Showing entry for L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0007438
Compound NameL-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid
Structure
FormulaC12H12N2O2
InchiKeyFSNCEEGOMTYXKY-UHFFFAOYSA-N
SMILESOC(=O)C1CC2=C(CN1)NC1=CC=CC=C21
InchiInChI=1S/C12H12N2O2/c15-12(16)10-5-8-7-3-1-2-4-9(7)14-11(8)6-13-10/h1-4,10,13-14H,5-6H2,(H,15,16)
IUPAC1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylic acid
Molecular Weight216.24
Pubchem Id98285
Chembl IdCHEMBL149177
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL149177
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P22300 BXGT008750 Gamma-aminobutyric acid receptor subunit gamma-2 reviewed - GABRG2 IC50 '=' 22000 nM
P10064 BXGT007533 Gamma-aminobutyric acid receptor subunit alpha-3 reviewed - GABRA3 IC50 '=' 22000 nM
P08219 BXGT006749 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed - GABRA1 IC50 '=' 22000 nM
P20237 BXGT008552 Gamma-aminobutyric acid receptor subunit alpha-4 reviewed - GABRA4 IC50 '=' 22000 nM
P08220 BXGT006750 Gamma-aminobutyric acid receptor subunit beta-1 reviewed - GABRB1 IC50 '=' 22000 nM
P10063 BXGT007532 Gamma-aminobutyric acid receptor subunit alpha-2 reviewed - GABRA2 IC50 '=' 22000 nM
P16305 BXGT008215 Gamma-aminobutyric acid receptor subunit alpha-6 reviewed - Gabra6 Inhibition - - -
P27681 BXGT009196 Gamma-aminobutyric acid receptor subunit gamma-3 reviewed - Gabrg3 Inhibition - - -
P63080 BXGT011492 Gamma-aminobutyric acid receptor subunit beta-3 reviewed - Gabrb3 Inhibition - - -
Q9D6F4 BXGT020259 Gamma-aminobutyric acid receptor subunit alpha-4 reviewed - Gabra4 Inhibition - - -
P22933 BXGT008819 Gamma-aminobutyric acid receptor subunit delta reviewed - Gabrd Inhibition - - -
P26049 BXGT009086 Gamma-aminobutyric acid receptor subunit alpha-3 reviewed - Gabra3 Inhibition - - -
Q9JLF1 BXGT020834 Gamma-aminobutyric acid receptor subunit theta reviewed - Gabrq Inhibition - - -
P62812 BXGT011459 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed - Gabra1 Inhibition - - -
A2AMW3 BXGT001075 Gamma-aminobutyric acid (GABA) A receptor, subunit epsilon unreviewed - Gabre Inhibition - - -
P22723 BXGT008798 Gamma-aminobutyric acid receptor subunit gamma-2 reviewed - Gabrg2 Inhibition - - -
Q9R0Y8 BXGT021410 Gamma-aminobutyric acid receptor subunit gamma-1 reviewed - Gabrg1 Inhibition - - -
P50571 BXGT010810 Gamma-aminobutyric acid receptor subunit beta-1 reviewed - Gabrb1 Inhibition - - -
Q8QZW7 BXGT018675 Gamma-aminobutyric acid receptor subunit pi reviewed - Gabrp Inhibition - - -
P26048 BXGT009085 Gamma-aminobutyric acid receptor subunit alpha-2 reviewed - Gabra2 Inhibition - - -
Q8BHJ7 BXGT017911 Gamma-aminobutyric acid receptor subunit alpha-5 reviewed - Gabra5 Inhibition - - -
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 Inhibition '=' 26 %
Q9Z1J7 BXGT022405 Amino acid transporter unreviewed - Slc1a5 Inhibition '>=' 25 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00054 Lemon Citrus limon Fruits
BXGF00056 Mandarin orange (Clementine, Tangerine) Citrus reticulata Fruits
BXGF00057 Sweet orange Citrus sinensis Fruits
BXGF00173 Garden tomato (var.) Solanum lycopersicum var. lycopersicum Vegetables
BXGF02965 Arabidopsis thaliana Arabidopsis thaliana Medicinal Plant
BXGF05289 Allium macrostemon Allium macrostemon Medicinal Plant
BXGF06004 Allium chinense Allium chinense Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease