acompound

Showing entry for (-)-Catechin

General Compound Information
BXGC Id	BXGC0020098
Compound Name	(-)-Catechin
Structure
Formula	C15H14O6
InchiKey	PFTAWBLQPZVEMU-HIFRSBDPSA-N
SMILES	Oc1cc2O[C@@H](c3ccc(c(c3)O)O)[C@@H](Cc2c(c1)O)O
Inchi	InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1
IUPAC	(2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
Molecular Weight	290.08
Pubchem Id	73160
Chembl Id	CHEMBL200715

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50236527

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006400	Prostaglandin G/H synthase 1	reviewed		PTGS1	-	5300	-	-
reviewed	BXGT006400	Prostaglandin G/H synthase 1	reviewed		PTGS1	-	30800	-	-
reviewed	BXGT022265	Sialidase-2	reviewed	Enzyme	NEU2	-	>1000000	-	-
reviewed	BXGT007700	Glucose-6-phosphate 1-dehydrogenase	reviewed		ZWF1	-	>1000000	-	-
reviewed	BXGT010923	6-phosphogluconate dehydrogenase, decarboxylating	reviewed	Enzyme	PGD	-	>1000000	-	-
reviewed	BXGT006400	Prostaglandin G/H synthase 1	reviewed		PTGS1	-	-	48700	-

