Showing entry for Sialidase-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022265
Protein NameSialidase-2
Uniport IdQ9Y3R4
GeneNEU2
Gene Id4759
DomainBNR_2
Pfam PF13088  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00511 Other glycan degradation
1. Metabolism 1.3 Lipid metabolism hsa00600 Sphingolipid metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051692 cellular oligosaccharide catabolic process
Biological Process GO:0006689 ganglioside catabolic process
Biological Process GO:0006687 glycosphingolipid metabolic process
Biological Process GO:0009313 oligosaccharide catabolic process
molecular function GO:0052794 exo-alpha-(2->3)-sialidase activity
molecular function GO:0052795 exo-alpha-(2->6)-sialidase activity
molecular function GO:0052796 exo-alpha-(2->8)-sialidase activity
molecular function GO:0004308 exo-alpha-sialidase activity
cellular component GO:1902494 catalytic complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1660662 Glycosphingolipid metabolism
R-HSA-392499 Metabolism of proteins
R-HSA-4085001 Sialic acid metabolism
R-HSA-428157 Sphingolipid metabolism
R-HSA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-446219 Synthesis of substrates in N-glycan biosythesis
R-HSA-556833 Metabolism of lipids
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C2062441 BXGD016897 Influenza A
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000340 Kaempferol 286.24
BXGC0000461 Tricetin 302.24
BXGC0000573 Dantron 240.21
BXGC0000963 Sakuranetin 286.28
BXGC0001023 7,4'-Dihydroxyflavone 254.24
BXGC0001778 Scutellarein 286.24
BXGC0002043 Acacetin 284.26
BXGC0002071 Apigenin 270.24
BXGC0003705 Chloride 35.45
BXGC0003813 Genkwanin 284.26
BXGC0004965 Rhein 284.22
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0005793 Baicalein 270.24
BXGC0006306 Myricetin 318.24
BXGC0006635 Luteolin 286.24
BXGC0007029 Emodin 270.24
BXGC0008167 Chrysin 254.24
BXGC0020098 (-)-Catechin 290.08
BXGC0020340 9,10-anthraquinone 2-carboxylic acid 252.04
BXGC0025887 5-Hydroxyflavone 238.06
BXGC0028115 5,7-Dihydroxy-2-(2-Hydroxyphenyl)Chromen-4-One 270.05
BXGC0044778 Oseltamivir 312.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein