Showing entry for NPC intracellular cholesterol transporter 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004127
Protein NameNPC intracellular cholesterol transporter 1
Uniport IdO15118
GeneNPC1
Gene Id4864
DomainNPC1_N; Patched; Sterol-sensing
Pfam PF16414   PF02460   PF12349  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04142 Lysosome
5. Organismal Systems 5.4 Digestive system hsa04979 Cholesterol metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007628 adult walking behavior
Biological Process GO:0006914 autophagy
Biological Process GO:0008206 bile acid metabolic process
Biological Process GO:0071404 cellular response to low-density lipoprotein particle stimulus
Biological Process GO:0071383 cellular response to steroid hormone stimulus
Biological Process GO:0033344 cholesterol efflux
Biological Process GO:0042632 cholesterol homeostasis
Biological Process GO:0008203 cholesterol metabolic process
Biological Process GO:0030301 cholesterol transport
Biological Process GO:0006897 endocytosis
Biological Process GO:0090150 establishment of protein localization to membrane
Biological Process GO:0032367 intracellular cholesterol transport
Biological Process GO:0034383 low-density lipoprotein particle clearance
Biological Process GO:0007041 lysosomal transport
Biological Process GO:0031579 membrane raft organization
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:0016242 negative regulation of macroautophagy
Biological Process GO:0006486 protein glycosylation
Biological Process GO:0046686 response to cadmium ion
Biological Process GO:0042493 response to drug
Biological Process GO:0046718 viral entry into host cell
molecular function GO:0015485 cholesterol binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0015248 sterol transporter activity
molecular function GO:0004888 transmembrane signaling receptor activity
molecular function GO:0001618 virus receptor activity
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005794 Golgi apparatus
cellular component GO:1905103 integral component of lysosomal membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0031902 late endosome membrane
cellular component GO:0005765 lysosomal membrane
cellular component GO:0005764 lysosome
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005635 nuclear envelope
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance
R-HSA-382551 Transport of small molecules
R-HSA-8964038 LDL clearance
R-HSA-8964043 Plasma lipoprotein clearance
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001429 BXGD000053 Adenolymphoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0004936 BXGD000295 Mental disorders Mental Disorders
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006131 BXGD000373 Branchioma Neoplasms
C0006309 BXGD000392 Brucellosis Infections
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007384 BXGD000463 Cataplexy Nervous System Diseases; Mental Disorders
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011168 BXGD000700 Deglutition Disorders Digestive System Diseases; Otorhinolaryngologic Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013264 BXGD000808 Muscular Dystrophy, Duchenne Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013421 BXGD000837 Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0017083 BXGD001090 Gangliosidoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0018681 BXGD001214 Headache Pathological Conditions, Signs and Symptoms
C0018780 BXGD001218 Hearing Loss, High-Frequency Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0019214 BXGD001307 Hepatosplenomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Hemic and Lymphatic Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0022353 BXGD001539 Neonatal Jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0023508 BXGD001675 White Blood Cell Count procedure
