acompound

Showing entry for 2-Naphthalen-1-Ylacetic Acid

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0022447
Compound Name	2-Naphthalen-1-Ylacetic Acid
Structure
Formula	C12H10O2
InchiKey	PRPINYUDVPFIRX-UHFFFAOYSA-N
SMILES	OC(=O)Cc1cccc2c1cccc2
Inchi	InChI=1S/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)
IUPAC	2-naphthalen-1-ylacetic acid
Molecular Weight	186.07
Pubchem Id	6862
Chembl Id	CHEMBL428495

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P63208	BXGT011507	S-phase kinase-associated protein 1	reviewed	Enzyme	SKP1	experimental	-

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P13689	BXGT007944	Auxin-binding protein 1	reviewed	ABP1	-	-	-	150	-
Q570C0	BXGT015108	Protein TRANSPORT INHIBITOR RESPONSE 1	reviewed	TIR1	-	-	-	-	-
P24666	BXGT008986	Low molecular weight phosphotyrosine protein phosphatase	reviewed	ACP1	-	-	-	-	-
P00592	BXGT005593	Phospholipase A2, major isoenzyme	reviewed	PLA2G1B	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed		Akr1b1	-	32000	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P10828	BXGT007624	Thyroid hormone receptor beta	reviewed	Nuclear receptor	THRB	Potency	-	44668	nM
P07943	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed	-	Akr1b1	IC50	'='	32000	nM
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	reviewed	Nuclear receptor	PPARG	Potency	-	39810	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	1157	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	92	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	'='	10000	nM
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	reviewed	-	IDH1	Potency	-	580	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	43277	nM
Q9UNA4	BXGT021785	DNA polymerase iota	reviewed	-	POLI	Potency	-	89125	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF04334	Carapichea ipecacuanha	Carapichea ipecacuanha	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}