acompound

Showing entry for phenylglyoxylic acid

General Compound Information
BXGC Id	BXGC0013795
Compound Name	phenylglyoxylic acid
Structure
Formula	C8H6O3
InchiKey	FAQJJMHZNSSFSM-UHFFFAOYSA-N
SMILES	O=C(c1ccccc1)C(=O)O
Inchi	InChI=1S/C8H6O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5H,(H,10,11)
IUPAC	2-oxo-2-phenylacetic acid
Molecular Weight	150.03
Pubchem Id	11915
Chembl Id	CHEMBL950

Targets of Information Source

DrugBank

DB02279

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q9UJM8	BXGT021726	Hydroxyacid oxidase 1	reviewed	-	HAO1	experimental	-

PDB

173

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P00175	BXGT005478	Cytochrome b2, mitochondrial	reviewed	CYB2	-	-	-	-	-
Q2IR47	BXGT014102	Extracellular ligand-binding receptor	unreviewed	RPB_4630	-	-	-	-	-
Q122C7	BXGT013237	Solute-binding protein Bpro_4736	reviewed	Bpro_4736	-	-	-	-	-
O52792	BXGT023675	4-hydroxymandelate oxidase	reviewed	hmo	-	-	-	-	-

Binding DB

50102174

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed		PTPN1	-	2700000	-	-
reviewed	BXGT011178	C-terminal-binding protein 2	reviewed	Transcription factor	CTBP2	-	>300000	-	-

CHEMBL

CHEMBL950

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O54937	BXGT004736	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	reviewed	-	Pdk4	Stimulation	'='	85	%
Q64536	BXGT016122	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	reviewed	-	Pdk2	Stimulation	'='	85	%
B5DFI9	BXGT002164	Pdk3 protein	unreviewed	-	Pdk3	Stimulation	'='	85	%
Q63065	BXGT016059	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	-	Pdk1	Stimulation	'='	85	%
O54937	BXGT004736	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	reviewed	-	Pdk4	PDH active/PDH total	'='	87	%
Q64536	BXGT016122	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	reviewed	-	Pdk2	PDH active/PDH total	'='	87	%
B5DFI9	BXGT002164	Pdk3 protein	unreviewed	-	Pdk3	PDH active/PDH total	'='	87	%
Q63065	BXGT016059	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	-	Pdk1	PDH active/PDH total	'='	87	%
O54937	BXGT004736	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	reviewed	-	Pdk4	Stimulation	'='	42	%
Q64536	BXGT016122	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	reviewed	-	Pdk2	Stimulation	'='	42	%
B5DFI9	BXGT002164	Pdk3 protein	unreviewed	-	Pdk3	Stimulation	'='	42	%
Q63065	BXGT016059	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	-	Pdk1	Stimulation	'='	42	%
O54937	BXGT004736	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	reviewed	-	Pdk4	Stimulation	'='	219	%
Q64536	BXGT016122	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	reviewed	-	Pdk2	Stimulation	'='	219	%
B5DFI9	BXGT002164	Pdk3 protein	unreviewed	-	Pdk3	Stimulation	'='	219	%
Q63065	BXGT016059	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	-	Pdk1	Stimulation	'='	219	%
O54937	BXGT004736	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	reviewed	-	Pdk4	PDH active/PDH total	'='	38	%
Q64536	BXGT016122	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	reviewed	-	Pdk2	PDH active/PDH total	'='	38	%
B5DFI9	BXGT002164	Pdk3 protein	unreviewed	-	Pdk3	PDH active/PDH total	'='	38	%
Q63065	BXGT016059	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	-	Pdk1	PDH active/PDH total	'='	38	%
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	IC50	'='	2700000	nM
P56545	BXGT011178	C-terminal-binding protein 2	reviewed	Transcription factor	CTBP2	IC50	'>'	300000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00204	Common grape	Vitis vinifera	Fruits

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}