C0023522 BXGD001680 Leukodystrophy, Metachromatic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0023794 BXGD001700 Lipoidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024266 BXGD001754 Lymphocytic Choriomeningitis Infections; Nervous System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025521 BXGD001876 Inborn Errors of Metabolism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0026470 BXGD001903 Monoclonal Gammopathy of Undetermined Significance Immune System Diseases; Hemic and Lymphatic Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026850 BXGD001942 Muscular Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028064 BXGD002068 Niemann-Pick Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029089 BXGD002107 Ophthalmoplegia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036489 BXGD002620 Sea-Blue Histiocyte Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0037899 BXGD002710 Sphingolipidoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0039292 BXGD002807 Tangier Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0041341 BXGD002918 Tuberous Sclerosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0080032 BXGD003105 Pleural Effusion, Malignant Neoplasms; Respiratory Tract Diseases
C0085078 BXGD003118 Lysosomal Storage Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0085400 BXGD003165 Neurofibrillary degeneration (morphologic abnormality)
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0086565 BXGD003295 Liver Dysfunction Digestive System Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0153014 BXGD003612 Non-arthropod borne lymphocytic choriomeningitis Infections; Nervous System Diseases
C0153382 BXGD003627 Malignant neoplasm of oropharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0153392 BXGD003630 Malignant neoplasm of nasopharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0162292 BXGD003930 External Ophthalmoplegia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0200633 BXGD004040 Neutrophil count (procedure)
C0200638 BXGD004043 Eosinophil count procedure
C0200641 BXGD004044 Blood basophil count (lab test)
C0202236 BXGD004086 Triglycerides measurement
C0205682 BXGD004105 Waist-Hip Ratio
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0220756 BXGD004338 Niemann-Pick Disease, Type C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0221757 BXGD004472 alpha 1-Antitrypsin Deficiency Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0235031 BXGD004714 Neurologic Symptoms Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235950 BXGD004790 Zinc deficiency Nutritional and Metabolic Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238301 BXGD004909 Cancer of Nasopharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0240225 BXGD005025 Liver mass
C0240952 BXGD005066 Dysarthria, Scanning Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0240991 BXGD005069 Ataxia, Sensory Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0242917 BXGD005200 Filoviridae Infections Infections
C0262404 BXGD005236 Cerebellar degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0264542 BXGD005398 Adhesion of pleura Respiratory Tract Diseases
C0264611 BXGD005403 Apraxia of Phonation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0266463 BXGD005675 Lissencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0267971 BXGD005798 Storage disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0267990 BXGD005800 Adult-onset obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0268242 BXGD005864 Niemann-Pick Disease, Type A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0268247 BXGD005866 Niemann-Pick Disease, Type D Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0278161 BXGD006504 Ataxia, Motor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278952 BXGD006616 Nasopharyngeal cancer recurrent Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279748 BXGD006693 Undifferentiated carcinoma of nasopharynx
C0280214 BXGD006718 stage, nasopharyngeal cancer Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0282687 BXGD006826 Hemorrhagic Fever, Ebola Infections
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0334070 BXGD006986 Maturation defect
C0334254 BXGD007010 Lymphoepithelial carcinoma Neoplasms
