acompound

Showing entry for Dihomo-Gamma-Linolenic Acid

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0019792
Compound Name	Dihomo-Gamma-Linolenic Acid
Structure
Formula	C20H34O2
InchiKey	HOBAELRKJCKHQD-QNEBEIHSSA-N
SMILES	CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
Inchi	InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-
IUPAC	(8Z,11Z,14Z)-icosa-8,11,14-trienoic acid
Molecular Weight	306.26
Pubchem Id	5280581
Chembl Id	CHEMBL465183

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P23219	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	investigational; nutraceutical	inhibitor
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	investigational; nutraceutical	-

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P05979	BXGT006400	Prostaglandin G/H synthase 1	reviewed	PTGS1	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT018813	Oxoeicosanoid receptor 1	reviewed	G-protein coupled receptor	OXER1	3700	-	-	-
reviewed	BXGT005645	Trypsin	reviewed		-	-	>200000	-	-
reviewed	BXGT007950	Tissue factor	reviewed	Receptor	F3	-	75000	-	-
reviewed	BXGT007950	Tissue factor	reviewed	Receptor	F3	-	30000	-	-
reviewed	BXGT018813	Oxoeicosanoid receptor 1	reviewed	G-protein coupled receptor	OXER1	-	2000	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	reviewed	Nuclear receptor	PPARD	IC50	'='	4300	nM
P00761	BXGT005645	Trypsin	reviewed	-		IC50	'>'	200000	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	39810	nM
P13726	BXGT007950	Tissue factor	reviewed	Receptor	F3	IC50	'='	30000	nM
P08709	BXGT006818	Coagulation factor VII	reviewed	Enzyme	F7	IC50	'='	30000	nM
P13726	BXGT007950	Tissue factor	reviewed	Receptor	F3	IC50	'='	75000	nM
P08709	BXGT006818	Coagulation factor VII	reviewed	Enzyme	F7	IC50	'='	75000	nM
P49798	BXGT010745	Regulator of G-protein signaling 4	reviewed	Enzyme modulator	RGS4	Potency	-	1337	nM
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	reviewed	Nuclear receptor	PPARA	IC50	'='	1400	nM
Q8TDS5	BXGT018813	Oxoeicosanoid receptor 1	reviewed	G-protein coupled receptor	OXER1	IC50	'='	2000	nM
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	reviewed	Nuclear receptor	PPARG	IC50	'='	2400	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00855	Nerium oleander	Nerium oleander	Medicinal Plant
BXGF06070	Perilla frutescens	Perilla frutescens	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}