CHEMBL

CHEMBL200715

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q965D7	BXGT019602	Beta-hydroxyacyl-ACP dehydratase	unreviewed	-	fabZ	Activity	-	-	-
Q965D5	BXGT019600	Enoyl-acyl-carrier protein reductase	unreviewed	-	fabI	Activity	-	-	-
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	Ke	'='	1770	nM
P05979	BXGT006400	Prostaglandin G/H synthase 1	reviewed	-	PTGS1	Activity	'='	8	%
P05979	BXGT006400	Prostaglandin G/H synthase 1	reviewed	-	PTGS1	Kd	'='	48700	nM
P05979	BXGT006400	Prostaglandin G/H synthase 1	reviewed	-	PTGS1	IC50	'='	5300	nM
P08581	BXGT006794	Hepatocyte growth factor receptor	reviewed	Kinase	MET	Inhibition	-	-	-
P05979	BXGT006400	Prostaglandin G/H synthase 1	reviewed	-	PTGS1	Activity	-	-	-
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	Ke	'='	2400	nM
P05979	BXGT006400	Prostaglandin G/H synthase 1	reviewed	-	PTGS1	IC50	'='	30800	nM
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	Ke	'='	3600	nM
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	Activity	-	-	-
P11412	BXGT007700	Glucose-6-phosphate 1-dehydrogenase	reviewed	-	ZWF1	IC50	'>'	1000000	nM
Q965D6	BXGT019601	3-oxoacyl-acyl-carrier protein reductase	unreviewed	-	fabG	Activity	-	-	-
P52209	BXGT010923	6-phosphogluconate dehydrogenase, decarboxylating	reviewed	Enzyme	PGD	IC50	'>'	1000000	nM
P06278	BXGT006431	Alpha-amylase	reviewed	-	amyS	Activity	-	-	-
Q9Y3R4	BXGT022265	Sialidase-2	reviewed	Enzyme	NEU2	IC50	'>'	1000000	nM
P16098	BXGT008191	Beta-amylase	reviewed	-	BMY1	Activity	-	-	-
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Activity	'='	30	%
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Activity	'='	65	%
P00591	BXGT005592	Pancreatic triacylglycerol lipase	reviewed	-	PNLIP	Inhibition	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00022	Oat	Avena sativa	Cereals and cereal products
BXGF00027	Chinese mustard	Brassica juncea	Vegetables
BXGF00087	Sea-buckthornberry	Hippophae rhamnoides	Fruits
BXGF00118	Nutmeg	Myristica fragrans	Herbs and Spices
BXGF00129	Parsnip	Pastinaca sativa	Vegetables
BXGF00151	Pomegranate	Punica granatum	Fruits
BXGF00198	Adzuki bean	Vigna angularis	Pulses
BXGF00201	Climbing bean	Vigna umbellata	Pulses
BXGF00204	Common grape	Vitis vinifera	Fruits
BXGF00206	Ginger	Zingiber officinale	Herbs and Spices
BXGF00213	European cranberry	Vaccinium oxycoccos	Fruits
BXGF00337	Ginkgo nuts	Ginkgo biloba	Herbs and Spices
BXGF00369	Sacred lotus	Nelumbo nucifera	Vegetables
BXGF00380	White mustard	Sinapis alba	Herbs and Spices
BXGF00857	Mitracarpus scaber	Mitracarpus scaber	Others
BXGF00886	Abutilon theophrasti	Abutilon theophrasti	Medicinal Plant
BXGF00931	Ipomoea digitata	Ipomoea digitata	Medicinal Plant
BXGF01031	Epimedium sagittatum	Epimedium sagittatum	Medicinal Plant
BXGF01034	Annona cornifolia	Annona cornifolia	Human Edible Plant
BXGF01074	Centella asiatica	Centella asiatica	Medicinal Plant
BXGF01126	Polygonum cuspidatum	Polygonum cuspidatum	Medicinal Plant
BXGF01174	Salvia syriaca	Salvia syriaca	Others
BXGF01185	Aloe vera	Aloe vera	Medicinal Plant
BXGF01204	Solanum laxum	Solanum laxum	Medicinal Plant
BXGF01222	Ocimum tenuiflorum	Ocimum tenuiflorum	Medicinal Plant
BXGF01283	Crataegus pinnatifida	Crataegus pinnatifida	Medicinal Plant
BXGF01314	Thalictrum flavum	Thalictrum flavum	Medicinal Plant
BXGF01325	Murraya exotica	Murraya exotica	Medicinal Plant
BXGF01374	Balanops australiana	Balanops australiana	Others
BXGF01443	Trachycarpus fortunei	Trachycarpus fortunei	Medicinal Plant
BXGF01456	Eucalyptus melliodora	Eucalyptus melliodora	Others
BXGF01555	Scutellaria amoena	Scutellaria amoena	Medicinal Plant
BXGF01563	Echinops transiliensis	Echinops transiliensis	Others
BXGF01597	Senegalia catechu	Senegalia catechu	Medicinal Plant
BXGF01609	Epimedium sempervirens	Epimedium sempervirens	Others
BXGF01614	Goniothalamus malayanus	Goniothalamus malayanus	Others
BXGF01721	Humulus lupulus	Humulus lupulus	Medicinal Plant
BXGF01743	Uncaria macrophylla	Uncaria macrophylla	Medicinal Plant
BXGF01767	Uncaria rhynchophylla	Uncaria rhynchophylla	Medicinal Plant
BXGF01834	Lysimachia mauritiana	Lysimachia mauritiana	Others
BXGF01883	Swertia franchetiana	Swertia franchetiana	Medicinal Plant
BXGF01896	Lilium brownii	Lilium brownii	Medicinal Plant
BXGF01900	Aloe ferox	Aloe ferox	Medicinal Plant
BXGF01914	Lantana montevidensis	Lantana montevidensis	Human Edible Plant
BXGF01954	Amomum tsao-ko	Amomum tsao-ko	Human Edible Plant
BXGF01989	Helipterum roseum	Helipterum roseum	Others
BXGF01996	Senecio suaveolens	Senecio suaveolens	Others
BXGF02026	Olearia pimeleoides	Olearia pimeleoides	Others
BXGF02050	Hedysarum connatum	Hedysarum connatum	Others
BXGF02056	Muscari botryoides	Muscari botryoides	Medicinal Plant
BXGF02084	Dasycladus vermicularis	Dasycladus vermicularis	Others
BXGF02088	Zanthoxylum tetraspermum	Zanthoxylum tetraspermum	Medicinal Plant
BXGF02125	Artemisia assoana	Artemisia assoana	Others
BXGF02183	Dumortiera hirsuta	Dumortiera hirsuta	Medicinal Plant
BXGF02204	Apocynum venetum	Apocynum venetum	Medicinal Plant
BXGF02246	Lepisorus ussuriensis	Lepisorus ussuriensis	Medicinal Plant
BXGF02257	Teclea gerrardii	Teclea gerrardii	Medicinal Plant
BXGF02295	Alstonia spathulata	Alstonia spathulata	Others
BXGF02326	Phoebe pittieri	Phoebe pittieri	Others
BXGF02332	Salvia castanea	Salvia castanea	Medicinal Plant
BXGF02361	Hypericum laricifolium	Hypericum laricifolium	Medicinal Plant
BXGF02370	Epimedium pubescens	Epimedium pubescens	Medicinal Plant
BXGF02410	Adiantum lunulatum	Adiantum lunulatum	Medicinal Plant
BXGF02460	Peltostigma guatemalense	Peltostigma guatemalense	Others
BXGF02491	Acacia adunca	Acacia adunca	Others
BXGF02505	Pinus sylvestris	Pinus sylvestris	Medicinal Plant
BXGF02515	Viguiera incana	Viguiera incana	Others
BXGF02529	Astragalus sempervirens	Astragalus sempervirens	Others
BXGF02554	Marrubium anisodon	Marrubium anisodon	Medicinal Plant
BXGF02593	Wikstroemia retusa	Wikstroemia retusa	Others
BXGF02604	Agrimonia pilosa	Agrimonia pilosa	Medicinal Plant
BXGF02606	Naucleopsis ternstroemiiflora	Naucleopsis ternstroemiiflora	Others
BXGF02612	Mosla chinensis	Mosla chinensis	Medicinal Plant
BXGF02642	Vigna umbeuata	Vigna umbeuata	Others
BXGF02786	Rubus coreanus	Rubus coreanus	Human Edible Plant
BXGF02802	Araiostegiella perdurans	Araiostegiella perdurans	Others
BXGF02881	Epimedium grandiflorum	Epimedium grandiflorum	Medicinal Plant
BXGF03132	Ancistrocladus korupensis	Ancistrocladus korupensis	Medicinal Plant
BXGF03158	Rheum officinale	Rheum officinale	Medicinal Plant
BXGF03243	Elsholtzia ciliata	Elsholtzia ciliata	Medicinal Plant
BXGF03398	Solanum nigrum	Solanum nigrum	Medicinal Plant
BXGF03426	Rhodiola crenulata	Rhodiola crenulata	Medicinal Plant
BXGF03476	Hylocomium splendens	Hylocomium splendens	Others
BXGF03488	Paeonia suffruticosa	Paeonia suffruticosa	Medicinal Plant
BXGF03583	Epimedium koreanum	Epimedium koreanum	Medicinal Plant
BXGF03605	Stellaria holostea	Stellaria holostea	Human Edible Plant
BXGF03610	Bistorta officinalis	Bistorta officinalis	Medicinal Plant
BXGF03763	Millettia laurentii	Millettia laurentii	Medicinal Plant
BXGF03765	Alcea rosea	Alcea rosea	Medicinal Plant
BXGF03947	Rumex maritimus	Rumex maritimus	Medicinal Plant
BXGF03988	Rheum coreanum	Rheum coreanum	Others
BXGF04053	Smilax china	Smilax china	Medicinal Plant