C0338473 BXGD007182 Neuroaxonal Dystrophies Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0339693 BXGD007279 Internal Ophthalmoplegia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0348489 BXGD007875 Other sphingolipidosis Nutritional and Metabolic Diseases
C0376338 BXGD007990 Diagnosis, Psychiatric Mental Disorders
C0392885 BXGD008071 High density lipoprotein measurement
C0427190 BXGD008611 Ataxia, Truncal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0454596 BXGD008842 Dysarthria, Spastic Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0454597 BXGD008843 Dysarthria, Flaccid Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0454598 BXGD008844 Dysarthria, Mixed Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0520966 BXGD009128 Abnormal coordination Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0521158 BXGD009130 Recurrent tumor
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542223 BXGD009274 Loss of speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0549523 BXGD009386 Oropharynx (excludes nasopharynx)
C0553694 BXGD009409 Oropharyngeal disorders Digestive System Diseases; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0557874 BXGD009444 Global developmental delay
C0562350 BXGD009476 Hip circumference
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0745103 BXGD010114 Hyperlipoproteinemia Type IIa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0750937 BXGD010259 Ataxia, Appendicular Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0750940 BXGD010260 Tremor, Rubral Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751072 BXGD010312 Frontotemporal Lobar Degeneration Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0751401 BXGD010427 Ophthalmoparesis Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0751870 BXGD010622 Heredodegenerative Disorders, Nervous System Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0815107 BXGD010861 psychological distress
C0857490 BXGD011150 Granulocyte count
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1285291 BXGD012170 Fetal ascites Pathological Conditions, Signs and Symptoms
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1368683 BXGD012900 Epithelioma Neoplasms
C1519689 BXGD013245 Tumor Promotion Pathological Conditions, Signs and Symptoms; Neoplasms
C1563666 BXGD013383 Dysarthria, Guttural Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1563937 BXGD013397 Atherogenesis Cardiovascular Diseases
C1611743 BXGD013456 Familial (FPAH)
C1709527 BXGD013626 B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1
C1843366 BXGD014575 NIEMANN-PICK DISEASE, TYPE C2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C1843369 BXGD014577 Vertical supranuclear gaze palsy
C1843373 BXGD014578 Foam cells in visceral organs and CNS
C1843921 BXGD014620 Postural instability Nervous System Diseases
C1845076 BXGD014708 Lymphoproliferative Syndrome, X-Linked, 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1850363 BXGD015135 Niemann-Pick Disease, Nova Scotian Type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C1850496 BXGD015147 Neuronal loss in central nervous system
C1856560 BXGD015617 Bone-marrow foam cells
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1859236 BXGD015867 Prolonged neonatal jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1881236 BXGD016584 Interstitial Disease
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2231324 BXGD016959 Brucellosis, Pulmonary Infections
C2349952 BXGD017065 Oropharyngeal Carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2713319 BXGD017493 Arylsulfatase A Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2986658 BXGD018234 Diffuse Intrinsic Pontine Glioma
C3179349 BXGD018550 Gastrointestinal Stromal Sarcoma Digestive System Diseases; Neoplasms
C3179455 BXGD018552 Niemann-Pick Disease, Type C1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C4017105 BXGD020407 NIEMANN-PICK DISEASE, TYPE C1, ADULT FORM
C4017106 BXGD020408 NIEMANN-PICK DISEASE, TYPE C1, JUVENILE FORM
C4025017 BXGD021526 Fatal liver failure in infancy Digestive System Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4553743 BXGD023548 Spasticity, CTCAE
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000194 Sanguinarine 332.33
BXGC0000203 Piperine 285.34
BXGC0000430 Gossypol 518.55
BXGC0000436 Glycerol 92.09
BXGC0000530 Hydroquinone 110.11
BXGC0000964 6-Methylscutellarein 300.26
BXGC0000999 Peucedanin 258.27
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001428 Piperlongine 317.34
BXGC0001476 Girinimbine 263.33
BXGC0001495 (R)-Roemerine 279.33
BXGC0001742 Eupafolin 316.26
BXGC0001767 (E)-Resveratrol 228.25
BXGC0001899 Daidzein 254.24
BXGC0001962 Hesperetin 302.28
BXGC0002043 Acacetin 284.26
BXGC0002071 Apigenin 270.24
BXGC0002797 Nodakenetic 246.26
BXGC0003221 Xanthyletin 228.24
BXGC0003452 Pectolinarigenin 314.29
BXGC0003690 Glucokinin 764.94
BXGC0003776 Flavones 222.24
BXGC0003852 Nigrin B 506.47
BXGC0005624 Genistein 270.24
BXGC0005917 Genistin 432.38
BXGC0005919 Biochanin A 284.27
BXGC0005920 Biochanin A 7-glucoside 446.4
BXGC0005921 Daidzin 416.38
BXGC0006389 Rotenone 394.42
BXGC0007029 Emodin 270.24
BXGC0008168 7-Methylchrysin 268.26
BXGC0008169 5,7-Dimethylchrysin 282.29
BXGC0008713 Dihydrooroxylin 286.28
BXGC0012352 Chelerythrine 348.12
BXGC0012377 Nagilactone B 364.15
BXGC0014455 Fanchinin 622.3
BXGC0014649 4',7-Dimethoxy-5-Hydroxygenistein 298.08
BXGC0014695 Loratadine 382.14
BXGC0015659 Cladrin 298.08
BXGC0016891 Nortriptyline 263.17
BXGC0017277 Aurin 290.09
BXGC0017933 Sulfuretin 270.05
BXGC0018397 beta-1,4-mannan 180.06
BXGC0019348 Angustibalin 304.13
BXGC0020302 Hortiacine 317.12
BXGC0020737 Protoapigenone 286.05
BXGC0020873 Aromaticin 246.13
BXGC0021255 4-[(3S)-8,8-Dimethyl-3,4-Dihydro-2H-Pyrano[2,3-F]Chromen-3-Yl]Benzene-1,3-Diol 324.14
BXGC0021600 Ilepcimide 259.12
BXGC0022544 Digoxin 780.43
BXGC0023497 Pterostilbene 256.11
BXGC0024208 3-(3,4-Dimethoxyphenyl)-7-Methoxychromen-4-One 312.1
BXGC0024413 Emetine 480.3
BXGC0024428 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 333.15
BXGC0024770 Digoxigenin 390.24
BXGC0025050 Diethyl 2,6-Dimethyl-4-Phenylpyridine-3,5-Dicarboxylate 327.15
BXGC0025200 2-Anilinonaphthalene-1,4-Dione 249.08
BXGC0025757 Calcimycin 523.27
BXGC0027259 Tryptanthrin 248.06
BXGC0027421 Paclitaxel 853.33
BXGC0028067 Enniatin B 639.41
BXGC0028204 Cinobufotalin 458.23
BXGC0028278 Rutaecarpine 287.11
BXGC0029582 1,2-Dimethoxyanthracene-9,10-Dione 268.07
BXGC0029585 Biochanin A, Dimethyl Ether 312.1
BXGC0030248 2-(4-Hydroxyphenyl)Chromen-4-One 238.06
BXGC0030388 Cholestan-3Beta,5Alpha,6Beta-Triol 420.36
BXGC0030696 2,3-Dimethoxyxanthen-9-One 256.07
BXGC0031622 Podofilox 414.13
BXGC0033776 Cycloheximide 281.16
BXGC0033820 2-Propan-2-Ylfuro[3,2-G]Chromen-7-One 228.08
BXGC0034576 2-(4-Hydroxyphenyl)Ethyl 4-Methoxybenzoate 272.1
BXGC0035776 BRUCEOLIDE 438.15
BXGC0036860 Helenalin 262.12
BXGC0037016 4'-Methoxyflavone 252.08
BXGC0038197 2-Methoxyphenazine 210.08
BXGC0038316 Cholesterol 386.35
BXGC0038546 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] 2-Methylprop-2-Enoate 346.14
BXGC0039507 Digitoxigenin 374.25
BXGC0039520 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] (E)-2-Methylbut-2-Enoate 360.16
BXGC0040155 Triptolide 360.16
BXGC0040332 (3S,4S)-4-[(3,4-Dimethoxyphenyl)Methyl]-3-[(4-Hydroxy-3-Methoxyphenyl)Methyl]Oxolan-2-One 372.16
BXGC0040936 Sid26657808 284.07
BXGC0041070 Taxol C 847.38
BXGC0041900 Cytochalasin B 479.27
BXGC0042091 Dequalinium 456.33
BXGC0042510 Fluoxetine 309.13
BXGC0042870 Piceatannol 244.07
BXGC0043126 Nicardipine 479.21
BXGC0044375 Ononin 430.13
BXGC0044857 Sp-600125 220.06
BXGC0045132 n.a 616.4
BXGC0045746 Diphenyleneiodonium 278.97
BXGC0045812 Trifluoperazine 407.16
BXGC0046281 Cucurbitacin B 558.32
BXGC0047086 4-[(2R)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]Piperidine-2,6-Dione 281.16
BXGC0048801 Sid24823998 254.09
BXGC0049137 3-Benzoyl-7-Methoxychromen-2-One 280.07
BXGC0050008 Strophanthidin 404.22
BXGC0050102 1-Hydroxy-2-Methoxyanthracene-9,10-Dione 254.06
BXGC0050123 Cepharanthine 606.27
BXGC0050129 Prunetrin 446.12
BXGC0050194 alpha-D-Mannose 180.06
BXGC0051184 Calycosin 284.07
BXGC0051524 Ouabain 584.28
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein