acompound

Showing entry for 8-Hydroxydaidzein

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0005782
Compound Name	8-Hydroxydaidzein
Structure
Formula	C15H10O5
InchiKey	BMZFZTMWBCFKSS-UHFFFAOYSA-N
SMILES	OC1=CC=C(C=C1)C1=COC2=C(C=CC(O)=C2O)C1=O
Inchi	InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-15-10(13(11)18)5-6-12(17)14(15)19/h1-7,16-17,19H
IUPAC	7,8-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
Molecular Weight	270.24
Pubchem Id	5466139
Chembl Id	CHEMBL242739

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006941	Arachidonate 5-lipoxygenase	reviewed	Enzyme	ALOX5	-	900	-	-
reviewed	BXGT006400	Prostaglandin G/H synthase 1	reviewed		PTGS1	-	>1.50e+5	-	-
reviewed	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	-	>1.50e+5	-	-
reviewed	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	-	6600	-	-
reviewed	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	-	>1000000	-	-
reviewed	BXGT007687	Tyrosinase	reviewed		Tyr	-	11210	-	-
reviewed	BXGT013686	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	reviewed	Kinase	PFKFB3	-	670	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	IC50	'>'	1000000	nM
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	reviewed	Enzyme	XDH	IC50	'='	6600	nM
P14916	BXGT008066	Urease subunit alpha	reviewed	-	ureA	IC50	'>'	1480000	nM
P69996	BXGT011656	Urease subunit beta	reviewed	-	ureB	IC50	'>'	1480000	nM
P11344	BXGT007687	Tyrosinase	reviewed	-	Tyr	IC50	'='	11210	nM
P14916	BXGT008066	Urease subunit alpha	reviewed	-	ureA	IC50	'='	140000	nM
P69996	BXGT011656	Urease subunit beta	reviewed	-	ureB	IC50	'='	140000	nM
P14916	BXGT008066	Urease subunit alpha	reviewed	-	ureA	Inhibition	'='	81	%
P69996	BXGT011656	Urease subunit beta	reviewed	-	ureB	Inhibition	'='	81	%
Q16875	BXGT013686	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	reviewed	Kinase	PFKFB3	IC50	'='	670	nM
Q16875	BXGT013686	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	reviewed	Kinase	PFKFB3	Inhibition	'>'	30	%
Q16875	BXGT013686	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	reviewed	Kinase	PFKFB3	Inhibition	'='	40	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00022	Oat	Avena sativa	Cereals and cereal products
BXGF00085	Soy bean	Glycine max	Soy
BXGF00819	Pulses		Pulses
BXGF01314	Thalictrum flavum	Thalictrum flavum	Medicinal Plant
BXGF01563	Echinops transiliensis	Echinops transiliensis	Others
BXGF01914	Lantana montevidensis	Lantana montevidensis	Human Edible Plant
BXGF01996	Senecio suaveolens	Senecio suaveolens	Others
BXGF02026	Olearia pimeleoides	Olearia pimeleoides	Others
BXGF02056	Muscari botryoides	Muscari botryoides	Medicinal Plant
BXGF02084	Dasycladus vermicularis	Dasycladus vermicularis	Others
BXGF02257	Teclea gerrardii	Teclea gerrardii	Medicinal Plant
BXGF02332	Salvia castanea	Salvia castanea	Medicinal Plant
BXGF03605	Stellaria holostea	Stellaria holostea	Human Edible Plant
BXGF05108	Sophora mollis	Sophora mollis	Medicinal Plant
BXGF05241	Dalbergia assamica	Dalbergia assamica	Others
BXGF06023	Hedysarum theinum	Hedysarum theinum	Others
BXGF06157	Haemanthus amarylloides	Haemanthus amarylloides	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}