BXGF04062	Spatholobus suberectus	Spatholobus suberectus	Medicinal Plant
BXGF04080	Persicaria orientalis	Persicaria orientalis	Medicinal Plant
BXGF04200	Euphorbia hirta	Euphorbia hirta	Medicinal Plant
BXGF04209	Chaenomeles sinensis	Chaenomeles sinensis	Medicinal Plant
BXGF04224	Bistorta manshuriensis	Bistorta manshuriensis	Others
BXGF04235	Rubus chingii	Rubus chingii	Food Plant
BXGF04258	Rubia cordifolia	Rubia cordifolia	Medicinal Plant
BXGF04341	Sanguisorba officinalis	Sanguisorba officinalis	Medicinal Plant
BXGF04349	Monodora tenuifolia	Monodora tenuifolia	Human Edible Plant
BXGF04361	Cynomorium songaricum	Cynomorium songaricum	Medicinal Plant
BXGF04382	Murraya paniculata	Murraya paniculata	Medicinal Plant
BXGF04539	Rheum palmatum	Rheum palmatum	Medicinal Plant
BXGF04631	Aloe spicata	Aloe spicata	Medicinal Plant
BXGF04817	Euonymus alatus	Euonymus alatus	Medicinal Plant
BXGF04864	Uncaria sinensis	Uncaria sinensis	Medicinal Plant
BXGF04881	Fallopia multiflora	Fallopia multiflora	Medicinal Plant
BXGF04886	Boehmeria nivea	Boehmeria nivea	Medicinal Plant
BXGF04896	Kokoona reflexa	Kokoona reflexa	Others
BXGF04926	Aloe africana	Aloe africana	Medicinal Plant
BXGF05083	Viguiera decurrens	Viguiera decurrens	Medicinal Plant
BXGF05145	Sideritis brevibracteata	Sideritis brevibracteata	Human Edible Plant
BXGF05160	Chaenomeles speciosa	Chaenomeles speciosa	Medicinal Plant
BXGF05184	Maesa ramentacea	Maesa ramentacea	Medicinal Plant
BXGF05187	Calostephane divaricata	Calostephane divaricata	Others
BXGF05241	Dalbergia assamica	Dalbergia assamica	Others
BXGF05242	Euphorbia cornigera	Euphorbia cornigera	Others
BXGF05269	Hypericum perforatum	Hypericum perforatum	Medicinal Plant
BXGF05274	Lilium lancifolium	Lilium lancifolium	Medicinal Plant
BXGF05368	Salvia yosgadensis	Salvia yosgadensis	Others
BXGF05370	Epimedium brevicornu	Epimedium brevicornu	Others
BXGF05428	Sideroxylon cubense	Sideroxylon cubense	Others
BXGF05442	Zanthoxylum bungeanum	Zanthoxylum bungeanum	Medicinal Plant
BXGF05526	Salvia miltiorrhiza	Salvia miltiorrhiza	Medicinal Plant
BXGF05571	Ziziphus jujuba	Ziziphus jujuba	Medicinal Plant
BXGF05654	Pinus strobus	Pinus strobus	Medicinal Plant
BXGF05728	Persicaria perfoliata	Persicaria perfoliata	Medicinal Plant
BXGF05730	Alpinia blepharocalyx	Alpinia blepharocalyx	Medicinal Plant
BXGF05742	Caragana aurantiaca	Caragana aurantiaca	Others
BXGF05764	Eucalyptus jenseni	Eucalyptus jenseni	Others
BXGF05787	Smilax glabra	Smilax glabra	Medicinal Plant
BXGF05790	Glycyrrhiza uralensis	Glycyrrhiza uralensis	Medicinal Plant
BXGF05831	Rosa laevigata	Rosa laevigata	Medicinal Plant
BXGF05862	Premna odorata	Premna odorata	Medicinal Plant
BXGF05869	Salacia lehmbachii	Salacia lehmbachii	Medicinal Plant
BXGF05877	Rheum tanguticum	Rheum tanguticum	Medicinal Plant
BXGF05931	Lilium pumilum	Lilium pumilum	Medicinal Plant
BXGF05954	Pluchea odorata	Pluchea odorata	Others
BXGF06023	Hedysarum theinum	Hedysarum theinum	Others
BXGF06033	Euonymus tingens	Euonymus tingens	Medicinal Plant
BXGF06037	Cotyledon secunda	Cotyledon secunda	Others
BXGF06075	Zanthoxylum schinifolium	Zanthoxylum schinifolium	Medicinal Plant
BXGF06157	Haemanthus amarylloides	Haemanthus amarylloides	Others
BXGF06161	Epimedium wushanense	Epimedium wushanense	Medicinal Plant
BXGF06214	Uncaria gambir	Uncaria gambir	Medicinal Plant
BXGF06227	Rauvolfia vomitoria	Rauvolfia vomitoria	Medicinal Plant
BXGF06237	Gnetum latifolium	Gnetum latifolium	Medicinal Plant
BXGF06238	Gardenia jasminoides	Gardenia jasminoides	Medicinal Plant
BXGF06243	Bauhinia racemosa	Bauhinia racemosa	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}