Showing entry for Genistin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0005917
Compound NameGenistin
Structure
FormulaC21H20O10
InchiKeyZCOLJUOHXJRHDI-UHFFFAOYSA-N
SMILESOCC1OC(OC2=CC(O)=C3C(=O)C(=COC3=C2)C2=CC=C(O)C=C2)C(O)C(O)C1O
InchiInChI=1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6,8,15,18-24,26-28H,7H2
IUPAC5-hydroxy-3-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one
Molecular Weight432.38
Pubchem Id5284639
Chembl IdCHEMBL1364260
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL1364260
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 29092 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 25118 nM
P38398 BXGT010037 Breast cancer type 1 susceptibility protein reviewed Enzyme BRCA1 Potency - 8912 nM
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency - 11220 nM
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 reviewed Transporter NPC1 Potency '=' 5623 nM
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 5623 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 631 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 14581 nM
P02791 BXGT005965 Ferritin light chain reviewed - FTL Potency '=' 50118 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 39810 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 31622 nM
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 29092 nM
P00811 BXGT005666 Beta-lactamase reviewed - ampC Potency '=' 79432 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 9200 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 23934 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 398 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 29092 nM
Q13148 BXGT013318 TAR DNA-binding protein 43 reviewed - TARDBP Potency - 281 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00085 Soy bean Glycine max Soy
BXGF00146 Sour cherry Prunus cerasus Fruits
BXGF00251 Other soy product Soy
BXGF00370 White lupine Lupinus albus Pulses
BXGF00649 Soy sauce Soy
BXGF00650 Miso Soy
BXGF00651 Tofu Soy
BXGF00691 Soy milk Soy
BXGF00722 Soy yogurt Soy
BXGF00819 Pulses Pulses
BXGF00823 Fruits Fruits
BXGF01245 Amomum villosum Amomum villosum Medicinal Plant
BXGF01902 Amomum longiligulare Amomum longiligulare Medicinal Plant
BXGF02238 Amomum xanthioides Amomum xanthioides Medicinal Plant
BXGF03152 Sophora japonica Sophora japonica Medicinal Plant
BXGF04029 Lupinus luteus Lupinus luteus Medicinal Plant
BXGF04767 Piptanthus nepalensis Piptanthus nepalensis Medicinal Plant
BXGF04943 Pueraria lobata Pueraria lobata Medicinal Plant
BXGF06079 Pueraria montana var. lobata Pueraria montana var. lobata Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease