Showing entry for Glutamate receptor ionotropic, NMDA 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009831
Protein NameGlutamate receptor ionotropic, NMDA 1
Uniport IdP35439
GeneGrin1
Gene Id24408
DomainANF_receptor; CaM_bdg_C0; Lig_chan; Lig_chan-Glu_bd
Pfam PF01094   PF10562   PF00060   PF10613  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008344 adult locomotory behavior
Biological Process GO:0008306 associative learning
Biological Process GO:0055074 calcium ion homeostasis
Biological Process GO:0097553 calcium ion transmembrane import into cytosol
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0006812 cation transport
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0071287 cellular response to manganese ion
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0001661 conditioned taste aversion
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0035235 ionotropic glutamate receptor signaling pathway
Biological Process GO:0007612 learning
Biological Process GO:0007611 learning or memory
Biological Process GO:0007616 long-term memory
Biological Process GO:0060179 male mating behavior
Biological Process GO:0007613 memory
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0050905 neuromuscular process
Biological Process GO:0008355 olfactory learning
Biological Process GO:0021586 pons maturation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0010524 positive regulation of calcium ion transport into cytosol
Biological Process GO:0010942 positive regulation of cell death
Biological Process GO:2001056 positive regulation of cysteine-type endopeptidase activity
Biological Process GO:1902952 positive regulation of dendritic spine maintenance
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:1903428 positive regulation of reactive oxygen species biosynthetic process
Biological Process GO:1900149 positive regulation of Schwann cell migration
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0060134 prepulse inhibition
Biological Process GO:0018964 propylene metabolic process
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0051290 protein heterotetramerization
Biological Process GO:1903539 protein localization to postsynaptic membrane
Biological Process GO:0050770 regulation of axonogenesis
Biological Process GO:0010646 regulation of cell communication
Biological Process GO:0048814 regulation of dendrite morphogenesis
Biological Process GO:0048169 regulation of long-term neuronal synaptic plasticity
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0048168 regulation of neuronal synaptic plasticity
Biological Process GO:0043523 regulation of neuron apoptotic process
Biological Process GO:0043576 regulation of respiratory gaseous exchange
Biological Process GO:0051963 regulation of synapse assembly
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0014075 response to amine
Biological Process GO:0001975 response to amphetamine
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0045471 response to ethanol
Biological Process GO:0060992 response to fungicide
Biological Process GO:1905429 response to glycine
Biological Process GO:0043278 response to morphine
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0048511 rhythmic process
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0035176 social behavior
Biological Process GO:0001964 startle response
Biological Process GO:0001967 suckling behavior
Biological Process GO:0035249 synaptic transmission, glutamatergic
Biological Process GO:0008542 visual learning
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0005262 calcium channel activity
molecular function GO:0005509 calcium ion binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0005261 cation channel activity
molecular function GO:0019899 enzyme binding
molecular function GO:0016595 glutamate binding
molecular function GO:0022849 glutamate-gated calcium ion channel activity
molecular function GO:0035254 glutamate receptor binding
molecular function GO:0016594 glycine binding
molecular function GO:0004970 ionotropic glutamate receptor activity
molecular function GO:0015276 ligand-gated ion channel activity
molecular function GO:0099507 ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
molecular function GO:0042165 neurotransmitter binding
molecular function GO:0004972 NMDA glutamate receptor activity
molecular function GO:0019902 phosphatase binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
molecular function GO:0022843 voltage-gated cation channel activity
cellular component GO:0009986 cell surface
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0032590 dendrite membrane
cellular component GO:0044307 dendritic branch
cellular component GO:0043197 dendritic spine
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0060076 excitatory synapse
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0017146 NMDA selective glutamate receptor complex
cellular component GO:0098688 parallel fiber to Purkinje cell synapse
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
cellular component GO:0043083 synaptic cleft
cellular component GO:0097060 synaptic membrane
cellular component GO:0008021 synaptic vesicle
cellular component GO:0030672 synaptic vesicle membrane
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0000279 L-Alanine 89.09
BXGC0000288 L-Proline 115.13
BXGC0000436 Glycerol 92.09
BXGC0000456 (S)-2-Azetidinecarboxylic acid 101.1
BXGC0000982 L-Homocysteine 135.19
BXGC0001588 Arecaidine 141.17
BXGC0001626 3-Aminopropanoic acid 89.09
BXGC0001642 Tricholomic acid 160.13
BXGC0002390 Spermine 202.34
BXGC0003113 N-trans-p-Coumaroyltyramine 283.32
BXGC0003196 Aripiprazole 448.39
BXGC0003296 1,3-Diaminopropane 74.12
BXGC0003566 2-Aminoadipic acid 161.16
BXGC0003705 Chloride 35.45
BXGC0004139 Sperminidine 145.25
BXGC0004760 2-Phenylethylamine 121.18
BXGC0005683 Quercetin 302.24
BXGC0005794 Benzylamine 107.15
BXGC0005874 Racemethionine 149.21
BXGC0006162 L-Glutamic acid 147.13
BXGC0006183 L-Cystine 240.3
BXGC0006186 L-Aspartic acid 133.1
BXGC0006272 D-2-Aminobutanoic acid 103.12
BXGC0008059 1-Aminocyclopropanecarboxylic acid 101.1
BXGC0012322 Proline 115.13
BXGC0014019 (2S,3S)-2-Amino-3-Hydroxybutanedioic Acid 149.03
BXGC0014659 D-Alanine 89.05
BXGC0018397 beta-1,4-mannan 180.06
BXGC0020954 2-phenylquinoline 205.09
BXGC0024569 (1S,2R)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid 159.05
BXGC0025204 Anthraquinone 208.05
BXGC0025485 Transtorine 189.04
BXGC0029437 (1R,2S)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid 159.05
BXGC0030028 (D)-Serine 105.04
BXGC0035865 (+)-Pentazocine 285.21
BXGC0036441 Quisqualate 189.04
BXGC0036476 D-Glutamate 147.05
BXGC0038154 D-Aspartate 133.04
BXGC0038837 Pseudohypericin 520.08
BXGC0039032 Glutamic Acid 145.04
BXGC0040506 D-Proline 115.06
BXGC0042317 5-methoxyindole-2-carboxylic acid 191.06
BXGC0042462 Cysteine 121.02
BXGC0042510 Fluoxetine 309.13
BXGC0042574 Ibogaine 310.2
BXGC0049061 Pentazocine 285.21
BXGC0049516 Kainic Acid 213.1
BXGC0050194 alpha-D-Mannose 180.06
BXGC0053391 N-(4-Hydroxyphenethyl)Cinnamamide 267.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein