia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0473118 BXGD008930 Physiological hyperbilirubinemia (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0489786 BXGD009018 Height
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0520575 BXGD009096 Acute pyelonephritis Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0521585 BXGD009145 Gastrointestinal mucositis Digestive System Diseases; Stomatognathic Diseases
C0523465 BXGD009209 Serum albumin measurement
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0549613 BXGD009390 Biliary tract abnormality Digestive System Diseases
C0557874 BXGD009444 Global developmental delay
C0559506 BXGD009473 Neonatal unconjugated hyperbilirubinemia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0584960 BXGD009579 Factor V Leiden mutation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699889 BXGD009870 Malignant Female Reproductive System Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0700639 BXGD009899 Pyloric Stenosis, Hypertrophic Digestive System Diseases
C0701818 BXGD009903 Choledocholithiasis Digestive System Diseases
C0741494 BXGD010035 Elevated total bilirubin
C0741682 BXGD010039 Premenopausal breast cancer
C0746883 BXGD010153 Febrile Neutropenia Hemic and Lymphatic Diseases
C0750952 BXGD010263 Biliary Tract Cancer Digestive System Diseases; Neoplasms
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0852949 BXGD010957 Arteriopathic disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0854750 BXGD011029 Colorectal cancer recurrent Digestive System Diseases; Neoplasms
C0854776 BXGD011031 Pancreatic carcinoma non-resectable Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0855112 BXGD011074 Diffuse large B-cell lymphoma refractory Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0855197 BXGD011079 Malignant Testicular Germ Cell Tumor Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C0856727 BXGD011108 Cholesterol gallstones Digestive System Diseases
C0857007 BXGD011131 Hyperbilirubinemia, Neonatal Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C0860218 BXGD011222 ABO incompatibility Immune System Diseases; Hemic and Lymphatic Diseases
C0877008 BXGD011325 Enzyme inhibition disorder
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0947622 BXGD011493 Cholecystolithiasis Digestive System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1266194 BXGD011993 Lymphocyte Rich Classical Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1287365 BXGD012174 Bilirubin level result
C1304119 BXGD012325 Chronic stable plaque psoriasis
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1314665 BXGD012386 Serum alkaline phosphatase raised
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1333064 BXGD012587 Classical Hodgkin's Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1334968 BXGD012749 Nodular Lymphocyte Predominant Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1337013 BXGD012876 Differentiated Thyroid Gland Carcinoma
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1443924 BXGD013074 Severe diarrhea Pathological Conditions, Signs and Symptoms
C1445957 BXGD013081 Serum total cholesterol measurement
C1456873 BXGD013129 alpha^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1531394 BXGD013294 Perinatal jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1565662 BXGD013402 Acute Kidney Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1565885 BXGD013403 Direct Hyperbilirubinemia, Neonatal Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1565886 BXGD013404 Indirect Hyperbilirubinemia, Neonatal Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1565887 BXGD013405 Newborn physiological jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1611743 BXGD013456 Familial (FPAH)
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1827377 BXGD013770 Slow acetylator due to N-acetyltransferase enzyme variant
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1859236 BXGD015867 Prolonged neonatal jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1860834 BXGD016006 Infantile muscular hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1861453 BXGD016049 Pseudohyperkalemia Cardiff Nutritional and Metabolic Diseases
C1866173 BXGD016380 BILIRUBIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 1
C1879645 BXGD016579 Adverse Event by CTCAE Category
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1963167 BXGD016686 Memory Impairment, CTCAE 3.0
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2347747 BXGD017040 Adult Classical Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2609414 BXGD017182 Acute kidney injury Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2931132 BXGD017963 Crigler Najjar syndrome, type 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2939465 BXGD018182 Deficiency of glucose-6-phosphate dehydrogenase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3502107 BXGD019039 Breastfeeding Jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C3544205 BXGD019109 Ovarian clear cell carcinoma
C3553270 BXGD019166 DIARRHEA 6
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3826044 BXGD019710 Lymphoblastic leukemia in children
C3841475 BXGD019800 beta^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3888554 BXGD019980 UGT1A1 gene polymorphism
C4303163 BXGD022553 Autoimmune hepatitis type 2
C4321477 BXGD022752 Sickle Cell-SS Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4524268 BXGD023104 Advanced lung cancer
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4553765 BXGD023551 Memory Impairment, CTCAE 5.0
C4684861 BXGD023572 Recurrent Malignant Glioma Neoplasms
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721698 BXGD023763 Metastatic Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722172 BXGD023791 Primary differentiated carcinoma of thyroid gland
C4733092 BXGD023907 estrogen receptor-negative breast cancer
C4744564 BXGD023947 Metastatic Colorectal Carcinoma Digestive System Diseases; Neoplasms
C4755308 BXGD024094 Familial cervical artery dissection
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0000332 Fisetin 286.24
BXGC0000363 Galangin 270.24
BXGC0000368 Gallic acid 170.12
BXGC0000383 (S)-Naringenin 272.25
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000573 Dantron 240.21
BXGC0000663 Papain 206.28
BXGC0000681 Umbelliferone 162.14
BXGC0000819 Nopol 166.26
BXGC0001778 Scutellarein 286.24
BXGC0001881 Chrysophanol 254.24
BXGC0001899 Daidzein 254.24
BXGC0002052 Aesculetin 178.14
BXGC0002071 Apigenin 270.24
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0002757 3,7,11-Trimethyl-1,2,6,10-dodecatrienol 222.37
BXGC0003485 Naphthalen-1-ol 144.17
BXGC0003707 Estrogen 268.36
BXGC0003773 Estriol 288.38
BXGC0003949 Thymunic acid 150.22
BXGC0004378 3-Hydroxyflavone 238.24
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0004577 4-tert-Butylphenol 150.22
BXGC0004712 Methylparaben 152.15
BXGC0004713 Ethylparaben 166.17
BXGC0004719 2-Biphenylol 170.21
BXGC0005654 Naringin 580.53
BXGC0005683 Quercetin 302.24
BXGC0005702 2H-1-Benzopyran-2-one 146.15
BXGC0005745 Irilone 298.25
BXGC0005756 Propyl gallate 212.2
BXGC0005793 Baicalein 270.24
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0005879 Eugenol 164.2
BXGC0006276 Tigogenin 416.64
BXGC0006291 Scopoletin 192.17
BXGC0006362 Estrone 270.37
BXGC0006366 trans-Ferulic acid 194.18
BXGC0006372 Ergocalciferol 396.65
BXGC0006923 D-Citronellol 156.27
BXGC0007029 Emodin 270.24
BXGC0007393 2-Bornanol 154.25
BXGC0007521 Citronellol 156.27
BXGC0007528 p-Menthan-3-ol 156.27
BXGC0007535 5-Isopropyl-2-methylphenol 150.22
BXGC0007821 Linalool 154.25
BXGC0008167 Chrysin 254.24
BXGC0012228 Vitamin D 384.64
BXGC0012243 Ukonan D 151.16
BXGC0013544 Naphthalen-1-Amine 143.07
BXGC0017489 Oleandomycin 687.42
BXGC0017965 4-Hydroxycoumarins 162.03
BXGC0018843 Quinalizarin 272.03
BXGC0019164 Raloxifene 473.17
BXGC0019293 Norethynodrel 298.19
BXGC0020800 Testosterone 288.21
BXGC0022978 Biphenyl-4-Amine 169.09
BXGC0024264 Ergosterol 396.34
BXGC0025204 Anthraquinone 208.05
BXGC0025862 Levothyroxine 776.69
BXGC0026391 Naloxone 327.15
BXGC0027421 Paclitaxel 853.33
BXGC0028046 Resacetophenone 152.05
BXGC0028314 alpha-terpineol 154.14
BXGC0030783 4-Butylphenol 150.1
BXGC0030901 Morphine 285.14
BXGC0032175 4-pentylphenol 164.12
BXGC0032207 Disogenin 414.31
BXGC0032351 Nalorphine 311.15
BXGC0034783 Doxorubicin 543.17
BXGC0034968 Dienestrol 266.13
BXGC0035201 Quinidine 324.18
BXGC0035676 morphine-3-glucuronide 461.17
BXGC0037718 Ethacrynic Acid 302.01
BXGC0037915 isoborneol 154.14
BXGC0039397 Athraquinones A 240.04
BXGC0042222 Propranolol 259.16
BXGC0042460 Betanaphthol 144.06
BXGC0043236 1,5-dihydroxyanthraquinone 240.04
BXGC0044080 Scutellarin 462.08
BXGC0044334 P-Nitrophenol 139.03
BXGC0047169 Hymecromone 176.05
BXGC0048389 Catechin 290.08
BXGC0052712 Anthraflavicacid 240.04
BXGC0053114 Propylparaben 180.08
BXGC0053494 Quinizarin 240.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein