acompound

Showing entry for 5-Aminolevulinic acid

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0012311
Compound Name	5-Aminolevulinic acid
Structure
Formula	C5H9NO3
InchiKey	ZGXJTSGNIOSYLO-UHFFFAOYSA-N
SMILES	NCC(=O)CCC(O)=O
Inchi	InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)
IUPAC	5-amino-4-oxopentanoic acid
Molecular Weight	131.13
Pubchem Id	137
Chembl Id	CHEMBL601

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	reviewed	Enzyme	ALAD	approved	inducer

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
A0A657M1C3	BXGT023978	Peptide ABC transporter permease	unreviewed	BL313_09825	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008943	Gamma-aminobutyric acid receptor subunit rho-1	reviewed	Ion channel	GABRR1	-	12900	-	-
reviewed	BXGT007865	Xaa-Pro dipeptidase	reviewed	Enzyme	PEPD	960000	-	-	-
reviewed	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	790000	-	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	reviewed	Enzyme	ALAD	Km	'='	253000	nM
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	reviewed	Enzyme	ALAD	k cat	'='	0	s-1
P24046	BXGT008943	Gamma-aminobutyric acid receptor subunit rho-1	reviewed	Ion channel	GABRR1	IC50	'='	12900	nM
P12955	BXGT007865	Xaa-Pro dipeptidase	reviewed	Enzyme	PEPD	Ki	'='	960000	nM
P46059	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	Ki	'='	790000	nM
P00811	BXGT005666	Beta-lactamase	reviewed	-	ampC	Potency	'='	22387	nM
Q16348	BXGT013627	Solute carrier family 15 member 2	reviewed	Transporter	SLC15A2	Activity	-	-	-
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	reviewed	Enzyme	ALAD	Retention	'='	80	%
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	125	nM
Q9UIF8	BXGT021718	Bromodomain adjacent to zinc finger domain protein 2B	reviewed	-	BAZ2B	Potency	-	707	nM
Q63424	BXGT016071	Solute carrier family 15 member 2	reviewed	-	Slc15a2	Ki	'='	230000	nM
P51574	BXGT010860	Solute carrier family 15 member 1	reviewed	-	Slc15a1	Ki	'='	2200000	nM
P46059	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	Activity	-	-	-
Q13304	BXGT013337	Uracil nucleotide/cysteinyl leukotriene receptor	reviewed	G-protein coupled receptor	GPR17	Inhibition	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00022	Oat	Avena sativa	Cereals and cereal products
BXGF00205	Corn	Zea mays	Cereals and cereal products

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}