acompound

Showing entry for Proline

General Compound Information
BXGC Id	BXGC0012322
Compound Name	Proline
Structure
Formula	C5H9NO2
InchiKey	ONIBWKKTOPOVIA-UHFFFAOYSA-N
SMILES	OC(=O)C1CCCN1
Inchi	InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
IUPAC	pyrrolidine-2-carboxylic acid
Molecular Weight	115.13
Pubchem Id	614
Chembl Id	CHEMBL72275

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50000105

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT009831	Glutamate receptor ionotropic, NMDA 1	reviewed		Grin1	-	17200	-	-

CHEMBL

CHEMBL72275

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9F4F7	BXGT020344	4'-phosphopantetheinyl transferase ffp	reviewed	-	ffp	Potency	'='	56234	nM
Q13951	BXGT013407	Core-binding factor subunit beta	reviewed	-	CBFB	Potency	-	14125	nM
Q01196	BXGT012575	Runt-related transcription factor 1	reviewed	Transcription factor	RUNX1	Potency	-	14125	nM
Q93RY0	BXGT019524	Putative dihydropicolinate synthase	unreviewed	-	SCO6292	Inhibition	'='	0	%
P35439	BXGT009831	Glutamate receptor ionotropic, NMDA 1	reviewed	-	Grin1	IC50	'='	17200	nM
Q9UBT6	BXGT021664	DNA polymerase kappa	reviewed	-	POLK	Potency	-	42284	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00006	Garden onion	Allium cepa	Vegetables
BXGF00008	Garlic	Allium sativum	Herbs and Spices
BXGF00022	Oat	Avena sativa	Cereals and cereal products
BXGF00027	Chinese mustard	Brassica juncea	Vegetables
BXGF00034	Broccoli	Brassica oleracea var. italica	Vegetables
BXGF00036	Turnip	Brassica rapa var. rapa	Herbs and Spices
BXGF00065	Cucumber	Cucumis sativus	Gourds
BXGF00088	Barley	Hordeum vulgare	Cereals and cereal products
BXGF00129	Parsnip	Pastinaca sativa	Vegetables
BXGF00162	Red raspberry	Rubus idaeus	Fruits
BXGF00169	Rye	Secale cereale	Cereals and cereal products
BXGF00174	Eggplant	Solanum melongena	Vegetables
BXGF00175	Potato	Solanum tuberosum	Vegetables
BXGF00178	Spinach	Spinacia oleracea	Vegetables
BXGF00181	Dandelion	Taraxacum officinale	Herbs and Spices
BXGF00225	Swiss chard	Beta vulgaris ssp. cicla	Vegetables
BXGF00230	Carrot	Daucus carota ssp. sativus	Vegetables
BXGF00246	Red beetroot	Beta vulgaris var. rubra	Vegetables
BXGF00337	Ginkgo nuts	Ginkgo biloba	Herbs and Spices
BXGF00380	White mustard	Sinapis alba	Herbs and Spices
BXGF00519	Wheat	Triticum	Cereals and cereal products
BXGF00826	Sunburst squash (pattypan squash)	Cucurbita pepo var. clypeata	Gourds
BXGF00827	Green zucchini	Cucurbita pepo var. cylindrica	Gourds
BXGF00828	Yellow zucchini	Cucurbita pepo var. cylindrica	Gourds
BXGF00829	Green bell pepper	Capsicum annuum	Vegetables
BXGF00830	Yellow bell pepper	Capsicum annuum	Vegetables
BXGF00831	Orange bell pepper	Capsicum annuum	Vegetables
BXGF00832	Red bell pepper	Capsicum annuum	Vegetables
BXGF00834	Yellow wax bean	Phaseolus vulgaris	Pulses
BXGF00835	Green bean	Phaseolus vulgaris	Pulses
BXGF00836	Saskatoon berry	Amelanchier alnifolia	Fruits
BXGF00837	Nanking cherry	Prunus tomentosa	Fruits
BXGF00838	Japanese pumpkin	Cucurbita maxima	Gourds
BXGF00839	White cabbage	Brassica oleracea L. var. capitata L. f. alba DC.	Vegetables
BXGF00840	Romaine lettuce	Lactuca sativa L. var. longifolia	Vegetables
BXGF01140	Angelica gigas	Angelica gigas	Medicinal Plant
BXGF01668	Taraxacum platycarpum	Taraxacum platycarpum	Medicinal Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF02152	Taraxacum borealisinense	Taraxacum borealisinense	Others
BXGF03630	Taraxacum coreanum	Taraxacum coreanum	Others
BXGF04310	Taraxacum mongolicum	Taraxacum mongolicum	Medicinal Plant
BXGF04820	Panax ginseng	Panax ginseng	0
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant
BXGF05297	Isatis tinctoria	Isatis tinctoria	Medicinal Plant
BXGF05421	Tussilago farfara	Tussilago farfara	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}