Showing entry for Gamma-aminobutyric acid receptor subunit alpha-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006749
Protein NameGamma-aminobutyric acid receptor subunit alpha-1
Uniport IdP08219
GeneGABRA1
Gene Id780973
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:1902476 chloride transmembrane transport
Biological Process GO:0007214 gamma-aminobutyric acid signaling pathway
Biological Process GO:1904862 inhibitory synapse assembly
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0050877 nervous system process
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0060078 regulation of postsynaptic membrane potential
Biological Process GO:0007165 signal transduction
Biological Process GO:0051932 synaptic transmission, GABAergic
molecular function GO:0005254 chloride channel activity
molecular function GO:0004890 GABA-A receptor activity
molecular function GO:0022851 GABA-gated chloride ion channel activity
molecular function GO:0005237 inhibitory extracellular ligand-gated ion channel activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
cellular component GO:0034707 chloride channel complex
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0032590 dendrite membrane
cellular component GO:1902711 GABA-A receptor complex
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043005 neuron projection
cellular component GO:0098794 postsynapse
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002867 Lappaurin 284.74
BXGC0003817 Miltiorone 282.38
BXGC0007438 L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid 216.24
BXGC0018397 beta-1,4-mannan 180.06
BXGC0034669 2-Isopropyl-8-Methyl-5,6-Dihydro-Phenanthrene-3,4-Dione 266.13
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein